Barton Group Publications

    2022

  • "Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase", L. E. Salay, A. Blee, M. K. Raza, K. Gallagher, H. Chen, A. Dorfeuille, J. K. Barton, W. Chazin, Biochemistry, in press (2022).
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    2021

  • "The [4Fe4S] Cluster of Yeast DNA Polymerase e is Redox Active and can undergo DNA-mediated Signaling", M.N. Pinto, J. ter Beek, L.A. Ekanger, E. Johansson, and Jacqueline K. Barton, Journal of the American Chemical Society, 143, (2021).
  • "DNA Electrochemistry: Charge Transport Pathways through DNA Films on Gold", Adela Nano, Ariel L. Furst, Michael G. Hill, and Jacqueline K. Barton, Journal of the American Chemical Society, 143, 11631-40 (2021).
  • "Rhodium Complexes Targeting DNA Mismatches As a Basis for New Therapeutics in Cancers Deficient in Mismatch Repair", Adela Nano, Joanne Dai, Julie Bailis, and Jacqueline K. Barton, Biochemistry, 60, 2055-63 (2021).
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    2020

  • "Extracellular DNA promotes efficient extracellular electron transfer by pyocyanin in Pseudomonas aeruginosa biofilms”, S.H. Saunders, E.C.M. Tse, M.D. Yates, F.J. Otero, S.A. Trammell, E.D.A. Stemp, J.K. Barton, L.M. Tender, and D.K. Newman, Cell2020, 182, 4, 919-932Abstract
  • "In vivo Anticancer Activity of a Rhodium Metalloinsertor in the HCT116 Xenograft Tumor Model”, S. Threatt, T. Synold, J. Wun, and J.K. Barton, PNAS2020, 117 (30), 17535-17542. Abstract.
  •  "UvrC Coordinates an O2Sensitive [4Fe4S] Cofactor", R.M.B. Silva, M.A. Grodick, and J.K. Barton, JACS2020, 142, 25, 10964–10977. Abstract
  • "Cell-Selective Cytotoxicity of a Fluorescent Rhodium Metalloinsertor Conjugate Results from Irreversible DNA Damage at a Base Pair Mismatch", A. Nano, J. Bailis, N. Mariano, E. Pham, S. Threatt, and J.K. Barton, Biochemistry, 2020, 59, 717-726Abstract
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    2019

  • "Redox Chemistry in the Genome: Emergence of the [4Fe4S] Cofactor in DNA Repair and Replication" J.K. Barton, R.M.B. Silva, and E. O'Brien, Annual Reviews, 2019, 88, 163-190. PMID: 31220976Abstract.
  • "Cellular Target of a Rhodium Metalloinstertor is the DNA Base Pair Mismatch" K.M. Boyle, A. Nano, C. Day, and J.K. Barton Chemistry European Journal, 2019, 25, 1-7. PMID: 30615818Abstract.
  • "Effective Distance for DNA-Mediated Charge Transport between Repair Proteins" E.C.M. Tse, T.J. Zwang, S. Bedoya, J.K. Barton ACS Central Science, 2019, 5 (1), 65-72. PMCID# PMC6346725Abstract.
  • 2018

  • "Nitric Oxide Modulates Endonuclease III Redox Activity by a 800 mV Negative Shift upon [4Fe4S] Cluster Nitrosylation" L. A. Ekanger, P. H. Oyala, A. Moradian, M. J. Sweredoski, and J.K. Barton JACS, 2018, 140 (37), 11800-11810. Abstract.
  • "Substrate Binding Regulates Redox Signaling in Human DNA Primase"E. O'Brien, M.E. Holt, L.E. Salay, W.J. Chazin, and J.K. Barton JACS, 140 (39), 17153-17162 2018 PMID:3043374 Abstract.
  • "Yeast Require Redox Switching in DNA Primase" E. O'Brien, L.E. Salay, E.A. Epum, K.L. Friedman, W.J. Chazin, and J.K. Barton PNAS, PMID: 30541886 (2018) Abstract.
  • "Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs"M.E. Holt, L.E. Salay, E. O'Brien, J.K. Barton, and W.J. Chazin PLOS One, PMID: 30562384 (2018) Abstract.
  • "A Human MUTYH Variant Linking Colonic Polyposis to Redox Degradation of the [4Fe4S]2+ Cluster"K. McDonnell, J. Chemler, P.L. Bartels, E. O'Brien, M. Marvin, J. Ortega, R. Stern, L. Raskin, G. Li, D. Sherman, J.K. Barton, and S. Gruber Nature Chemistry, 10, 873-880 (2018) Abstract.
  • "Sensing DNA through DNA Charge Transport" T.J. Zwang, E.C.M. Tse, J.K. Barton ACS Chemical Biology, 13, 1799-1809 (2018) Abstract.
  • "A Family of Rhodium Complexes with Selective Toxicity toward Mismatch Repair-Deficient Cancers" K.M. Boyle, J.K. Barton JACS, 140, 16, 5612-5624 (2018) Abstract.
  • "A Compass at Weak Magentic Fields Using Thymine Dimer Repair" T.J. Zwang, E.C.M. Tse, D. Zhong, J.K. Barton ACS Cent. Sci, 4, 405-412 (2018)
  • "Targeting DNA Mismatches with Coordination Complexes" J.K. Barton, A.N. Boynton, K.M. Boyle, Chapter 14 in DNA-targeting Molecules as Therapeutic Agents, Ed. M.J. Waring, The Royal Society of Chemistry; 2018, 367-390

    2017

  • "A Redox Role for the [4Fe-4S] Cluster of Yeast DNA Polymerase δ" P.L. Bartels, J.L. Stodola, P.M.J. Burgers, J.K. Barton JACS, 139, 50, 18339-18348 (2017) Abstract.
  • "A rhodium-cyanine fluorescent probe: detection and signaling of mismatches in DNA" A. Nano, A.N. Boynton, J.K. Barton JACS, 139, 48, 17301-17304 (2017) Abstract.
  • "DNA Signaling by Iron-Sulfur Cluster Proteins" P.L. Bartels, E. O'Brien, J.K. Barton Iron-Sulfur Clusters in Chemistry and Biology (ed. T. Rouault, de Gruyter, Berlin/Boston), 2, 405-423 (2017) Abstract.
  • "The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins" E.C.M. Tse, T.J. Zwang, J.K. Barton JACS, 139, 36, 12784-12792 (2017) Abstract.
  • "Sulfur K-Edge XAS Studies of the Effect of DNA Binding on the [Fe4S4] Site in EndoIII and MutY" Y. Ha, A.R. Arnold, N.N. Nuñez, P.L. Bartels, A. Zhou, S.S. David, J.K. Barton, B. Hedman, K.O. Hodgson, E.I. Solomon JACS, 139, 33, 11434-11442 (2017) Abstract.
  • "A Ruthenium(II) Complex as a Luminescent Probe for DNA Mismatches and Abasic Sites" A. N. Boynton, L. Marcélis, A.J. McConnell, J.K. Barton, Inorg. Chem., 56, 14, 8381-8389 (2017) Abstract.
  • "Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells" J. M. Bailis, A. G. Weidmann, N.F. Mariano, J.K. Barton, PNAS, 114, 27, 6948-6953 (2017). Abstract.
  • "Electrical Probes of DNA-Binding Proteins" J.K. Barton, P.L. Bartels, Y. Deng, E. O'Brien, p. 355-414 in Methods in Enzymology Academic Press, 591, (2017). Abstract.
  • "Two-Electrode Platforms for Protein Biosensing Based on Charge Transport through the DNA Double Helix" A. L. Furst, M. G. Hill, and J.K. Barton, p. 1-25 in Electroanalytical Chemistry:Advanced Series CRC Press, 27, Ed. A. Bard (2017). Link.
  • "Electrochemistry of the [4Fe4S] Cluster in Base Excision Repair Proteins: Tuning the Redox Potential with DNA", Phillip L. Bartels, Andy Zhou, Anna R. Arnold, Nicole N. Nuñez, Frank N. Crespilho, Sheila S. David, and Jacqueline K. Barton Langmuir, 33, 2523-2530 (2017) Abstract.
  • "The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport", E. O'Brien, M.E. Holt, M.K. Thompson, L.E. Salay, A.C. Ehlinger, W.J. Chazin, J.K. Barton, Science, 355, 813 (2017). Abstract. Full Text.
  • 2016

  • "Helix-Dependent Spin Filtering through the DNA Duplex", Theodore J. Zwang, Sylvia Hürlimann, Michael G. Hill, and Jacqueline K. Barton J. Am. Chem. Soc. 138 15551-15554 (2016). Abstract.
  • "Redox Signaling through DNA", Elizabeth O'Brien, Rebekah M. B. Silva, and Jacqueline K. Barton Israel J. Chem. 56, 705-723 (2016). Abstract.
  • "Characterization of the DNA-Mediated Oxidation of DPS, A Bacterial Ferritin", Anna Arnold, Andy Zhou, and Jacqueline K. Barton J. Am. Chem. Soc. 138, 11290-11298 (2016). Abstract.
  • "Targeting DNA mismatches with rhodium metalloinserters", Kelsey M. Boyle, and Jacqueline K. Barton Inorg. Chim. Acta 452, 3-11 (2016). Abstract.
  • "[Ru(Me4phen)2(dppz)]2+, a Light Switch for DNA Mismatches", Adam N. Boynton, Lionel Marcélis, and Jacqueline K. Barton, J. Am. Chem. Soc. 138, 5020-5023 (2016). Abstract.
  • "DNA Charge Transport: from Chemical Principles to the Cell", Anna R. Arnold, Michael A. Grodick, and Jacqueline K. Barton, Cell Chemical Biology 23, 183-197(2016). Abstract.
  • 2015

  • "DNA Sensors Using DNA Charge Transport Chemistry" J. K. Barton, A. L. Furst, and M. A. Grodick, p. 105-120 in DNA in Supramolecular Chemistry and Nanotechnology , E. Stultz and G. H. Clever, ed. Wiley (2015). Abstract.
  • "A Monofunctional Platinum Complex Coordinated to a Rhodium Metalloinsertor Binds Mismatched DNA in the Minor Groove" A. G. Weidmann and J. K. Barton Inorganic Chemistry 54 9626-9636(2015). Abstract.
  • "DNA Electrochemistry shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors" A. L. Furst and J. K. Barton Chemistry and Biology 22 938(2015). Abstract.
  • "A Multiplexed, Two-Electrode Platform for Biosensing Based on DNA-Mediated Charge Transport" A. L. Furst, Michael G. Hill, and J. K. Barton Langmuir 31 6554-6562(2015). Abstract.
  • "DNA Charge Transport within the Cell" M. A. Grodick, N. B. Muren, and J. K. Barton Biochemistry 54 962-973(2015). Abstract.
  • "Oxidation of p53 through DNA Charge Transport Involves a Network of Disulfides within the DNA-Binding Domain" K. N. Schaefer, W. M. Geil, M. J. Sweredoski, A. Moradian, S. Hess, and J. K. Barton Biochemistry 54 932-941(2015). Abstract.
  • 2014

