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Selected Publications by Lab Members


Muhia M, Willadt S, Yee BK, Feldon J, Paterna JC, Schwendener S, Vogt K, Kennedy MB, and Knuesel I.Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockout. Learn Mem 19(7):268-81, 2012.

Li L, Stefan MI, and Le Novère N.Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKII. PLoS One 7(9):e43810, 2012.

Stefan MI, Marshall DP, and Le Novère N.Structural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKII. PLoS One 7(1):e29406, 2012.

Endler L, Stefan MI, Edelstein S, and and Le Novère N. Using chemical kinetics to model neuronal signalling pathways Computational Systems Neurobiology, (N. Le Novère, ed.), Springer, 2012


Carlisle HJ, Luong TN, Medina-Marino A, Schenker L, Khorosheva E, Indersmitten T, Gunapala KM, Steele AD, O'Dell TJ, Patterson PH, and Kennedy MB. Deletion of Densin-180 Results in Abnormal Behaviors Associated with Mental Illness and Reduces mGluR5 and DISC1 in the Postsynaptic Density Fraction. J Neurosci 31(45):16194-207, 2011.

Dall'Olio GM, Marino J, Schubert M, Keys KL, Stefan MI, Gillespie CS, Poulain P, Shameer K, Sugar R, Invergo BM, Jensen LJ, Bertranpetit J, and Laayouni H. Ten simple rules for getting help from online scientific communities. PLoS Comput Biol 7(9):e1002202, 2011.

Stefan MI, Pepke S, Mihalas S, Bartol T, Sejnowski T, and Kennedy MB. Multi-Stage Modeling of the Kinetics of Activation of CaMKII. Front Neuroinform, Conference Abstract: 4th INCF Congress of Neuroinformatics, 2011.


Marcora E, and Kennedy MB The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-κB from the synapse to the nucleus. Hum Mol Genet 19(22), 4373-84, 2010.

Pepke S, Kinzer-Ursem T, Mihalas S, and Kennedy MB. A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II. PLoS Comp Biol 6(2), e1000675, 2010.

Stefan MI. A cv of failures. Nature, 468: 467, 2010.

before 2010

Carlisle HJ, Manzerra P, Marcora E, and Kennedy MB. SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. J Neurosci 28(50), 13673-83, 2008.

Kennedy MB. Conserved and variable regions in the subunits of brain type II Ca2+/calmodulin-dependent protein kinase. Neuron. 60(3), 401-2, 2008.

Lucić V, Greif GJ, and Kennedy MB. Detailed state model of CaMKII activation and autophosphorylation. Eur Biophys J 38(1), 83-98, 2008.

Zhou Y, Takahashi E, Li W, Halt A, Wiltgen B, Ehninger D, Li GD, Hell JW, Kennedy MB, and Silva AJ. Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. J Neurosci 27(50), 13843-53, 2007.

Marcora E, Carlisle HJ, and Kennedy MB. The role of the postsynaptic density and the spine cytoskeleton in synaptic plasticity. In “Learning and Memory – A comprehensive reference”, edited by David Sweatt and John Byrnes, Elsevier Press, Oxford, 2007.

Korkin D, Davis FP, Alber F, Luong T, Shen M-Y, Lucic V, Kennedy MB, and Sali A. Modeling protein interactions by analogy: application to PSD-95. PloS Computational Biology 2: e153, 2006.

Shifman JM, Chois MH, Mihalas S, Mayo SL, and Kennedy MB. Ca2+/ calmodulin-dependent protein kinase II is activated by calmodulin with two bound calciums, Proc Natl Acad Sci USA 103, 13968-13973, 2006.

Kennedy MB, Beale HC, Carlisle HJ, and Washburn LR. Integration of biochemical signalling in spines, Nat Rev Neurosci 6, 423-434, 2005.

Carlisle HJ, and Kennedy MB. Spine Architecture and Synaptic Plasticity, Trends in Neurosci 28, 182-187, 2005.

Knuesel I, Elliott A, Chen H-J, Mansuy IM, and Kennedy, MB. A role for synGAP in regulating neuronal apoptosis, Eur J Neurosci 21, 611-621, 2005.

Vazquez LE, Chen H-J, Sokolova I, Knuesel I, Kennedy MB. SynGAP regulates spine formation, J Neurosci, 24, 8796-8805, 2004.

Oh JS, Manzerra P, and Kennedy MB. Regulation of the neuron-specific Ras GTPase activating protein, synGAP, by Ca2+/ calmodulin-dependent protein kinase II., J Biol Chem 279, 17980-17988, 2004.

Walikonis RS, Oguni A, Khorosheva EM, Jeng C-J, Asuncion FJ, and Kennedy, MB.   "Densin-180 forms a ternary complex with the a-subunit of CaMKII and alpha-actinin." Journal of Neuroscience 21, 423-433, 2001.

Kennedy MB.  "Signal processing machines at the postsynaptic density." Science 290, 750-754, 2000.

Walikonis RS, Jensen ON, Mann M, Provance DW Jr, Mercer JA, and Kennedy MB. "Identification of proteins in the postsynaptic density fraction by mass spectrometry." Journal of Neuroscience 20, 4069-4080, 2000.

Chen H-J, Rojas-Soto M, Oguni A, and  Kennedy MB.  "A synaptic Ras GTPase -activating protein (p135 SynGAP) inhibited by CaM kinase II."   Neuron  20, 895-904, 1998.

Kennedy MB. "Signal transduction molecules at the glutamatergic postsynaptic membrane." Brain Research Reviews 26, 243-257, 1998.

Kennedy MB. "The postsynaptic density at glutamatergic synapses."  Trends in Neuroscience 20, 264-268, 1997

Apperson ML, Moon I-S, and Kennedy MB.  "Characterization of Densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family."Journal of Neuroscience 16, 6839 6852, 1996.

Kornau H-C, Schenker LT, Kennedy MB, and Seeburg PH.  "Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95."  Science 269,1737-1740, 1995.

Cho K-O, Hunt CA, and Kennedy MB.  "The rat brain postsynaptic density fraction contains a homologue of the Drosophila  discs-large tumor suppressor protein." Neuron 9, 929-942, 1992.

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