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ZINN LAB PRIMER ON EMBRYONIC MOTOR AXON GUIDANCE
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Ozkan, E., Carrillo, R.A., Eastman, C.L., Weiszmann, R., Waghray, D., Johnson, K.G., Zinn, K., Celniker, S.E., and Garcia, K.C. (2013) An extracellular interactome of cell surface Immunoglobulin and Leucine-rich repeat proteins reveals novel receptor-ligand networks. Cell 154, 228-239.

Lee, H-K., Cording, A., Vielmetter, J., and Zinn, K. (2013) Interactions between a receptor tyrosine phosphatase and a cell surface ligand regulate axon guidance and glial-neuronal communication. Neuron 78, 813-826.

Carrillo, R.A., Menon, K., and Zinn, K. (2013) Is instability good for the brain? Neuron, 77, 599-600 (Review).

Menon, K.P., Carrillo, R.A., and Zinn, K. (2013) Development and plasticity of the Drosophila larval neuromuscular junction. WIREs Developmental Biology, doi: 10.1002/wdev.108 (Review).

Kurusu, M., Katsuki, T., Zinn, K., and Suzuki, E. (2012) Developmental changes in expression, subcellular distribution, and function of Drosophila N-cadherin are guided by cell-intrinsic programs during neuronal differentiation. Developmental Biology 366, 204-217.

Jeon, M., Scott, M.P., and Zinn, K. (2012) Interactions between Type III receptor tyrosine phosphatases and growth factor receptor tyrosine kinases regulate tracheal tube formation in Drosophila. Biology Open 1, 548-558.

Al-Anzi, B., and Zinn, K. (2011) Genetics of fat storage in flies and worms: What went wrong? (Review) Frontiers in Genetics 2, 87.

Sztul, T., Burgess, J., Jeon, M., Zinn, K., Marques, G., Brill, J., and Sztul, E. (2011) The Garz Sec7 domain guanine nucleotide exchange factor for ARF regulates salivary gland development in Drosophila.   Cellular Logistics 1, 69-76.

Wright, A.P., Fox, A.N., Johnson, K.G., and Zinn, K. (2010) Systematic screening of  Drosophila deficiency mutations for embryonic phenotypes and orphan receptor ligands.   PLoS ONE 5(8):e12288.

Al-Anzi, B., Armand, E., Nagamei, P., Olszewski, M., Sapin, V., Waters, C., Zinn, K., Wyman, R.J., and Benzer, S. (2010) The leucokinin pathway and its neurons regulate meal size in fruit flies.  Current Biology 20, 969-978.

 Al-Anzi, B., and Zinn, K. (2010) Colorimetric measurement of triglycerides cannot provide an accurate measure of stored fat content in DrosophilaPLoS ONE 5(8):e12353.

Salazar, A.M., Silverman, E.J., Menon, K.P, and Zinn, K. (2010)  Regulation of synaptic Pumilio function by an aggregation-prone domain.  Journal of Neuroscience 30, 515-522.

Lee, H-K., Wright, A.P., and Zinn, K. (2009) Live dissection of Drosophila embryos: streamlined methods for screening mutant collections by antibody staining.  Journal of Visualized Experiments 29;(34), pii: 1647. doi: 10.3791/1647.

Hong, W., Zhu, H., Potter, C.J., Barsh, G., Kurusu, M., Zinn, K., and Luo, L. (2009) Leucine-rich repeat transmembrane protein Capricious instructs discrete dendritic targeting in an olfactory map.   Nature Neuroscience, 12, 1542-1550. 

Wright, A.P., and Zinn, K. (2009) Guidance receptors find their places in the axonal order (Review).  Neuron 64, 150-152. 

Al-Anzi, B., Sapin, V., Waters, C., Zinn, K., Wyman, R.J., and Benzer, S. (2009) Obesity-blocking neurons in Drosophila Neuron 63, 329-341.

Jeon, M., and  Zinn, K. (2009). Receptor tyrosine phosphatases control tracheal tube geometries through negative regulation of Egfr signaling.  Development 136, 3121-3129.  

Zinn, K. (2009) Choosing the road less traveled by:  a ligand-receptor system that controls target recognition by Drosophila motor axons.  (Review).   Genes and Development 23, 1042-1045.

Bugga, L, Ratnaparkhi, A., and Zinn, K. (2009).  The cell surface receptor Tartan is a potential in vivo substrate for the receptor tyrosine phosphatase Ptp52F.  Molecular and Cellular Biology 29, 3390-3400.

Menon, K.P., Andrews, S., Murthy, M., Gavis, E.R., and Zinn, K. (2009).  The translational repressors Nanos and Pumilio have divergent effects on presynaptic terminal growth and postsynaptic glutamate receptor composition.  Journal of Neuroscience 29, 5558-5572.