  • "Electrocatalysis in DNA Sensors" A. L. Furst, M. G. Hill and J. K. Barton Polyhedron 84 150-159(2014). Abstract.
  • "Targeted Chemotherapy with Metal Complexes" A. G. Weidmann, A. C. Komor and J. K. Barton Comments Mod Chem A Comments Inorg. Chem. 34 114(2014). Abstract.
  • "An Unusual Ligand Coordination Gives Rise to a New Family of Rhodium Metalloinsertors with Improved Selectivity and Potency" A. C. Komor and J. K. Barton J. Am. Chem. Soc. 136 14160-14712(2014). Abstract.
  • "Label-free electrochemical detection of human methyltransferase from tumors" A. L. Furst, N. B. Muren, M. G. Hill and J. K. Barton Proc. Natl. Acad. Sci. USA 111 14985-14989(2014). Abstract.
  • "Construction and Application of a RhÐPt DNA Metalloinsertor Conjugate" A. G. Weidmann and J. K. Barton Inorg. Chem. 53 7812-7814(2014). Abstract.
  • "DNA-Mediated Oxidation of p53" K. N. Schaefer and J. K. Barton Biochemistry 53 3467-3475(2014). Abstract.
  • "DNA-Mediated Signaling by Proteins with 4Fe-4S Clusters Is Necessary for Genomic Integrity" M. A. Grodick, H. M. Segal, T. J. Zwang and J. K. Barton J. Am. Chem. Soc. 136 6470-6478(2014). Abstract.
  • 2013

  • "DNA-Modified Electrodes Fabricated Using Copper-Free Click Chemistry for Enhanced Protein Detection" A. L. Furst, M. G. Hill and J. K. Barton Langmuir 29 16141(2013). Abstract.
  • "Electrochemical Patterning and Detection of DNA Arrays on a Two-Electrode Platform" A. L. Furst, S. Landfield, M. G. Hill and J. K. Barton J. Am. Chem. Soc. 135 19099(2013). Abstract.
  • "An Inducible, Isogenic Cancer Cell Line System for Targeting the State of Mismatch Repair Deficiency" J. M. Bailis, M. L. Gordon, J. L. Gurgel, A. C. Komor, J. K. Barton and I. R. Kirsch PLOS ONE 8 e78726(2013) Abstract.
  • "Luminescence of [Ru(bpy)2(dppz)]2+ Bound to RNA Mismatches" A. J. McConnell, H. G. Song and J. K. Barton Inorg. Chem. 52 10131(2013). Abstract.
  • "DNA Protection by the Bacterial Ferritin Dps via DNA Charge Transport" A. R. Arnold and J. K. Barton J. Am. Chem. Soc. 135 15726(2013). Abstract.
  • "Electrochemical Assay for the Signal-On Detection of Human DNA Methyltransferase Activity" N. B. Muren and J. K. Barton J. Am. Chem. Soc. 135 16632(2013). Abstract.
  • "Intraduplex DNA-Mediated Electrochemistry of Covalently Tethered Redox-Active Reporters" C. G. Pheeney and J. K. Barton J. Am. Chem. Soc. 135 14944(2013). Abstract.
  • "Multiplexed Electrochemistry of DNA-Bound Metalloproteins" C. G. Pheeney, A. R. Arnold, M. A. Grodick and J. K. Barton J. Am. Chem. Soc. 135 11869(2013). Abstract.
  • "Biological effects of simple changes in functionality on rhodium metalloinsertors" A. G. Weidmann, A. C. Komor and J. K. Barton Philosophical Transactions of the Royal Society A 371 20120177(2013). Abstract.
  • "The path for metal complexes to a DNA target" A. C. Komor and J. K. Barton Chem. Commun. 49 3617-3630(2013). Abstract.
  • 2012

  • "Luminescent Properties of Ruthenium(II) Complexes with Sterically Expansive Ligands Bound to DNA Defects" A. J. McConnell , M. H. Lim , E. D. Olmon , H. Song , E. E. Dervan , and J. K. Barton Inorg. Chem. 51 12511-12520(2012). Abstract.
  • "Cell-Selective Biological Activity of Rhodium Metalloinsertors Correlates with Subcellular Localization" A. C. Komor , C. J. Schneider , A. G. Weidmann , and J. K. Barton J. Am. Chem. Soc. 134 19223-19233(2012). Abstract.
  • "Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport" N. B. Muren, E. D. Olmon and J. K. Barton Phys. Chem. Chem. Phys. 14 13754-13771(2012). Abstract.
  • "DNA Charge Transport for Sensing and Signaling" P. A. Sontz, N. B. Muren and J. K. Barton Acc. Chem. Res. 1792-1800(2012). Abstract.
  • "Crystal structure of delta-[Ru(bpy)2(dppz)]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation" H. Song, J. T. Kaiser and J. K. Barton Nat. Chem. 4 615-620 (2012). Abstract.
  • "DNA sensing by electrocatalysis with hemoglobin" C. G. Pheeney, L. F. Guerra and J. K. Barton Proc. Natl. Acad. Sci. 109 11528-11533 (2012). Abstract.
  • "DNA Electrochemistry with Tethered Methylene Blue" C. G. Pheeney and J. K. Barton Langmuir 28 7063-7070 (2012). Abstract.
  • "DNA charge transport as a first step in coordinating the detection of lesions by repair proteins" P. A. Sontz, T. P. Mui, J. O. Fuss, J. A. Tainer, and J. K. Barton Proc. Natl. Acad. Sci. 109 1856-1861 (2012). Abstract.
  • "Transducing methyltransferase activity into electrical signals in a carbon nanotube-DNA device" H. Wang, N. B. Muren, D. Ordinario, A. A. Gorodetsky, J. K. Barton and C. Nuckolls , Chem. Sci. 3 62-65 (2012). Abstract.
  • 2011

  • "Using Metal Complex Reduced States to Monitor the Oxidation of DNA" E. D. Olmon, M. G. Hill, and J. K. Barton, Inorg. Chem. 50(23), 12034-12044 (2011). Abstract.
  • "Selective Cytotoxicity of Rhodium Metalloinsertors in Mismatch Repair-Deficient Cells" R. J. Ernst, A. C. Komor, and J. K. Barton, Biochemistry 50(50), 10919-10928 (2011). Abstract.
  • "ATP-Stimulated, DNA-Mediated Redox Signaling by XPD, a DNA Repair and Transcription Helicase" T. P. Mui, J. O. Fuss, J. P. Ishida, J. A. Tainer, and J. K. Barton, J. Am. Chem. Soc. 133(41), 16378-16381 (2011). Abstract.
  • "Charge Photoinjection in Intercalated and Covalently Bound [Re(CO)3(dppz)(py)]+-DNA Constructs Monitored by Time-Resolved Visible and Infrared Spectroscopy" E. D. Olmon, P. A. Sontz, A. M. Blanco-Rodriguez, M. Towrie, I. P. Clark, A. Vicek Jr., and J. K. Barton, J. Am. Chem. Soc. 133(34), 13718-13730 (2011). Abstract.
  • "Mutants of the Base Excision Repair Glycosylase, Endonuclease III: DNA Charge Transport as a First Step in Lesion Detection" C. A. Romano*, P. A. Sontz*, and J. K. Barton, Biochemistry 50(27), 6133-6145 (2011). Abstract.
  • "Single-Step Charge Transport through DNA over Long Distances" J. C. Genereux, S. M. Wuerth, and J. K. Barton, J. Am. Chem. Soc. 133(11), 3863-3868 (2011). Abstract.
  • "Metal complexes for DNA-mediated charge transport" J.K. Barton, E. D. Olmon and P. A. Sontz, Coordination Chemistry Reviews 255, 619-634 (2011). Abstract.
  • "DNA charge transport over 34 nm" J. D. Slinker, N. B. Muren, S. E. Renfrew, and J. K. Barton, Nat. Chem. 3, 230-235 (2011). Abstract.
  • 2010

  • "Targeting a ruthenium complex to the nucleus with short peptides" C.A. Puckett and J. K. Barton, Bioorg. Med. Chem. 18, 3564–3569 (2010). Abstract.
  • "DNA-Mediated Electron Transfer in Naphthalene-Modified Oligonucleotides" M. Tanaka, B. Elias, and J. K. Barton, J. Org. Chem. 75(8), 2423–2428 (2010). Abstract.
  • "Multiplexed DNA-Modified Electrodes" J.D. Slinker, N.B. Muren, A.A. Gorodetsky, and J.K. Barton, J. Am. Chem. Soc. 132(8), 2769-2774 (2010). Abstract.
  • "Mechanisms for DNA Charge Transport" J.G. Genereux and J.K. Barton, Chem. Rev. 110(3), 1642-1662 (2010). Abstract.
  • "Exploring the cellular accumulation of metal complexes" C.A. Puckett, R.J. Ernst, and J.K. Barton, Dalton Trans. 39, 1159-1170 (2010). Abstract.
  • "DNA-Mediated Charge Transport in Redox Sensing and Signaling" J.C. Genereux, A.K. Boal, and J.K. Barton, J. Am. Chem. Soc. 132(3), 891-905 (2010). Abstract.
  • 2009

  • "Redox signaling between DNA repair proteins for efficient lesion detection" A.K. Boal, J.C. Genereux, P.A. Sontz, J.A. Gralnick, D.K. Newman, and J.K. Barton, Proc. Natl. Acad. Sci. USA 106(36), 15237-15242 (2009). Abstract.
  • "DNA-mediated redox signaling for transcriptional activation of SoxR" P.E. Lee, B. Demple, and J.K. Barton, Proc. Natl. Acad. Sci. USA 106(32), 13164-13168 (2009). Abstract.
  • "Fluorescein Redirects a Ruthenium-Octaarginine Conjugate to the Nucleus" C.A. Puckett and J.K. Barton, J. Am. Chem. Soc. 131(25), 8738-8739 (2009). Abstract.
  • "Sensitivity of Ru(bpy)2dppz2+ Luminescence to DNA Defects" M.H. Lim, H. Song, E.D. Olmon, E.E. Dervan, and J.K. Barton, Inorganic Chemistry 48, 5392-5397 (2009). Abstract.
  • "Molecular Electronics: DNA Charges Ahead" J.C. Genereux and J.K. Barton, Nature Chemistry 1, 106-107 (2009). Abstract.
  • "A Bulky Rhodium Complex Bound to an Adenosine-Adenosine DNA Mismatch: General Architecture of the Metalloinsertion Binding Mode" B.M. Zeglis, V.C. Pierre, J.T. Kaiser, and J.K. Barton, Biochemistry 48, 4247-4253 (2009). Abstract.
  • "DNA Mismatch Binding and Antiproliferative Activity of Rhodium Metalloinsertors" R.J. Ernst, H. Song, and J.K. Barton, J. Am. Chem. Soc. 131, 2359-2366 (2009). Abstract.
  • "Recognition of Abasic Sites and Single Base Bulges in DNA by a Metalloinsertor" B.M. Zeglis, J.A. Boland, and J.K. Barton, Biochem. 48, 839-849 (2009). Abstract.
  • "Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport" E.J. Merino, M.L. Davis, and J.K. Barton, Biochem. 48, 660-666 (2009). Abstract.
  • 2008

