Our Research

The Gradinaru Lab uses advanced technologies such as optogenetics, CLARITY, physiology, imaging, and behavior to understand and develop therapies for neurological diseases.

NIH Director's Blog highlights recent G-Lab research

Scientific American features our work on Delivery Vectors that Cross the Blood-Brain Barrier

Short talk on Deep Brain Stimulation, Optogenetics, and CLARITY for the Stanford Big Data 2015

Gradinaru/Newman Collaboration Yields 3D View of Bacterial Infection by MiPACT tissue clearing [Video] [Caltech Press Release]

Scientific American 10 World Changing Ideas 2014 features our group's work on Transparent Organisms

CBS News on "Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell, 2014"

The World Economic Forum Blog: Interview about Optogenetics and CLARITY

Short Version: TEDxCaltech: The Brain, January 2013

Long Version: Watson Richard C. Biedebach Memorial Lecture, December 2012 (Available on iTunes U)

Positions currently available

Please email your CV and a cover page detailing your future research or position type interests to Dr. Viviana Gradinaru (viviana@caltech.edu).

Gradinaru Lab News

09/2016

We collaborated with the Newman lab for Microbial Imaging after PACT - "Exposing the 3D biogeography and metabolic states of pathogens in cystic fibrosis sputum via hydrogel embedding, clearing and rRNA labeling". Paper here.

07/2016

Jenny's review on tissue clearing and viral vectors for mapping biological circuits is now in Current Opinion in Biotechnology.

04/2016

Cheng's paper out in Neuron!

02/2016

Viviana is awarded a PECASE!: "Presidential Early Career Awards for Scientists and Engineers, the highest honor bestowed by the United States Government on science and engineering professionals in the early stages of their independent research careers."

02/2016

Ben's paper out in Nature Biotechnology on Delivering genes across the blood-brain barrier

01/2016

Nature News and Views on Optogenetic Voltage Sensors

10/2015

If you use tissue clearing - these detailed protocols just out in Nature Protocols will help!

07/2015

Spying on Opsins.

03/2015

Viviana is a Sloan Fellow in Neuroscience.

10/2014

Glab is awarded a BRAIN initiative grant in collaboration with Changhuei Yang's group at Caltech.

9/2014

Viviana is elected to the Allen Brain Institute Next Generation Leaders Council.

9/2014

Nick and Claire's paper on voltage sensing with Archer 1 has been published in Nature Communications.

8/2014

Glab's first paper has been published in Cell.

Old News Archive

Life in the GLab

03/2015

Uninspired? On Creative Work.

04/2013

Picture of the Month!

04/2013

Lindsay and Jenny performed the first in vivo electrophysiology experiment with optogenetics.

02/2013

Happy birthday, Claire!

Archive