Kurusu, M., Cording, A., Taniguchi, M., Menon, K.P., Suzuki, E., and Zinn, K. (2008) A screen of cell-surface molecules identifies leucine-rich repeat proteins as key mediators of synaptic target selection in the Drosophila neuromuscular system.  Neuron 59, 972-985.(plus an online supplement)

Jeon, M., Nguyen, H., Bahri, S., and Zinn, K. (2008).  Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily.  Neural Development 3, 3.

Kurusu, M., and Zinn, K. (2008) Receptor tyrosine phosphatases regulate birth order-dependent axonal fasciculation and midline repulsion during development of the Drosophila mushroom body. Molecular and Cellular Neuroscience 38, 5 3-65.

Ratnaparkhi, A., and Zinn, K. (2007) The secreted cell signal Folded Gastrulation regulates glial morphogenesis and axon guidance in Drosophila. Developmental Biology 308, 158–168

Fox, A.N., and Zinn, K. (2005) The transmembrane heparan sulfate proteoglycan Syndecan is an in vivo ligand for the DLAR receptor tyrosine phosphatase. Current Biology 15, 1701-1711. (plus an online supplement).

Sherwood, N.T., Sun, Q., Xue, M., Zhang, B., and Zinn, K. (2004) Drosophila Spastin regulates synaptic microtubule networks and is required for normal motor function. PLOS Biology 2, 2094-2111.

Menon, K., Sanyal, S. Habara, Y., Sanchez, R., Wharton, R.P., Ramaswami, M., and Zinn, K. (2004) The translational repressor Pumilio regulates presynaptic morphology and controls postsynaptic accumulation of translation factor eIF-4E. Neuron 44, 663-676.

Zinn, K. (2004) Dendritic tiling: new insights from genetics. Neuron 44, 211-213.

Kraut, R., and Zinn, K. (2004) Roundabout 2 regulates migration of sensory neurons by signaling in trans. Current Biology 14, 319-329.

Cepko, C.L., and Zinn, K. (2002) Development: an editorial overview. Current Opinion in Neurobiology 12, 11-13.

Schmid, A., Schindelholz, B., and Zinn, K. (2002) Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila. Trends in Neuroscience 25, 71-74.

Dubuque, S.H., Schachtner, J., Nighorn, A.J., Menon, K., Zinn, K., and Tolbert, L.P. (2001) Immunolocalization of synaptotagmin for the study of synapses in the developing antennal lobe of Manduca sexta. J. Comp. Neurol. 441, 277-287.

Schindelholz, B., Knirr, M., Warrior, R., and Zinn, K. (2001) Regulation of CNS and motor axon guidance in Drosophila by the receptor tyrosine phosphatase DPTP52F. Development 128, 4371-4382.

Kraut, R., Menon, K., and Zinn, K. (2001) A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila. Current Biology 11, 417-430. (plus an online supplement, pp. S1-S24).

Sun, Q., Schindelholz, B., Knirr, M., Schmid, A., and Zinn, K. (2001) Complex genetic interactions among four receptor tyrosine phosphatases regulate axon guidance in Drosophila. Molectular and Cellular Neuroscience 17, 274-291.

Sun, Q., Bahri, S., Schmid, A., Chia, W., and Zinn, K. (2000) Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo. Development 127, 801-812.

Zinn, K., and Schmid, A. (1999). Derailed axons get on track. (Review) Nature 402, 475-476.

Garrity, P.A., Lee, C-H., Salecker, I., Robertson, H., Desai, C.J., Zinn, K., and Zipursky, S.L. (1999) The Drosophila receptor protein tyrosine phosphatase DPTP69D is required for target selection by retinal axons. Neuron 22, 707-717.

Zinn, K., and Sun, Q. (1999) Slit branches out: a secreted protein mediates both attractive and repulsive axon guidance (Review). Cell 97, 1-4.

Desai, C.J., Garrity, P.A., Keshishian, H., Zipursky, S.L., and Zinn, K. (1999) The Drosophila SH2-SH3 adapter protein Dock is expressed in embryonic axons and facilitates synapse formation by the RP3 motoneuron. Development 126, 1527-1535.

Wills, Z., Marr, L., Zinn, K., Goodman, C.S., and Van Vactor, D. (1999) Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo. Neuron 22, 291-299.

Zinn, K. (1998) Receptor tyrosine phosphatases: the worm clears the picture (Review). Current Biology 8, 725-726.

Menon, K.P., and Zinn, K. (1998). Tyrosine kinase inhibition produces specific alterations in axon guidance in the grasshopper embryo. Development 125, 4121-4131.

Gindhart, J.G., Desai, C.J., Beushausen, S., Zinn, K., and Goldstein, L.S.B. (1998) Kinesin light chains are essential for axonal transport in Drosophila. J. Cell Biol. 141, 443-454.

Fashena, S.J., and Zinn, K. (1997) The transmembrane glycoprotein gp150 is a substrate for the receptor tyrosine phosphatase DPTP10D in Drosophila cells. Mol. Cell. Biol. 17, 6859-6867.