  • "DNA-mediated Electrochemistry" A.A. Gorodetsky, M.C. Buzzeo, and J.K. Barton, Bioconj. Chem. 19, 2285-2296 (2008). Abstract.
  • "Ping-Pong Electron Transfer through DNA" B. Elias, J.C. Genereux, and J.K. Barton, Angew. Chem. Int. Ed. 47, 9067-9070 (2008). Abstract.
  • "Scanning Electrochemical Microscopy of DNA Monolayers Modified with Nile Blue " A.A. Gorodetsky, W.J. Hammond, M.G. Hill, K. Slowinski, and J.K. Barton, Langmuir 24, 14282-14288 (2008). Abstract.
  • "Redmond Red as a Redox Probe for the DNA-Mediated Detection of Abasic Sites " M.C. Buzzeo and J.K. Barton, Bioconj. Chem. 19, 2110-2112 (2008). Abstract.
  • "Back-Electron Transfer Suppresses the Periodic Length Dependence of DNA-Mediated Charge Transport across Adenine Tracts " J.C. Genereux, K.E. Augustyn, M.L. Davis, F. Shao, and J.K. Barton, J. Am. Chem. Soc. 130, 15150-15156 (2008). Abstract.
  • "Mechanism of Cellular Uptake of a Ruthenium Polypyridyl Complex " C.A. Puckett and J.K. Barton, Biochem. 47, 11711-11716 (2008). Abstract.
  • "Binding of Ru(bpy)2(eilatin)2+ to Matched and Mismatched DNA " B.M. Zeglis and J.K. Barton, Inorg. Chem. 47, 6452-6457 (2008). Abstract.
  • "Targeting Abasic Sites and Single Base Bulges in DNA with Metalloinsertors" B.M. Zeglis, J.A. Boland, and J.K. Barton, J. Am. Chem. Soc. 130, 7530-7531 (2008). Abstract.
  • "Biological Contexts for DNA Charge Transport Chemistry" E.J. Merino, A.K. Boal, and J.K. Barton, Curr. Op. Chem. Biol. 12, 229-237 (2008). Abstract.
  • "Electrical Detection of TATA Binding Protein at DNA-Modified Microelectrodes" A.A. Gorodetsky, A. Ebrahim, and J.K. Barton, J. Am. Chem Soc. 130, 2924-2925 (2008). Abstract.
  • "DNA binding shifts the redox potential of the transcription factor SoxR" A.A. Gorodetsky, L.E.P. Dietrich, P.E. Lee, B. Demple, D.K. Newman, and J.K. Barton, Proc. Natl. Acad. Sci. USA 105, 3684-3689 (2008). Abstract.
  • "Conductivity of a single DNA duplex bridging a carbon nanotube gap" X. Guo, A.A. Gorodetsky, J. Hone, J.K. Barton, and C. Nuckolls, Nat. Nanotech. 3, 163-167 (2008). Abstract.
  • "DNA Oxidation by Charge Transport in Mitochondria" E.J. Merino and J.K. Barton, Biochem. 47, 1511-1517 (2008). Abstract.
  • "Charge Migration along the DNA Duplex: Hole versus Electron Transport" B. Elias, F. Shao, and J.K. Barton, J. Am. Chem. Soc. 130, 1152-1153 (2008). Abstract.
  • 2007

  • "A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance" K.E. Augustyn, E.J. Merino, and J.K. Barton, Proc. Natl. Acad. Sci. USA 104, 18907-18912 (2007). Abstract.
  • "Long-Range Electron and Hole Transport through DNA with Tethered Cyclometalated Iridium(III) Complexes" F. Shao and J.K. Barton, J. Am. Chem. Soc. 129, 14733-14738 (2007). Abstract.
  • "Synthesis and Characterization of Iridium(III) Cyclometalated Complexes with Oligonucleotides: Insights into Redox Reactions with DNA" F. Shao, B. Elias, W. Lu and J.K. Barton, Inorg. Chem. 46, 10187-10199 (2007). Abstract.
  • "DNA Strand Cleavage near a CC Mismatch Directed by a Metalloinsertor" M.H. Lim, I.H. Lau, and J.K. Barton, Inorg. Chem. 46, 9528-9530 (2007). Abstract.
  • "Charge Separation in a Ruthenium-Quencher Conjugate Bound to DNA" K.E. Augustyn and J.K. Barton, Inorg. Chem. 46, 9337-9350 (2007). Abstract.
  • "Metallo-intercalators and metallo-insertors" B.M. Zeglis, V. C. Pierre, and J.K. Barton, Chem. Comm. 2007, 4565-4579 (2007). Abstract.
  • "DNA repair glycosylases with a [4Fe–4S] cluster: A redox cofactor for DNA-mediated charge transport?" A.K. Boal, E. Yavin, and J.K. Barton, J. Inorg. Biochem. 101, 1913-1921 (2007). Abstract.
  • "Insertion of a Bulky Rhodium Complex into a DNA Cytosine-Cytosine Mismatch: An NMR Solution Study" C. Cordier, V. C. Pierre, and J.K. Barton, J. Am. Chem. Soc. 129, 12287-12295 (2007). Abstract.
  • "Coupling into the Base Pair Stack is Necessary for DNA-mediated Electrochemistry" A.A. Gorodetsky, O. Green, E. Yavin, and J.K. Barton, Bioconj. Chem. 18, 1434-1441 (2007). Abstract.
  • "Distance-independent DNA Charge Transport across an Adenine Tract" K.E. Augustyn, J.C. Genereux, and J.K. Barton, Angew. Chem. Int. Ed. 46, 5731-5733 (2007). Abstract.
  • "Inorganic-Organic Hybrid Luminescent Binary Probe for DNA Detection Based on Spin-Forbidden Resonance Energy Transfer" A.A. Martí, C.A. Puckett, J. Dyer, N. Stevens, S. Jockusch, J. Ju, J.K. Barton, and N.J. Turro,J. Am. Chem. Soc. 129, 8680-8681 (2007). Abstract.
  • "DNA-mediated Electrochemistry of Disulfides on Graphite" A.A. Gorodetsky and J.K. Barton, J. Am. Chem. Soc. 129, 6074-6075 (2007). Abstract.
  • "DNA Base Mismatch Detection with Bulky Rhodium Intercalators: Synthesis and Applications" B.M. Zeglis and J.K. Barton, Nat. Prot. 2, 357-371 (2007). Abstract.
  • "Oxidation by DNA Charge Transport Damages Conserved Sequence Block II, a Regulatory Element in Mitochondrial DNA" E.J. Merino and J.K. Barton, Biochem. 46, 2805-2811 (2007). Abstract.
  • "Differential Ionic Permeation of DNA-modified Electrodes" D.M. Ceres, A.K. Udit, H.D. Hill, M.G. Hill, and J.K. Barton, J. Phys. Chem. B 111, 663-668 (2007). Abstract.
  • "Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator" V.C. Pierre, J.T. Kaiser and J.K. Barton, Proc. Natl. Acad. Sci. USA 104, 429-434 (2007). Abstract.
  • "Methods to Explore Cellular Uptake of Ruthenium Complexes" C.A. Puckett and J.K. Barton, J. Am. Chem. Soc. 129, 46-47 (2007). Abstract.
  • 2006

  • "DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators " J.R. Hart, O. Glebov, R.J. Ernst, I.R. Kirsch, and J.K. Barton, Proc. Natl. Acad. Sci. USA 103, 15359-15363 (2006). Abstract.
  • "Targeting DNA Mismatches with Rhodium Intercalators Functionalized with a Cell-Penetrating Peptide" J. Brunner and J.K. Barton, Biochem. 45, 12295-12302 (2006). Abstract.
  • "Direct Electrochemistry of Endonuclease III in the Presence and Absence of DNA" A.A. Gorodetsky, A.K. Boal, and J.K. Barton, J. Am. Chem. Soc. 128, 12082-12083 (2006). Abstract.
  • "Electrochemistry Using Self-Assembled DNA Monolayers on Highly Oriented Pyrolytic Graphite" A.A. Gorodetsky and J.K. Barton, Langmuir 22, 7917-7922 (2006). Abstract.
  • "Site-Specific DNA Photocleavage by Rhodium Intercalators Analyzed by MALDI-TOF Mass Spectrometry" J. Brunner and J.K. Barton, J. Am. Chem. Soc. 128, 6772-6773 (2006). Abstract.
  • "Electron Trap for DNA-bound Repair Enzymes: A Strategy For DNA-mediated Signaling" E. Yavin, E.D.A. Stemp, V.L. O'Shea, S.S. David and J.K. Barton, Proc. Nat. Acad. Sci. USA 103, 3610-3614 (2006). Abstract.
  • "A Mismatch-Selective Bifunctional Rhodium-Oregon Green Conjugate: A Fluorescent Probe for Mismatched DNA" B.M. Zeglis and J.K. Barton, J. Am. Chem. Soc. 128, 5654-5655 (2006). Abstract.
  • 2005

  • "Sequence Dependence of Charge Transport through DNA Domains" F. Shao, K. Augustyn and J.K. Barton, J. Am. Chem. Soc. 127, 17445-17452 (2005). Abstract.
  • "Reductive and Oxidative DNA Damage by Photoactive Platinum(II) Intercalators" W. Lu, D.A. Vicic, and J.K. Barton, Inorg. Chem. 44, 7970-7980 (2005). Abstract.
  • "DNA Charge Transport Leading to Disulfide Bond Formation" T. Takada and J.K. Barton, J. Am. Chem. Soc. 127, 12204-12205 (2005). Abstract.
  • "Electrochemically Monitoring DNA Repair by Photolyase" M.C. DeRosa, A. Sancar, and J.K. Barton, Proc. Nat. Acad. Sci. USA 102, 10788-10792 (2005). Abstract.
  • "Sequence-Dependent DNA Dynamics: The Regulator of DNA-Mediated Charge Transport" M.A. O'Neill and J.K. Barton, in Charge Transfer in DNA: From Mechanism to Application, ed. H.-A. Wagenknecht, Wiley-VCH, pp. 27-75 (2005).
  • "DNA Electrochemistry through the Base Pairs Not the Sugar-Phosphate Backbone" T. Liu and J.K. Barton, J. Am. Chem. Soc. 127, 10160-10161 (2005). Abstract.
  • "DNA-Bound Redox Activity of DNA Repair Glycosylases Containing [4Fe-4S] Clusters" A.K. Boal, E. Yavin, O.A. Lukianova, V.L. O'Shea, S.S. David, and J.K. Barton, Biochem. 44, 8397-8407 (2005). Abstract.
  • "Electrochemical Detection of Lesions in DNA " A.K. Boal and J.K. Barton, Bioconj. Chem. 16, 312-321 (2005). Abstract.
  • "Protein-DNA Charge Transport: Redox Activation of a DNA Repair Protein by Guanine Radical" E. Yavin, A.K. Boal, E.D.A. Stemp, E.M. Boon, A.L. Livingston, V.L. O'Shea, S.S. David, and J.K. Barton, Proc. Nat. Acad. Sci. USA 102, 3546-3551 (2005). Abstract.
  • 2004

  • "Long-Range Oxidative Damage to Cytosines in Duplex DNA " F.W. Shao, M.A. O'Neill, and J.K. Barton, Proc. Nat. Acad. Sci. USA 101, 17914-17919 (2004). Abstract.
  • "Electron Transfer Rates in DNA Films as a Function of Tether Length" T.G. Drummond, M.G. Hill, and J.K. Barton, J. Am. Chem. Soc. 126, 15010-15011 (2004). Abstract.
  • "Tuning the DNA Reactivity of cis-Platinum: Conjugation to a Mismatch-Specific Metallointercalator" A. Petitjean and J.K. Barton, J. Am. Chem. Soc. 126, 14728-14729 (2004). Abstract.
  • "SNP Discovery by Targeted DNA Photocleavage" J.R. Hart, M.D. Johnson, and J.K. Barton, Proc. Nat. Acad. Sci. USA 101, 14040-14044 (2004). Abstract.
  • "DNA-Mediated Charge Transport Requires Conformational Motion of the DNA Bases: Elimination of Charge Transport in Rigid Glasses at 77 K" M.A. O'Neill and J.K. Barton, J. Am. Chem. Soc. 126, 13234-13235 (2004). Abstract.
  • "DNA Charge Transport: Conformationally Gated Hopping through Stacked Domains" M.A. O'Neill and J.K. Barton, J. Am. Chem. Soc. 126, 11471-11483 (2004). Abstract.
  • "Charge Equilibration Between Two Distinct Sites in Double Helical DNA" S. Delaney, J. Yoo, E.D.A. Stemp, and J.K. Barton, Proc. Nat. Acad. Sci. USA 101, 10511-10516 (2004). Abstract.
  • "[Ru(bpy)2(L)]Cl2: Luminescent Metal Complexes that Bind DNA Base Mismatches" E. Rüba, J.R. Hart, and J.K. Barton, Inorg. Chem. 43, 4570-4578 (2004). Abstract.
  • "Bifunctional Rhodium Intercalator Conjugates as Mismatch-Directing DNA Alkylating Agents" U. Schatzschneider and J.K. Barton, J. Am. Chem. Soc. 126, 8630-8631 (2004). Abstract.
  • "Effects of the Photooxidant on DNA-Mediated Charge Transport" T.T. Williams, C. Dohno, E.D.A. Stemp, and J.K. Barton, J. Am. Chem. Soc. 126, 8148-8158 (2004). Abstract.
  • "Direct Chemical Evidence for Charge Transfer between Photoexcited 2-Aminopurine and Guanine in Duplex DNA" M.A. O'Neill, C. Dohno, and J.K. Barton, J. Am. Chem. Soc. 126, 1316-1317 (2004). Abstract.
  • "DNA-mediated Charge Transport Chemistry and Biology" M.A. O'Neill and J.K. Barton, in Topics in Current Chemistry: Electron Transfer in DNA: I, ed. Schuster, Springer-Verlag, pp. 67-115 (2004). Abstract.
  • 2003

