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BJÖRK
Protocols
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STRUCTURAL BIOLOGY
RELATED GROUPS
Clemons Lab | Hoelz Lab
Jensen Lab | Mayo Lab
Rees Lab | Voorhees Lab
Protein Expression Center
Molecular Observatory
Cryo-EM Facility
SSRL beamtime/Crystal trays

WEBSITES OF INTEREST
Caltech
Biological Imaging Center

Rosen Bioengineering Center
External fellowships for grad student
Fellowships Resources for postdocs
Integrated structural biology platforms

History of Crystallography
WebofScience | CITLibrary | PubMed

CITdirectory | CITaccess | BBE Seminars

CRYSTALLOGRAPHY RESOURCES

California Institute of Technology
Division of Biology and Biological Engineering
MC 114-96 | 1200 E. California Blvd.,
Pasadena, CA 91125
(626) 395-8351 phone | 626) 792-3683 fax
murphym [at] caltech dot edu

 


@bjorkmanlab

Our laboratory is interested in immune recognition of viral pathogens. We are investigating the immune responses against HIV-1 and other viruses, most recently SARS-CoV-2, in order to develop improved therapeutics and/or vaccines. We use X-ray crystallography, electron microscopy, and biochemistry to study pathogen glycoproteins and host immune proteins. Using structural information and alternate antibody architectures, we are engineering antibody-based reagents with increased potency and breadth. We are also investigating the structural correlates of potent antibody-mediated neutralization of HIV-1, SARS-CoV-2, and hepatitis C virus to better understand what leads to naturally-occurring potent neutralizing antibodies.

 



HIVRADP01 2019 Project:
Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1Antibodies

- Webinar: Pamela Bjorkman: Viruses, Antiviral
and Vaccines, 04/2020

- The HIV Life Cycle

Donate in memory of Will Lange, 2016
Earnest C. Watson Lecture, 2015
TEDxCaltech: New Anti-HIV Agents, 2013
Traveling with Purpose - Volunteering in India, 2012
World AIDS Day - News Conf on KNBC-TV, 2012
LA Theatre Works: Rosalind Franklin, 2011

Rachel Galimidi wins Clauser Doctoral Prize, 2016
Louise Scharf, AIDS Vaccine Barcelona, 2013
Gwen Owens, Crystals in space, 2013
Gwen Owens in CASIS video, 2013