@bjorkmanlab
Our laboratory is interested in immune recognition of viral pathogens. We are investigating the immune responses against HIV-1 and other viruses, most recently SARS-CoV-2, in order to develop improved therapeutics and/or vaccines. We use X-ray crystallography, electron microscopy, and biochemistry to study pathogen glycoproteins and host immune proteins. Using structural information and alternate antibody architectures, we are engineering antibody-based reagents with increased potency and breadth. We are also investigating the structural correlates of potent antibody-mediated neutralization of HIV-1, SARS-CoV-2, and hepatitis C virus to better understand what leads to naturally-occurring potent neutralizing antibodies.
Anthony West has developed Variant Database,
a SARS-CoV-2 mutation pattern query tool, 06/2021

HIVRADP01 2019 Project:
Developing Immunogens to Elicit Broadly Neutralizing anti-HIV-1Antibodies
-Pearl Meister Greengard Prize: Pamela Bjorkman, 2021
- Webinar: Pamela Bjorkman: Viruses, Antiviral
and Vaccines, 04/2020
- The HIV Life Cycle
–Donate in memory of Will Lange, 2016
–Earnest C. Watson Lecture, 2015
–TEDxCaltech: New Anti-HIV Agents, 2013
–Traveling with Purpose - Volunteering in India, 2012
–World AIDS Day - News Conf on KNBC-TV, 2012
–LA Theatre Works: Rosalind Franklin, 2011
–Magnus Hoffmann wins Clauser Doctoral Prize, 2022
–Rachel Galimidi wins Clauser Doctoral Prize, 2016
–Louise Scharf, AIDS Vaccine Barcelona, 2013
–Gwen Owens, Crystals in space, 2013
–Gwen Owens in CASIS video, 2013