  • "1H NMR Studies of Nickel(II) Complexes Bound to Oligonucleotides: A Novel Technique for Distinguishing the Binding Locations of Metal Complexes in DNA" P.K. Bhattacharya, H.J. Lawson, and J.K. Barton, Inorg. Chem. 42, 8811-8817 (2003). Abstract.
  • "Ultrafast Dynamics in DNA-Mediated Electron Transfer: Base Gating and the Role of Temperature" M.A. O'Neill, H.-C. Becker, C. Wan, J.K. Barton, and A.H. Zewail, Angew. Chem. Int. Ed. 42, 5896-5900 (2003).
  • "In Situ Scanning Tunneling Microscopy of DNA-Modified Gold Surfaces: Bias and Mismatch Dependence" D.M. Ceres and J.K. Barton, J. Am. Chem. Soc. 125, 14964-14965 (2003). Abstract.
  • "Charge Transport in DNA Duplex/Quadruplex Conjugates" S. Delaney and J.K. Barton, Biochemistry 42, 14159-14165 (2003). Abstract.
  • "DNA Electrochemistry as a probe of base pair stacking in A-, B-, and Z-form DNA" E.M. Boon and J.K. Barton, Bioconjugate Chem. 14, 1140-1147 (2003). Abstract.
  • "Reduction of Ferricyanide by Methylene Blue at a DNA-Modified Rotating-Disk Electrode" E. M. Boon, J.K. Barton, V. Bhaghat, M. Nerissian, W. Wang, and M.G. Hill, Langmuir 19, 9255-9259 (2003). Abstract.
  • "Intercalative Stacking: A Critical Feature of DNA Charge-Transport Electrochemistry" E.M. Boon, N.M. Jackson, M.D. Wightman, S.O. Kelley, M.G. Hill, and J.K. Barton, J. Phys. Chem. B. 107, 11805-11812 (2003). Abstract.
  • "Charge Transport in DNA" T.T. Williams and J.K. Barton, in DNA and RNA Binders: From Small Molecules to Drugs, Vol. 1, Eds. M. Demeunynck, C. Bailly, and W.D. Wilson, pp. 146-172, Wiley-VCH, Weinheim (2003).
  • "DNA-mediated Charge Transport for DNA Repair" E.M. Boon, A.L. Livingston, N.H. Chmiel, S.S. David, and J.K. Barton, Proc. Nat. Acad. Sci. 100, 12543-12547 (2003); 101, 4718-4718 (2004). Abstract.
  • "Electrochemical DNA Sensors" T.G. Drummond, M.G. Hill, and J.K. Barton, Nature Biotechnology 21, 1192-1199 (2003). Abstract. | Reprint in PDF format.
  • "Long-Range DNA Charge Transport" S. Delaney and J.K. Barton, J. Org. Chem. 68, 6475-6483 (2003). Abstract.
  • "Fast Back Electron Transfer Prevents Guanine Damage by Photoexcited Thionine Bound to DNA" C. Dohno, E.D.A. Stemp, and J.K. Barton, J. Am. Chem. Soc. 125, 9586-9587 (2003). Abstract.
  • "Rapid Radical Formation by DNA Charge Transport through Sequences Lacking Intervening Guanines" J. Yoo, S. Delaney, E.D.A. Stemp, and J.K. Barton, J. Am. Chem. Soc. 125, 6640-6641 (2003). Abstract.
  • "A Rhodium(III) Complex for High Affinity DNA Base Pair Mismatch Recognition" H. Junicke, J.R. Hart, J. Kisko, O. Glebov, I.R. Kirsch, and J.K. Barton, Proc. Nat. Acad Sci. USA 100, 3737-3742 (2003). Abstract.
  • 2002

  • "Effects of Strand and Directional Asymmetry on Base-Base Coupling and Charge Transfer in Double Helical DNA" M.A. O'Neill and J.K. Barton, Proc. Nat. Acad Sci. USA 99, 16543-16550 (2002). Abstract.
  • "1H-NMR Determination of Base Pair Lifetimes in Oligonucleotides Containing Single Base Mismatches" P.K. Bhattacharya, J. Cha, and J.K. Barton, Nucl. Acids. Res. 30, 4740-4750 (2002). Abstract.
  • "2-Aminopurine: A Probe of Structural Dynamics and Charge Transfer in DNA and DNA:RNA Hybrids" M.A. O'Neill and J.K. Barton, J. Am. Chem. Soc. 124, 13053-13066 (2002). Abstract.
  • "DNA Crosslinking with Metallointercalator-Peptide Conjugates" K.D. Copeland, A.M.K. Lueras, E.D.A. Stemp, and J.K. Barton, Biochemistry 41, 12785-12797 (2002). Abstract.
  • "An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3'-endo-Locked Sugar" E.M. Boon, J.K. Barton, P.I. Pradeepkumar, J. Isaksson, C. Petit, and J. Chattopadhyaya, Angew. Chem. Int. Ed. 41, 3402-3405 (2002).
  • "DNA-Mediated Charge Transport as a Probe of MutY/DNA Interaction" E.M. Boon, M.A. Pope, S.D. Williams, S.S. David, and J.K. Barton, Biochemistry 41, 8464-8470 (2002). Abstract.
  • "Charge Transport Through a Molecular p-Stack: Double Helical DNA" C.R. Treadway, M.G. Hill, and J.K. Barton, Chem. Phys. 281, 409-428 (2002). Abstract.
  • "DNA Mediated Charge Transport: Characterization of a DNA Radical Localized at an Artifical Nucleic Acid Base" M. Pascaly, J. Yoo, and J.K. Barton, J. Am. Chem. Soc. 124, 9083-9092 (2002). Abstract.
  • "Charge Transport in DNA" E.M. Boon and J.K. Barton, Curr. Opin. Struct. Biol. 12, 320-329 (2002). Abstract.
  • "Detection of DNA Base Mismatches Using DNA Intercalators" E.M. Boon, J.L. Kisko, and J.K. Barton, Methods in Enzymology 353, 506-522 (2002).
  • "Oxidative Charge Transport through DNA in Nucleosome Particles" M. E. Nunez, K. T. Noyes, and J. K. Barton, Chemistry & Biology, 9(4), 403-415, (2002). Abstract.
  • "Oxidative Damage by Ruthenium Complexes Containing the Dipyridophenazine Ligand or Its Derivatives: A Focus on Intercalation" S. Delaney, M. Pascaly, P.K. Bhattacharya, K. Han, and J.K. Barton, Inorg. Chem. 41, 1966-1974 (2002). Abstract.
  • "An Electrical Probe of Protein-DNA Interactions on DNA-Modified Surfaces" E. M. Boon, J. W. Salas, and J. K. Barton, Nature Biotechnology20, 282-286 (2002). Abstract.
  • "The Effect of Varied Ion Distributions on Long-Range Charge Transport in DNA" T.T. Williams and J.K. Barton, J. Am. Chem. Soc. 124, 1840-1841, (2002). Abstract.
  • "DNA Hydrolysis and Oxidative Cleavage by Metal-Binding Peptides Tethered to Rhodium Intercalators" K.D. Copeland, M.P. Fitzsimons, R.P. Houser, and J.K. Barton, Biochemistry 41, 343-356, (2002). Abstract.
  • 2001

  • "Evidence for DNA Charge Transport in the Nucleus" M.E. Núñez, G.P. Holmquist, and J.K. Barton, Biochemistry 40, 12465-12471 (2001). Abstract.
  • "Long Range Oxidative Damage in DNA/RNA Duplexes" D.T. Odom and J.K. Barton, Biochemistry, 40, 8727-8737 (2001). Abstract.
  • "Synthesis and Spectroelectrochemistry of Ir(bpy)(phen)(phi)3+, a Tris(heteroleptic) Metallointercalator" C. Stinner, M. D. Wightman, S. O. Kelley, M. G. Hill, J. K. Barton, Inorg. Chem., 40, 5245-5250 (2001).  Abstract.
  • "Morphology of 15-mer Duplexes Tethered to Au(111) using Scanning Probe Microscopy" M. Sam, E. M. Boon, J. K. Barton, M. G. Hill, and E. M. Spain, Langmuir, 17, 5727-5730 (2001).  Abstract.
  • "The Influence of Intervening Mismatches on Long-range Guanine Oxidation in DNA Duplexes" P. K. Bhattacharya and J. K. Barton, J. Am. Chem. Soc., 123, 8649-8656 (2001).  Abstract.
  • "How Different DNA-Binding Proteins Affect Long-Range Oxidative Damage to DNA" S.R. Rajski and J.K. Barton, Biochemistry, 40, 5556-5564 (2001). Abstract.
  • "Direct Observation of Radical Intermediates in Protein-dependent DNA Charge Transport" H.-A. Wagenknecht, S. R. Rajski, M. Pascaly, E. D. A. Stemp, and J. K. Barton, J. Am. Chem. Soc., 123, 4400-4407 (2001). Abstract.
  • "Charge Transport Through DNA Four-Way Junctions" D. T. Odom, E. A. Dill, and J. K. Barton, Nucleic Acids Research, 29, 2026-2033, (2001). Abstract.
  • "Bio-inorganic Chemistry: New Advances, New Directions and New Investigators" Ed. J. K. Barton and K. D. Karlin, Current Opinion in Chemical Biology, 5, 165 (2001).
  • 2000