Zhang, Y., Chou, J.H., Bradley, J., Bargmann, C.I., and Zinn, K. (1997) The C. elegans 7-transmembrane protein ODR-10 functions as an odorant receptor in mammalian cells. Proc. Natl. Acad. Sci. USA 94, 12162-12167.

Condron, B.G., and Zinn, K. (1997) Regulated neurite tension as a mechanism for determination of neuronal arbor geometries in vivo. Current Biology 7, 813-816.

Desai, C.J., Krueger, N.X., Saito, H., and Zinn, K. (1997) Competition and cooperation among receptor tyrosine phosphatases control motoneuron growth cone guidance in Drosophila. Development 124, 1941-1952.

Bradley, J., Zhang, Y., Bakin, R., Lester, H.A., Ronnett, G.V., and Zinn, K. (1997) Functional expression of the heteromeric "olfactory" cyclic nucletotide-gated channel in the hippocampus: a potential effector of synaptic plasticity in brain neurons. J. Neurosci. 17, 1993-2005.

Desai, C.J., Sun, Q., and Zinn, K. (1997) Tyrosine phosphorylation and axon guidance: of flies and mice (Review). Current Opinion in Neurobiology 7, 70-74.

Desai, C.J., Gindhart, J.G., Goldstein, L.S.B., and Zinn, K. (1996) Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell 84, 599-609.

Tongiorgi, E., Bernhardt, R.R., Zinn, K., and Schachner, M. (1995) Tenascin-C messenger RNA is expressed in cranial neural crest cells, in some placodal derivatives, and in discrete domains of the embryonic zebrafish brain. J. Neurobiol. 28, 391-407.

Fashena, S.J., and Zinn, K. (1995) The ins and outs of receptor tyrosine phosphatases (Review). Current Biology 5, 1367-1369.

Condron, B.G., and Zinn, K. (1995) Activation of cAMP-dependent protein kinase triggers a glial-to-neuronal cell fate switch in an insect neuroblast lineage. Current Biology 5, 51-61.

Hamilton, B.A., Ho, A., and Zinn, K. (1995) Targeted mutagenesis and genetic analysis of a Drosophila receptor-linked protein tyrosine phosphatase gene. Roux's Arch. Dev. Biol. 204, 187-192.

Desai, C.J., Popova, E., and Zinn, K. (1994) A Drosophila receptor tyrosine phosphatase expressed in the embryonic CNS and larval optic lobes is a member of the set of proteins bearing the 'HRP' carbohydrate epitope. J. Neurosci. 14, 7272-7283.

Tian, S-S., and Zinn, K. (1994) An adhesion molecule-like protein that interacts with and is a substrate for a Drosophila receptor-linked protein tyrosine phosphatase. J. Biol. Chem.269, 28478-28486.

Condron, B.G., and Zinn, K. (1994) The grasshopper median neuroblast is a multipotent progenitor cell that generates glia and neurons in distinct temporal phases. J. Neurosci. 14, 5766-5777.

Condron, B.G., Patel, N.H., and Zinn, K. (1994) engrailed controls glial/neuronal cell fate decisions at the midline of the central nervous system. Neuron 13, 541-554.

Bradley, J., Li, J., Davidson, N., Lester, H.A., and Zinn, K. (1994) Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP. Proc. Natl. Acad. Sci. USA 91, 8890-8894.

Patel, N.H., Condron, B.G., and Zinn, K. (1994) Pair-rule expression patterns of even-skipped are found in both short and long germ beetles. Nature 367, 429-434.

Hamilton, B.A., and Zinn, K. (1994) From clone to mutant gene. in: Drosophila melanogaster: practical uses in cell and molecular biology. Edited by L.S.B. Goldstein and E.A. Fyrberg; Academic Press, Orlando, FL; pp. 81-94.

Zinn, K., and Condron, B.G. (1994) Cell fate decisions in the grasshopper central nervous system (Review). Current Opinion in Cell Biology 6, 783-787.

Uezono, Y., Bradley, J., Min, C., McCarty, N., Quick, M., Riordan, J.R., Chavkin, C., Zinn, K., Lester, H.A., and Davidson, N. (1993) Receptors that couple to two classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes. Receptors and Channels 1, 233-241.

Wang, W-C., Zinn, K., and Bjorkman, P.J. (1993) Expression and structural studies of fasciclin I, an insect cell adhesion molecule. J. Biol. Chem. 268, 1448-1455.

McAllister, L., Rehm, E.J., Goodman, C.S., and Zinn, K. (1992) Alternative splicing of micro-exons creates multiple forms of the insect cell adhesion molecule fasciclin I. J. Neurosci. 12, 895-905.

McAllister, L., Goodman, C.S., and Zinn, K. (1992) Dynamic expression of the cell adhesion molecule fasciclin I during embryonic development in Drosophila. Development 115, 267-276.

Tian, S-S., Tsoulfas, P., and Zinn, K. (1991) Three receptor-linked protein-tyrosine phosphatases are selectively expressed on central nervous system axons in the Drosophila embryo. Cell 67, 675-685.

 

 

 

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