  • "Luminescence Quenching by DNA-Bound Viologens: Effect of Reactant Identity on Efficiency and Dynamics of Electron Transfer in DNA" S. O. Kelley, G. Orellana, and J. K. Barton, Journal of Photochemistry and Photobiology B: Biology, 58, 72 (2000).
  • "Femtosecond Direct Observation of Charge Transfer between Bases in DNA" C. Wan, T. Fiebig, O. Schiemann, J. K. Barton, and A. H. Zewail, Proc. Nat. Acad Sci. USA, 97, 14052 (2000). Abstract.
  • "Probing Nucleic Acid Structure with Shape-Selective Rhodium and Ruthenium Complexes" B. A. Jackson and J. K. Barton, Current Protocols in Nucleic Acid Chemistry, 6.2.1-6.2.39, John Wiley & Sons, Inc. NY, (2000).
  • "Recognition of DNA Base Pair Mismatches by a Cyclometalated Rh(III) Intercalator"J.L. Kisko and J.K. Barton, Inorg. Chem. 39, 4942 -4949, (2000). Abstract.
  • "Mutation Detection by Electrocatalysis at DNA-Modified Electrodes"E.M. Boon, D.M. Ceres, T.G. Drummond, M.G. Hill, and J.K. Barton, Nature Biotechnology 18, 1096-1100, (2000). Abstract.
  • "Oxidative Repair of a Thymine Dimer in DNA from a Distance by a Covalently Linked Organic Intercalator"D.A. Vicic, D.T. Odom, M.E. Núñez, D.A. Gianolio, L.W. McLaughlin, and J.K. Barton, J. Am. Chem. Soc. 122, 8603-8611, (2000). Abstract.
  • "Variations in DNA Charge Transport with Nucleotide Composition and Sequence"T.T. Williams, D.T. Odom, and J.K. Barton, J. Am. Chem. Soc. 122, 9048-9049, (2000). Abstract.
  • "The Flash-Quench Technique in Protein-DNA Electron Transfer: Reduction of Guanine Radical by Ferrocytochrome c"E.D.A. Stemp and J.K. Barton, Inorg. Chem 39, 3868-3874 (2000). Abstract.
  • "EPR Detection of Guanine Radicals in a DNA Duplex under Biological Conditions: Selective Base Oxidation by Ru(phen)2dppz3+ using the Flash-Quench Technique"O. Schiemann, N.J. Turro, and J.K. Barton, J. Phys. Chem. B 104, 7214-7220 (2000). Abstract.
  • "Robust Charge Transport in DNA Double Crossover Assemblies" D.T. Odom, E.A. Dill, J.K. Barton, Chemistry and Biology 7, 475-481, (2000). Abstract.
  • "Damage to DNA by Long-Range Charge Transport" Nunez, M. E.; Rajski, S. R.; Barton, J. K. Methods in Enzymology 319, 165-188, (2000).
  • "Long-Range Guanine Oxidation in DNA Restriction Fragments by a Triplex-Directed Naphthalene Diimide Intercalator" M.E. Núñez, K.T. Noyes, D.A. Gianolio, L.W. McLaughlin, and J.K. Barton, Biochemistry 39, 6190-6199, (2000). Abstract.
  • "Recognition of Base Mismatches in DNA by 5,6-Chrysenequinone Diimine Complexes of Rhodium(III): A Proposed Mechanism for Preferential Binding in Destabilized Regions of the Double Helix"B.A. Jackson and J.K. Barton, Biochemistry 39, 6176-6182, (2000). Abstract.
  • "Probing DNA Charge Transport with Metallointercalators" M.E. Núñez and J.K. Barton, Current Opinion in Chemical Biology 4, 199-206 (2000). Abstract.
  • "DNA-Mediated Electron Transfer: A Sensitive Probe of DNA-Protein Interactions" S.R. Rajski and J.K. Barton, J. Biomol. Struct. Dynamics 11, 285-295, (2000). Abstract.
  • "DNA-bound Peptide Radicals generated through DNA-mediated Electron Transport" H.-A. Wagenknecht, E.D.A. Stemp, and J.K. Barton, Biochemistry 18, 5483-5491, (2000). Abstract.
  • "DNA Repair: Models for Damage and Mismatch Recognition" S.R. Rajski, B.A. Jackson, and J.K. Barton, Mutation Research 447, 49-72 (2000). Abstract.
  • "Structure of a Photoactive Rhodium Complex Intercalated into DNA" C.L. Kielkopf, K.E. Erkkila, B.P. Hudson, J.K. Barton, and D.C. Rees, Nature Structural Biology 7, 117-121, (2000). Abstract.
  • "Electron Transfer between Metal Complexes Bound to DNA: Variations in Sequence, Donor, and Metal Binding Mode" E.D.A. Stemp, R. E. Holmlin, and J.K. Barton, Inorg. Chim. Acta 297, 88-97, (2000). Abstract.
  • "Evidence of Electron Transfer from Peptides to DNA: Oxidation of DNA-bound Tryptophan using the Flash-quench Technique" H.-A. Wagenknecht, E.D.A. Stemp, and J.K. Barton, J. Am. Chem. Soc.122, 1-7, (2000). Abstract.
  • 1999

  • "The DNA Double Helix: A Medium for Long Range Charge Transport" J. K. Barton, McGraw-Hill 1999 Yearbook of Science & Technology, p.124.
  • "Spectral and Structural Characterization of 5,6-Chrysenequinone Diimine Complexes of Rhodium(III): Evidence for a pH Dependent Ligand Conformational Switch" B.A. Jackson, L.M. Henling, and J. K. Barton, Inorg. Chem.38, 6218 (1999).
  • "Single-Base Mismatch Detection Based on Charge Transduction Through DNA" S.O. Kelley, E.M. Boon, J.K. Barton, N.M. Jackson, and M.G. Hill, Nucleic Acids Research, 27, 4830-4837, (1999). Abstract.
  • "Synthesis of Metallointercalator-DNA Conjugates on a Solid Support" R.E. Holmlin, P.J. Dandliker, and J.K. Barton, Bioconjugate Chem. 10, 1122 (1999). Abstract.
  • " Recognition and Reaction of Metallointercalators with DNA" K.E. Erkkila, D.T. Odom and J.K. Barton, Chem. Rev., 99, 2777 (1999).
  • "Perturbing the DNA Sequence Selectivity of Metallointercalator-Peptide Conjugates by Single Amino Acid Modification" C. A. Hastings and J. K. Barton, Biochemistry, 38, 10042 (1999). Abstract.
  • "Protein-Modulated DNA Electron Transfer" S. R. Rajski, S. Kumar, R. J. Roberts, and J. K. Barton, J. Am. Chem. Soc., 121, 5615 (1999). Abstract.
  • "Femtosecond Dynamics of DNA-Mediated Electron Transfer" C. Wan, T. Fiebig, S. O. Kelley, C. R. Treadway, J. K. Barton, and A. H. Zewail, Proc. Nat. Acad Sci. USA, 96, 6014-6019 (1999). Abstract.
  • "A Versatile Mismatch Recognition Agent: Specific Cleavage of a Plasmid DNA at a Single Base Mispair", Brian A. Jackson, Viktor Y. Alekseyev, and Jacqueline K. Barton, Biochemistry, 38, 4655-4662 (1999). Abstract.
  • "Site-Specific Inhibition of Transcription Factor Binding to DNA by a Metallointercalator" D. T. Odom, C. S. Parker, and J. K. Barton, Biochemistry, 38, 5155 (1999). Abstract.
  • "Long Range Electron Transfer Through DNA Films" S. O. Kelley, N. M. Jackson, M. G. Hill and J. K. Barton, Angew. Chem. Int. Ed. Eng. 38(7), 941 (1999). Abstract.
  • "Metal-Dependent Intramolecular Chiral Induction: The Zn2+ Complex of an Ethidium-Peptide Conjugate" R. P. Houser, M. P. Fitzsimons and J. K. Barton, Inorg. Chem., 38, 1368 (1999). Abstract.
  • "Femtosecond Dynamics of the DNA Intercalator, Ethidium, and Electron Transfer with Mononucleotides in Water" T. Fiebig, C. Wan, S. O. Kelley, J. K. Barton, and A. H. Zewail, Proc. Natl. Acad. Sci. USA, 96, 1187 (1999). Abstract.
  • "Long Range Oxidative Damage to DNA: Effects of Distance and Sequence" M. E. Nunez, D. B. Hall and J. K. Barton, Chemistry and Biology, 6, 85 (1999). Abstract.
  • "Dipyridophenazine Complexes of Os(II) and Red-Emitting DNA Probes: Synthesis, Characterization, and Photophysical Properties" R. E. Holmlin, J. A. Yao and J. K. Barton, Inorg. Chem., 38, 174 (1999). Abstract.
  • "Electron Transfer Between Bases in Double Helical DNA" S. O. Kelley and J. K. Barton, Science, 283, 375 (1999). Abstract.
  • 1998

  • "Radical Migration Through the DNA Helix: Chemistry at a Distance" S. O. Kelley and J. K. Barton, Metal Ions in Biological Systems, 26, 211 (1998).
  • "Functionalized Rhodium Intercalators for DNA Recognition" R. H. Terbrueggen, T. W. Johann and J. K. Barton, Inorg. Chem., 37, 6874 (1998). Abstract.
  • "Orienting DNA Helices on Gold Using Applied Electric Fields" S. O. Kelley, J. K. Barton, N. M. Jackson, L. D. McPherson, A. B. Potter, E. M. Spain, M. J. Allen, and M. G Hill, Langmuir, 14, 6781 (1998).
  • "Differential DNA Recognition by the Enantiomers of 1-Rh(MGP)2phi: A Combination of Shape Selection and Direct Readout" S.J. Franklin and J. K. Barton, Biochemistry, 37, 16093 (1998). Abstract.
  • "Long-Range and Short-Range Oxidative Damage to DNA: Photoinduced Damage to Guanines in Ethidium-DNA Assemblies"D. B. Hall, S. O. Kelley, and J. K. Barton, Biochemistry, 37, 15933 (1998). Abstract.
  • "Long-Range Triplet Energy Transfer between Metallointercalators Tethered to DNA: Importance of Intercalation, Stacking and Distance" R. E. Holmlin, R. T. Tong, and J. K. Barton, J. Am. Chem. Soc. , 120, 9724 (1998). Abstract.
  • "A Reinvestigation of Circular Dichroism and NMR: Ru(II) and Rh(III) Metallointercalators Do Not Bind Cooperatively to DNA" S.J. Franklin, C. R. Treadway, and J. K. Barton, Inorg. Chem., 37, 5198 (1998). Abstract.
  • "DNA-Mediated Electron Transfer: Chemistry at a Distance" J. K. Barton, Pure and Applied Chemistry, 70, 873 (1998). Abstract.
  • "DNA-mediated Electron Transfer from a Modified Base to Ethidium: Pi-Stacking as a Modulator of Reactivity" S. O. Kelley and J. K. Barton, Chemistry and Biology, 5, 413 (1998). Abstract.
  • "Solution Structure of a Metallointercalator Bound Site-Specifically to DNA" B. P. Hudson and J. K. Barton, J. Am. Chem. Soc., 120, 6877 (1998). Abstract.
  • "Solution Photoreactivity of Phenanthrenequinone Diimine Complexes of Rhodium and Correlations with DNA Photocleavage and Photooxidation" C. Turro, D. B. Hall, W. Chen, H. Zuilhof, J. K. Barton, and N.J. Turro, J. Phys. Chem. A, 102, 5708 (1998). Abstract.
  • "Rh(phen)2phi3+ as a Shape-selective Probe of Triple Helices" A. C. Lim and J. K. Barton, Biochemistry, 37, 9138 (1998). Abstract.
  • "A Versatile Synthetic Approach to Rhodium(III) Diimine Metallointercalators: Condensation of ortho-Quinones with Coordinated cis-Ammines" H.R. Murner, B.A. Jackson, and J. K. Barton, Inorg. Chem., 37, 3007 (1998). Abstract.
  • "Paradigms, Supermolecules, Electron Transfer and Chemistry at a Distance. What's the Problem? The Science or the Paradigm?" N. J. Turro and J. K. Barton, J. Biol. Inorg. Chem, 3, 201 (1998).
  • "Oxidative Charge Transfer to Repair Thymine Dimers and Damage Guanine Bases in DNA assemblies Containing Tethered Metallointercalators" P. J. Dandliker, M. E. Nunez, and J. K. Barton, Biochemistry, 37, 6491 (1998). Abstract.
  • "Ru(phen)2(dppz)2+ Luminescence: Dependence on DNA Sequences and Groove Binding Agents" R. E. Holmlin, E. D. A. Stemp, and J. K. Barton, Inorg. Chem., 37, 29 (1998). Abstract.
  • 1997

  • "Recognition of DNA Base Mismatches by a Rhodium Intercalator" B. A. Jackson and J. K. Barton, J. Am. Chem. Soc., 119, 12986 (1997). Abstract.
  • "DNA Recognition by Metal-Peptide Complexes Containing the Recognition Helix of the Phage 434 Repressor" N. Y. Sardesai and J. K. Barton, J. Biol. Inorg. Chem., 2, 762 (1997). Abstract.
  • "Charge Transfer Through the DNA Base Stack" R. E. Holmlin, P. J. Dandliker, J. K. Barton, Angew. Chem. 109, 2830 (1997); Angew. Chem. Intl. Ed. Eng. 36, 2714 (1997). Abstract.
  • "First Observation of the Key Intermediate in the "Light-Switch" Mechanism of [Ru(phen)2(dppz)]2+" E. J. C. Olson, D. Hu, A. Hormann, A. M. Jonkman, M. R. Arkin, E. D. A. Stemp, J. K. Barton, and P. F. Barbara, J. Am. Chem. Soc., 119, 11458 (1997). Abstract.
  • "Photoinduced Electron Transfer in Ethidium-Modified DNA Duplexes: Dependence on Distance and Base Stacking" S. O. Kelley, R. E. Holmlin, E. D. A. Stemp and J. K. Barton, J. Am. Chem. Soc., 119, 9861 (1997). Abstract.
  • "Resonance Raman Investigation of Ru(phen)2(dppz)2+ and Related Complexes in Water and in the Presence of DNA" W. Chen, C. Turro, L. A. Friedman, J. K. Barton, and N. J. Turro, J. Phys. Chem. B, 101, 6995 (1997). Abstract.
  • "Targeting the Tat-Binding Site of Bovine Immunodeficiency Virus TAR RNA with a Shape-Selective Rhodium Complex" A.C. Lim and J.K. Barton, Bioorg. & Med. Chem., 5, 1131 (1997). Abstract.
  • "Long-Range Oxidation of Guanine by Ru(III) in Duplex DNA" M.R. Arkin, E.D.A. Stemp, S. Coates Pulver, and J.K. Barton, Chemistry and Biology, 4, 389 (1997). Abstract.
  • "Sensitivity of DNA-mediated Electron Transfer to the Intervening pi-Stack: A Probe for the Integrity of the DNA Base Stack" D.B. Hall and J.K. Barton, J. Am. Chem. Soc., 119, 5045 (1997). Abstract.
  • "Design of a Synthetic Nuclease: DNA Hydrolysis by a Zinc-binding Protein Tethered to a Rhodium Intercalator" M. P. Fitzsimons and J. K. Barton, J. Am. Chem. Soc., 119, 3379 (1997). Abstract.
  • "Oxidation of Guanine in DNA by Ru(phen)2dppz2+ Using the Flash-Quench Technique" E. D. A. Stemp, M. R. Arkin and J. K. Barton, J. Am. Chem. Soc., 119, 2921 (1997). Abstract.
  • "Oxidative Thymine Dimer Repair in the DNA Helix" P. J. Dandliker, R. E. Holmlin, and J. K. Barton, Science, 275, 1465 (1997). Abstract.
  • "Electrochemistry of Methylene Blue bound to a DNA-Modified Electrode" S. O. Kelley, J. K. Barton, N. Jackson, and M. G. Hill, Bioconjugate Chemistry, 8, 31 (1997). Abstract.
  • "Structural Studies of L- and D-[Ru(phen)2dppz]2+ Bound to d(GTCGAC)2: Characterization of Enantioselective Intercalation" C. M. Dupureur and J. K. Barton, Inorg. Chem., 36, 33 (1997). Abstract.
  • 1996

  • "Effect of Guest/Host Interactions on Photoinduced Electron Transfer Reactions" C. Turro, S. H. Bossmann, S. Niu, J. K. Barton, and N. J. Turro, Inorg. Chim. Acta, 252, 333 (1996).
  • "The Assembly of Transition Metal Complexes for Site-Specific Recognition of Nucleic Acids" C. M. Dupureur and J. K. Barton, in Comprehensive Supramolecular Chemistry, Vol. 5, Ed. J.-M. Lehn, Pergamon Press, 295-315 (1996).
  • "Oxidative DNA Damage through Long Range Electron Transfer" D. B. Hall, R. E. Holmlin, and J. K. Barton, Nature, 382, 731 (1996). Abstract.
  • "Rates of DNA-mediated Electron Transfer between Metallointercalators" M. R. Arkin, E. D. A. Stemp, R. E. Holmlin, J. K. Barton, A. Hoermann, E. J. C. Olson, and P. F. Barbara, Science, 273, 475 (1996). Abstract.
  • "Os(phen)2dppz2+ in Photoinduced DNA-mediated Electron Transfer Reactions" R. E. Holmlin, E. D. A. Stemp, and J. K. Barton, J. Am. Chem. Soc., 118, 5236 (1996). Abstract.
  • "Excited State Properties of Rh(phi)2(phen)3+ and Related Complexes: A Strong Photooxidant" C. Turro, A. Evenzahav, S. H. Bossmann, J. K. Barton, and N. J. Turro, Inorg. Chim. Acta, 243, 101 (1996).
  • "Electron Transfer between Metal Complexes Bound to DNA: Is DNA a Wire?"E. D. A. Stemp and J. K. Barton in Metal Ions in Biological Systems, Vol. 33, Ed. Helmut Sigel, 325-362 (1996).
  • "Luminescence Quenching in Supramolecular Systems: A Comparison of DNA- and SDS Micelle-Mediated Photoinduced Electron Transfer between Metal Complexes" M. R. Arkin, E. D. A. Stemp, C. Turro, N. J. Turro and J. K. , Barton, J. Am. Chem. Soc., 118, 2267 (1996). Abstract.
  • "Recognition of DNA by Octahedral Coordination Complexes" T. W. Johann and J. K. Barton, Phil. Trans. Royal Soc. (London), 354, 1706, 299 (1996).
  • 1995

  • "A Structural Examination of Enantioselective Intercalation: 1H NMR of Rh(en)2phi3+ Isomers Bound to d(GTGCAC)2" T. P. Shields and J. K. Barton, Biochemistry, 34, 15049 (1995). Abstract.
  • "Sequence-selective DNA Recognition and Photocleavage: A Comparison of Enantiomers of Rh(en)2phi3+" T. P. Shields and J. K. Barton, Biochemistry, 34, 15037 (1995). Abstract.
  • "1H NMR Structural Evidence for the Sequence-Specific Design of an Intercalator: D-a-[Rh[(R,R)-Me2trien]phi]3+ Bound to d(GAGTGCACTC)2" B. P. Hudson, C. M. Dupureur and J. K. Barton, J. Am. Chem. Soc., 117, 9379 (1995). Abstract.
  • "Construction of Coordinatively Saturated Rhodium Complexes Containing Appended Peptides" N. Y. Sardesai, S. C. Lin, K. Zimmermann, and J. K. Barton, Bioconjugate Chemistry, 6, 302 (1995). Abstract.
  • "Sequence-Specific DNA Binding by a Rhodium Complex: Recognition based on Sequence-Dependent Twistability" R. H. Terbrueggen and J. K. Barton, Biochemistry, 34, 8227 (1995). Abstract.
  • "Electron Transfer between Metallointercalators Bound to DNA: Spectral Identification of the Transient Intermediate" E. D. A. Stemp, M. R. Arkin, and J. K. Barton, J. Am. Chem. Soc., 117, 2375 (1995). Abstract.
  • "Os(phen)2dppz2+: A Red-emitting DNA Probe" R. E. Holmlin and J. K. Barton, Inorg. Chem., 34, 7 (1995). Abstract.
  • "Metallointercalators as Probes of the DNA pi-Way" M. R. Arkin, Y. Jenkins, C. J. Murphy, N. J. Turro and J. K. Barton, ACS Advances in Chemistry Series, 246, 449-469 (1995).
  • "Proton Transfer Quenching of the MLCT Excited State of Ru(phen)2dppz2+ in Homogeneous Solution and Bound to DNA" C. Turro, S. H. Bossmann, Y. Jenkins, J. K. Barton, and N. J. Turro, J. Am. Chem. Soc., 117, 9026 (1995).
  • "Recognition of Nucleic Acids by Transition Metal Complexes" A. Sitlani and J. K. Barton, in Handbook on Metal-Ligand Interactions in Biological Fluids, Bioinorganic Chemistry, Vol. 1, Part 2, Ed. G. Berthon, pp. 466-487, Marcel Dekker, Inc., New York (1995).
  • 1994

  • "Use of Selective Deuteration and 1H NMR in Demonstrating Major Groove Binding of D-[Ru(phen)2dppz]2+ to d(GTCGAC)2" C. M. Dupureur and J. K. Barton, J. Am. Chem. Soc., 116, 10286 (1994). Abstract.
  • "Sequence Specific Recognition of DNA by Phenanthrenequinone Diimine Complexes of Rhodium(III): Importance of Steric and van der Waals Interactions" A. Sitlani and J. K. Barton, Biochemistry, 33, 12100 (1994). Abstract.
  • "DNA Recognition by Peptide Complexes of Rhodium(III): Example of a Glutamate Switch" N. Y. Sardesai, K. Zimmermann, and J. K. Barton, J. Am. Chem. Soc., 116, 7502 (1994). Abstract.
  • "1H-NMR of Rh(NH3)4phi3+ Bound to d(TGGCCA)2: Classical Intercalation by a Non-classical Octahedral Metal Complex" J. G. Collins, T. P. Shields, and J. K. Barton, J. Am. Chem. Soc., 116, 9840 (1994). Abstract.
  • "Fast Photoinduced Electron Transfer through DNA Intercalation" C. J. Murphy, M. R. Arkin, N. D. Ghatlia, S. H. Bossmann, N. J. Turro, and J. K. Barton, Proc. Nat. Acad. Sci. USA, 91, 5315 (1994). Abstract.
  • "Rational Construction of Metallointercalators: Syntheses, Structures, and Characterization of Isomers of (2S,9S)-Diamino-4,7-diazadecane-9,10- phenanthrenequinone diimine Rhodium(III)" A. H. Krotz and J. K. Barton, Inorg. Chem., 33, 1940 (1994). Abstract.
  • "Correlations of Crystal Structures of DNA Oligonucleotides with Enantioselective Recognition by Rh(phen)2phi3+: Probes of DNA Propeller Twisting in Solution" D. Campisi, T. Morii, and J. K. Barton, Biochemistry, 33, 4130 (1994). Abstract.
  • "Ligand-Specific Charge-Localization in the MLCT Excited State of Ru(bpy)2DIP2+ Monitored by Time-Resolved Resonance Raman Spectroscopy" C. Turro, S. H. Bossmann, G. E. Leroi, J. K. Barton, and N. J. Turro, Inorg. Chem., 33, 1344 (1994).
  • "DNA Footprinting with Rh(phi)2bpy3+ " S. L. Klakamp and J. K. Barton, Methods in Molecular Biology, 31, 331 (1994).
  • "Metal/Nucleic Acid Interactions" J. K. Barton, in Bioinorganic Chemistry, University Press, 455 (1994).
  • 1993

  • "Assembly of DNA Recognition Elements on an Octahedral Rhodium Intercalator: Predictive Recognition of 5'-TGCA-3' by D-[Rh[(R,R)- Me2trien]phi]3+" A. H. Krotz, B. P. Hudson, and J. K. Barton, J. Am. Chem. Soc., 115, 12577 (1993). Abstract.
  • "Enantiospecific Palindromic Recognition of 5'-d(CTCTAGAG)-3' by a Novel Rhodium Intercalator: Analogies to a DNA-Binding Protein" A. Sitlani, C. M. Dupureur, and J. K. Barton, J. Am. Chem. Soc., 115, 12589 (1993). Abstract.
  • "Metallointercalators: Syntheses, Structures, and Photochemical Characterizations of Phenanthrenequinone Diimine Complexes of Rhodium (III)" A. H. Krotz, L. Y. Kuo, and J. K. Barton, Inorg. Chem., 32, 5963 (1993). Abstract.
  • "Long Range Photoinduced Electron Transfer through a DNA Helix" C. J. Murphy, M. R. Arkin, Y. Jenkins, N. D. Ghatlia, S. Bossmann, N. J. Turro and J. K. Barton, Science, 262, 1025 (1993). Abstract.
  • "Photoinduced Electron Transfer Through the Double Helix: Is DNA a Wire?" J. K. Barton, Proceedings of the Robert A. Welch Foundation 37th Conference on Chemical Research: 40 Years of the DNA Double Helix, Houston, Texas, Oct. 25-26, 1993.
  • "Chemical Probing of tDNAPhe with Transition Metal Complexes: A Structural Comparison of RNA and DNA" A. C. Lim and J. K. Barton, Biochemistry , 32, 11029 (1993). Abstract.
  • "A Distinct Intron-DNA Structure in Simian Virus 40 T-Antigen and Adenovirus 2 E1A Genes" I. Lee and J. K. Barton, Biochemistry, 32, 6121 (1993).
  • "How to Make a Molecular Light Switch Sequence-Specific: Tethering of an Oligonucleotide to a Dipyridophenazine Complex of Ruthenium(II)" Y. Jenkins and J. K. Barton, Proceedings of Advances in Fluorescence Sensing Technology, SPIE, 1885, 129 (1993).
  • "Ruthenium Complexes as Luminescent Reporters of DNA" C. J. Murphy and J. K. Barton, Methods in Enzymology, 226, 576 (1993).
  • "DNA Photofootprinting with Rh(phi)2bpy3+" S. L. Klakamp and J. K. Barton, Methods in Molecular Biology, 31, 331 (1993).
  • "DNA Recognition by Rhodium(III) Polyamine Intercalators: Considerations of Hydrogen Bonding and van der Waals Interactions" A. H. Krotz, L. Y. Kuo, T. P. Shields, and J. K. Barton, J. Am. Chem. Soc., 115, 3877 (1993). Abstract.
  • "NMR Evidence for Specific Intercalation of D-Rh(phen)2phi3+ in [d(GTCGAC)]2" S. S. David and J. K. Barton, J. Am. Chem. Soc., 115, 2984 (1993). Abstract.
  • 1992

  • "Metallointercalators: Structure of rac-Bis(ethylenediamine)(9,10- phenanthrenequinone diimine)rhodium(III) Tribromide Trihydrate" W. P. Schaefer, A. H. Krotz, L. Y. Kuo, T. P. Shields, and J. K. Barton, Acta Cryst., 48, 2071 (1992).
  • "Characterization of Dipyridophenazine Complexes of Ruthenium(II): The Light Switch Effect as a Function of Nucleic Acid Sequence and Conformation" Y. Jenkins, A. E. Friedman, N. J. Turro, and J. K. Barton, Biochemistry, 31, 10809 (1992).
  • "Nitroxide Labeled Ru(II)-Polypyridyl Complexes as EPR Probes to Study Organized Systems: 2. Combined Photophysical and EPR Investigations of B-DNA" M. F. Ottaviani, N. D. Ghatlia, S. H. Bossmann, J. K. Barton, H. Durr, and N. J. Turro, J. Am. Chem. Soc., 114, 8946 (1992).
  • "A Sequence-Specific Molecular Light Switch: Tethering of an Oligonucleotide to a Dipyridophenazine Complex of Ruthenium(II)" Y. Jenkins and J. K. Barton, J. Am. Chem. Soc., 114, 8736 (1992).
  • "Transition Metal Complexes as Probes of Nucleic Acids" C. S. Chow and J. K. Barton, in Methods in Enzymology, 212, 219-242 (1992).
  • "Novel Dipyridophenazine Complexes of Ruthenium(II): Exploring Luminescent Reporters of DNA" R. M. Hartshorn and J. K. Barton, J. Am. Chem. Soc., 114, 5919 (1992).
  • "Recognition of G-U Mismatches by Tris(4,7-Diphenyl-1,10-phenanthroline) Rhodium(III)" C. S. Chow and J. K. Barton, Biochemistry, 31, 5423 (1992).
  • "Protein Surface Recognition and Covalent Binding by Chromium Nitrilotriacetate Complexes: Elucidation using NMR and CD Spectroscopy" J. R. Bocarsly and J. K. Barton, Inorg. Chem., 31, 2827 (1992).
  • "Delineation of Structural Domains in Eukaryotic 5S rRNA with a Rhodium Probe" C. S. Chow, K. M. Hartmann, S. L. Rawlins, P. W. Huber, and J. K. Barton, Biochemistry, 31, 3534 (1992).
  • "Recognition of Tertiary Structure in tRNAs by Rh(phen)2phi3+: A New Reagent for RNA Structure-Function Mapping" C. S. Chow, L. S. Behlen, O. C. Uhlenbeck, and J. K. Barton, Biochemistry, 31, 972 (1992).
  • "DNA Photocleavage by Phenanthrenequinone Diimine Complexes of Rhodium(III): Shape-Selective Recognition and Reaction" A. Sitlani, E. C. Long, A. M. Pyle, and J. K. Barton, J. Am. Chem. Soc., 114, 2303 (1992).
  • "Imaging of Oligonucleotide-Metal Complexes by Scanning Tunneling Microscopy" Y. Kim, E. C. Long, J. K. Barton, and C. M. Lieber, Langmuir, 8, 496 (1992).
  • 1991

  • "Photoinduced Electron Transfer Quenching of Excited Ru(II) Polypyridyls Bound to DNA: The Role of the Nucleic Acid Double Helix" G. Orellana, A. K.- D. Mesmaeker, J. K. Barton, and N. J. Turro, Photochemistry and Photobiology, 54, 499 (1991).
  • "Structural Polymorphism in the Major Groove of a 5S RNA Gene Complements the Zinc Finger Domains of Transcription Factor IIIA" P. W. Huber, T. Morii, H.-Y. Mei, and J. K. Barton, Proc. Nat. Acad. Sci. USA, 88, 10801 (1991).
  • "Molecular Recognition and Chemistry in Restricted Reaction Spaces. Photophysics and Photoinduced Electron Transfer on the Surfaces of Micelles, Dendrimers and DNA" N. J. Turro, J. K. Barton, and D. A. Tomalia, Acc. Chem. Res., 24, 332 (1991).
  • "Photoelectron Transfer Between Molecules Adsorbed in Restricted Spaces" N. J. Turro, J. K. Barton, and D. Tomalia in Photochemical Conversion and Storage of Solar Energy, 121-139, E. Pelizzetti and M. Schiavello (Eds.), Kluwer Academic Publishers, the Netherlands (1991).
  • "Luminescence of Ruthenium(II) Polypyridyls: Evidence for Intercalative Binding to Z-DNA" A. E. Friedman, C. V. Kumar, N. J. Turro, and J. K. Barton, Nucleic Acids Research, 19, 2595 (1991).
  • 1990

  • "Molecular 'Light Switch' for DNA: Ru(bpy)2(dppz)2+" A. E. Friedman, J.-C. Chambron, J.-P. Sauvage, N. J. Turro, and J. K. Barton, J. Am. Chem. Soc., 112, 4960 (1990).
  • "Synthesis, Characterization, and Solution Chemistry of a Family of Protein Binding Inorganic Complexes: Bis(imidazole)(amino-acid-N,N- diacetato)Chromium(III)" J. R. Bocarsly, M. Y. Chiang, L. Bryant, and J. K. Barton, Inorg. Chem., 29, 4898 (1990).
  • "On Demonstrating DNA Intercalation" E. C. Long and J. K. Barton, Acc. Chem. Res., 23, 271 (1990).
  • "Synthesis and Characterization of Physical, Electronic, and Photochemical Aspects of 9,10-Phenanthrenequinone Diimine Complexes of Ruthenium(II) and Rhodium(III)" A. M. Pyle, M. Chiang, and J. K. Barton, Inorg. Chem., 29, 4487 (1990).
  • "Ligand-Dependent Interaction of Ruthenium(II) Polypyridyl Complexes with DNA Probed by Emission Spectroscopy" A. Kirsch-De Mesmaeker, G. Orellana, J. K. Barton, and N. J. Turro, Photochemistry & Photobiology, 52, 3, 461 (1990).
  • "Probing Microstructures in Double Helical DNA with Chiral Metal Complexes: Recognition of Changes in Base-Pair Propeller Twisting in Solution" A. M. Pyle, T. Morii, and J. K. Barton, J. Am. Chem. Soc., 112, 9432 (1990).
  • "Shape-selective Cleavage of tRNAPhe by Transition Metal Complexes" C. S. Chow and J. K. Barton, J. Am. Chem. Soc., 112, 2839 (1990).
  • 1989

  • "High Resolution Footprinting of EcoRI and Distamycin with Rh(phi)2bpy3+, a New Photofootprinting Reagent" K. Uchida, A. M. Pyle, T. Morii, and J. K. Barton, Nucleic Acids Research, 17, 10259 (1989).
  • "Probing Nucleic Acids with Transition Metal Complexes" A. M. Pyle and J. K. Barton, Progress in Inorganic Chemistry: Bioinorganic Chemistry, Vol. 38, Ed. S. J. Lippard, 413-475, John Wiley & Sons, Inc. (1990).
  • "Towards the Design of Synthetic Restriction Enzymes with Transition Metal Complexes" J. K. Barton, in Frontiers of Chemistry: Biotechnology, Chem. Abstracts Service, Columbus, OH, 5-25 (1989).
  • "1H NMR Studies of Tris(phenanthroline) Metal Complexes Bound to Oligonucleotides: Structural Characterizations via Selective Paramagnetic Relaxation" J. P. Rehmann and J. K. Barton, Biochemistry, 29, 1710 (1990).
  • "1H NMR Studies of Tris(phenanthroline) Metal Complexes Bound to Oligonucleotides: Characterization of Binding Modes" J. P. Rehmann and J. K. Barton, Biochemistry, 29, 1701 (1990).
  • "Shape-selective Targeting of DNA by Phenanthrenequinone diimine Rhodium(III) Photocleaving Agents" A. M. Pyle, E. C. Long, and J. K. Barton, J. Am. Chem. Soc., 111, 4520 (1989).
  • "Protein Site Recognition by Chromium(III) Complexes Probed through NOE Quenching" J. R. Bocarsly and J. K. Barton, Inorg. Chem., 28, 4189 (1989).
  • "Mixed Ligand Complexes of Ruthenium(II): Factors Governing Binding to DNA" A. M. Pyle, J. P. Rehmann, R. Meshoyrer, C. V. Kumar, N. J. Turro, and J. K. Barton, J. Am. Chem. Soc., 111, 3051 (1989).
  • "Excited State Resonance Raman Spectroscopy as a Probe of Alumina-Sodium Dodecyl Sulfate Hemimicelles" P. Somasundaran, J. T. Kunjappu, C. V. Kumar, N. J. Turro, and J. K. Barton, Langmuir, 5, 215 (1989).
  • 1988

  • "Rh(DIP)33+: A Shape-Selective Metal Complex which Targets Cruciforms" M. R. Kirshenbaum, R. Tribolet, and J. K. Barton, Nucleic Acids Research, 16, 7948 (1988).
  • "Biotechnology and Materials Science" Ed. M. Good, Assoc. Ed. J. K. Barton, American Chemical Society, Washington, DC (1988).
  • "Recognizing DNA Structures" J. K. Barton, Chemical and Engineering News, 66, 30-42 (1988).
  • "Metallonucleases: Real and Artificial" L. A. Basile and J. K. Barton, Metal Ions in Biological Systems, 25, 31 (1989).
  • "Accelerated Electron Transfer between Metal Complexes Mediated by DNA" M. D. Purugganan, C. V. Kumar, N. J. Turro, and J. K. Barton, Science, 241, 1645 (1988).
  • "Metal Complexes which Target DNA Sites: Coupling Recognition to Reactivity" M. B. Fleisher, H. Y. Mei and J. K. Barton, Nucleic Acids and Molecular Biology, 2, 65 (1988).
  • "Tris(tetramethylphenanthroline)Ruthenium(II): A Chiral Probes that Cleaves A-DNA Conformations" H. Y. Mei and J. K. Barton, Proc. Nat. Acad. Sci. USA, 85, 1339 (1988).
  • "Spectroscopic Investigations of the Interactions Between Polypyridyl Ruthenium Complexes and Anionic Polyelectrolytes" G. L. Duveneck, C. V. Kumar, N. J. Turro, and J. K. Barton, J. Phys. Chem., 92, 2028 (1988).
  • "In Vivo Photoreaction of a Chiral Cobalt Complex: DNA Cleavage by L-Co(DIP)33+ in Mammalian Cells" L. B. Chapnick, L. A. Chasin, A. L. Raphael, and J. K. Barton, Mutation Research, 201, 17 (1988).
  • "Energy Redistribution and Localization in the Excited States of Ruthenium(II) Polypyridyl Complexes" C. V. Kumar, J. K. Barton, I. R. Gould, N. J. Turro, and J. Van Hooten, Inorg. Chem., 27, 648 (1988).
  • 1987

  • "Factors Influencing the Excited State Behavior of Ruthenium Complexes Absorbed on Aqueous Laponite" N. J. Turro, C. V. Kumar, Z. Gruver, and J. K. Barton, Langmuir, 3, 1056 (1987).
  • "Metal-Activated Hydrolytic Cleavage of DNA" L. A. Basile, A. L. Raphael, and J. K. Barton, J. Am. Chem. Soc., 109, 7550 (1987).
  • "Design of a Double-Stranded DNA Cleaving Agent with Two Polyamine Metal-Binding Arms: Ru(DIP)2Macron+" L. A. Basile and J. K. Barton, J. Am. Chem. Soc., 109, 7548 (1987).
  • "Synthesis and Spectroscopic Characterization of the Purple Tris(phenanthrenequinonediimine)Ruthenium(II)" A. M. Pyle and J. K. Barton, Inorg. Chem., 26, 3820 (1987).
  • "Time Resolved Resonance Raman Spectra of Polypyridyl Complexes of Ruthenium(II)" C. V. Kumar, J. K. Barton, N. J. Turro, and I. R. Gould, Inorg. Chem., 26, 1455 (1987).
  • "Evidence of Altered DNA Conformations in the SV40 Genome: Site-Specific DNA Cleavage by the Chiral Complex L-Co(DIP)33+" B. C. Muller, A. L. Raphael, and J. K. Barton, Proc. Nat. Acad. Sci. USA, 84, 1764 (1987).
  • 1986

  • "A Chiral Probe for A-form Helices of DNA and RNA: Tris(tetramethylphenanthroline)ruthenium(II)" H. Y. Mei and J. K. Barton, J. Am. Chem. Soc., 108, 7414 (1986).
  • "Light Induced Cleavage of DNA by Metal Complexes" M. B. Fleisher, K. C. Waterman, N. J. Turro, and J. K. Barton, Inorg. Chem., 25, 3549 (1986).
  • "DNA Mediated Photoelectron Transfer Reactions" J. K. Barton, C. V. Kumar, and N. J. Turro, J. Am. Chem. Soc., 108, 6391 (1986).
  • "Metals and DNA: Molecular Left-Handed Complements" J. K. Barton, Science, 233, 727 (1986).
  • "Binding Modes and Base Specificity of Tris(phenanthroline)Ruthenium(II) Enantiomers with Nucleic Acids Tuning the Stereoselectivity" J. K. Barton, J. M. Goldberg, C. V. Kumar, and N. J. Turro, J. Am. Chem. Soc., 108, 2081 (1986).
  • "Probing Nucleic Acid Structure with Metallointercalators" C. V. Kumar, A. L. Raphael, and J. K. Barton, Biomolecular Stereodynamics, 3, 85 (1986).
  • "Crystal and Molecular Structure of a Chiral-Specific DNA-Binding Agent: Tris(4,7-diphenylphenanthroline)Ruthenium(II)" B. M. Goldstein, J. K. Barton, and H. M. Berman, Inorg. Chem., 25, 842 (1986).
  • "The Restriction Endonuclease EcoRI Alters the Enantiomeric Preferences of Chiral Metallointercalators for DNA: An Illustration of a Protein-Induced DNA Conformational Change" J. K. Barton and S. R. Paranawithana, Biochemistry, 25, 2205 (1986).
  • 1985

  • "Photophysics of Ruthenium Complexes Bound to Double Helical DNA" C. V. Kumar, J. K. Barton, and N. J. Turro, J. Am. Chem. Soc., 107, 5518 (1985).
  • "Site-Specific Cleavage of Left-handed DNA in pBR322 by L-Co(DIP)33+" J. K. Barton and A. L. Raphael, Proc. Nat. Acad. Sci. USA , 82, 6460 (1985).
  • "Chiral Discrimination in the Covalent Binding of Bis(phenanthroline) dichlororuthenium(II) to B-DNA" J. K. Barton and E. Lolis, J. Am. Chem. Soc., 107, 708 (1985).
  • "Simple Coordination Complexes: Drugs and Probes for DNA Structure" J. K. Barton, Comm. Inorg. Chem., 3, 321 (1985).
  • 1984

  • "Application of Chiral Lanthanide-induced Shift Reagents to Optically Active Cations: The Use of Tris[-trifluoromethylhydroxymethylene)-D-camphorato]europium(III) to Determine the Enantiomeric Purity of Tris(phenanthroline)Ruthenium(II) Dichloride" J. K. Barton and J. S. Nowick, J. Chem. Soc., Chem. Comm., 1650 (1984).
  • "Photoactivated Stereospecific Cleavage of Double-Helical DNA by Cobalt(III) Complexes" J. K. Barton and A. L. Raphael, J. Am. Chem. Soc., 106, 2466 (1984).
  • "Chiral Probes for the Handedness of DNA Helices: Enantiomers of tris(4,7- diphenylphenanthroline)ruthenium(II)" J. K. Barton, L. A. Basile, A. Danishefsky, and A. Alexandrescu, Proc. Nat. Acad. Sci. USA, 81, 1961 (1984).
  • "Tris(phenanthroline)ruthenium(II): Stereoselectivity in Binding to DNA" J. K. Barton, A. T. Danishefsky, and J. M. Goldberg, J. Am. Chem. Soc., 106, 2172 (1984).
  • 1983

  • "Tris(phenanthroline) Metal Complexes: Probes for DNA Helicity" J. K. Barton, Journal of Biomolecular Structure and Dynamics, 1, 621 (1983).
  • "A Cobalt Derivative of the Restriction Enzyme EcoRI" J. K. Barton and L. A. Basile, Inorg. Chim. Acta, 79, 152 (1983).
  • "Trifluoroacetolysis of Optically Active 2-Butyl Tosylate" J. J. Dannenberg, J. K. Barton, B. Bunch, B. J. Goldberg, and T. Kowalski, J. Org. Chem., 48, 4524 (1983).
  • "Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism" M. Tomasz, J. K. Barton, C. C. Magliozzo, D. Tucker, E. M. Lafer, and B. D. Stollar, Proc. Nat. Acad. Sci. USA, 80, 2874 (1983).
  • 1982

  • "Enantiomeric Selectivity in Binding Tris(phenanthroline)zinc(II) to DNA" J. K. Barton, J. J. Dannenberg, and A. L. Raphael, J. Am. Chem. Soc., 104, 4967 (1982).
  • "The Presence of Zinc in the Restriction Enzyme EcoRI" J. K. Barton, L. A. Basile, and S. Paranawithana, J. Biol. Chem., 257, 7911 (1982).
  • "13C Nuclear Magnetic Resonance Study of Trehalose Mobilization in Yeast Spores" J. K. Barton, J. A. den Hollander, J. J. Hopfield, and R. G. Shulman, Journal of Bacteriology, 151, 177 (1982).
  • 1981

  • "The 2-Butyl Cation in Trifluoroacetic Acid. A Hydrogen-Bridged Carbonium Ion" J. J. Dannenberg, B. F. Goldberg, J. K. Barton, K. Dill, D. H. Weinwurzel, and M. O. Longas, J. Am. Chem. Soc., 103, 7764 (1981).
  • 1980

  • "Measurement of the Internal pH of Yeast Spores by 31P Nuclear Magnetic Resonance" J. K. Barton, J. A. den Hollander, T. M. Lee, A. MacLaughlin, and R. G. Shulman, Proc. Nat. Acad. Sci. USA, 77, 2470 (1980).
  • "Heavy Metal Interactions with Nucleic Acids" J. K. Barton and S. J. Lippard, Metal Ions In Biology, ed. T. G. Spiro, 1, 31 (1980).
  • 1979

  • "Binding of cis- and trans-Dichlorodiammineplatinum(II) to DNA. Evidence of Unwinding and Shortening of the Double Helix" G. L. Cohen, W. R. Bauer, J. K. Barton, and S. J. Lippard, Science, 203, 1014 (1979).
  • "Chemical and Spectroscopic Characterization of cis-Diammineplatinum a-Pyridone Blue in Aqueous Solution. Comparison with Other Platinum Blues" J. K. Barton, C. Caravana, and S. J. Lippard, J. Am. Chem. Soc., 101, 7269 (1979).
  • "Cooperative Binding of a Platinum Metallointercalation Reagent of Poly(A)-Poly(U)" J. K. Barton and S. J. Lippard, Biochemistry, 18 (12), 2661 (1979).
  • "Solid State Structure, Magnetic Susceptibility, and Single Crystal ESR Properties of cis-Diammineplatinum a-Pyridone Blue" J. K. Barton, D. J. Szalda, H. N. Rabinowitz, J. V. Waszczak, and S. J. Lippard, J. Am. Chem. Soc., 101, 1434 (1979).
  • 1978

  • "Crystalline Platinum Blue: Its Molecular Structure, Chemical Reactivity, and Possible Relevance to the Mode of Action of Antitumor Platinum Drugs" J. K. Barton and S. J. Lippard, Ann. N.Y. Acad. Sci., 313, 686 (1978).
  • "Relationship of cis-Diammineplatinum a-Pyridone Blue to Other Platinum Blues. An X-ray Photoelectron Study" J. K. Barton, S. A. Best, S. J. Lippard, and R. A. Walton, J. Am. Chem. Soc., 100, 3785 (1978).
  • "Study of the Binding of cis- and trans-Dichlorodiammineplatinum(II) to Calf Thymus DNA by EXAFS Spectroscopy" B.-K. Teo, P. Eisenberger, J. Reed, J. K. Barton, and S. J. Lippard, J. Am. Chem. Soc., 100, 3225 (1978).
  • 1977

  • "Synthesis and Crystal Structure of cis-Diammineplatinum a-Pyridone Blue" J. K. Barton, H. N. Rabinowitz, D. J. Szalda, and S. J. Lippard, J. Am. Chem. Soc., 99, 2827 (1977).