Gene mappings

Symbol

Related Data Entries

Gene

GenBank

UniGene

Description

Notes

Probe

Chromosome

Chromosome Location

Cytoband

PubMed

Gene Ontology

Pathway

Gata3

GATA3; "GATA3* (different assay, 1 yr later)"; GATA.3; GATA.3.endog; GATA3b;

14462

NM_008091

Mm.313866

GATA binding protein 3

notes

1448886_at

2

-9778704

2 A1 2 7.0 cM

137

cell fate determination transcription regulation of transcription, DNA-dependent regulation of cytokine biosynthetic process norepinephrine biosynthetic process positive regulation of transcription, DNA-dependent sympathetic nervous system development nucleus DNA binding transcription factor activity protein binding zinc ion binding transcription activator activity sequence-specific DNA binding metal ion binding

Gfi1b

Gfi1B;

14582

NM_008114

Mm.373385

growth factor independent 1B

notes

1420399_at

2

-28464976

2 A3

19

zinc ion binding metal ion binding

Cd3g

CD3g;

12502

NM_009850

Mm.335106

CD3 antigen, gamma polypeptide

notes

1419178_at

9

-44777770

9 A5.2 9 26.0 cM

43

cell surface receptor linked signal transduction membrane integral to membrane alpha-beta T cell receptor complex receptor activity transmembrane receptor activity protein binding

Hematopoietic cell lineage T cell receptor signaling pathway

Bcl11b

Bcl11B; Bcl11b; Bcl11b (old primers);

58208

NM_001079883

Mm.392694

B-cell leukemia/lymphoma 11B

notes

1441762_at

12

-109148612

12 F1 12 52.0 cM

25

transcription regulation of transcription, DNA-dependent axonogenesis negative regulation of cell proliferation intracellular nucleus nucleic acid binding zinc ion binding metal ion binding

Bcl11a

Bcl11A;

14025

NM_016707

Mm.53687 Mm.447614

B-cell CLL/lymphoma 11A (zinc finger protein)

notes

1457072_at

11

23978116

11 A3.2

21

transcription regulation of transcription, DNA-dependent B cell differentiation T cell differentiation intracellular nucleus nucleic acid binding transcription corepressor activity zinc ion binding metal ion binding

Cpa3

CPA3;

12873

NM_007753

Mm.1135

carboxypeptidase A3, mast cell

notes

1448730_at

3

-20115521

3 A2 3 13.2 cM

22

proteolysis extracellular space carboxypeptidase activity carboxypeptidase A activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding

Renin-angiotensin system

Epor

EpoR;

13857

AK010968

Mm.2653

erythropoietin receptor

notes

1423344_at

9

-21763342

9 A3 9 5.0 cM

131

brain development heart development membrane integral to membrane receptor activity transmembrane receptor activity hematopoietin/interferon-class (D200-domain) cytokine receptor activity protein binding

Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage

Hoxb4

HoxB4;

15412

AV307188

Mm.3546

homeo box B4

notes

1460379_at

11

96180052

11 D 11 56.05 cM

91

transcription regulation of transcription, DNA-dependent multicellular organismal development pattern specification process organ morphogenesis regulation of transcription somatic stem cell division nucleus transcription factor complex DNA binding transcription factor activity sequence-specific DNA binding

Spib

SpiB; SpiB-2; SpiB-1;

272382

NM_019866

Mm.8012

Spi-B transcription factor (Spi-1/PU.1 related)

SpiB-2 transcription factor (Spi-1/PU.1 related) are Spi-B primers used in Yui & Rothenberg 2004 and in David-Fung et al 2006 SpiB-1 transcription factor (Spi-1/PU.1 related) are “MKA/CD” primers used in Dionne et al. 2005, Taghon et al 2006, Franco et al 2006

1460407_at

7

-51781364

7 B4

23

transcription regulation of transcription, DNA-dependent macrophage differentiation nucleus transcription factor complex DNA binding transcription factor activity sequence-specific DNA binding

Esr1

ESR1;

13982

NM_007956

Mm.9213 Mm.393566 Mm.450579

estrogen receptor 1 (alpha)

notes

1421244_at

10

-5342779

10 A1 10 12.0 cM

368

transcription regulation of transcription, DNA-dependent cell growth negative regulation of mitosis nucleus cytoplasm DNA binding transcription factor activity steroid hormone receptor activity receptor activity ligand-dependent nuclear receptor activity steroid binding protein binding zinc ion binding lipid binding transcription regulator activity sequence-specific DNA binding metal ion binding

Sbf1

SBF1;

77980

AV121839

Mm.35483

SET binding factor 1

notes

1434707_at

15

-89118666

15 F1

11

regulation of cell growth spermatogenesis phospholipid dephosphorylation pseudophosphatase activity inositol or phosphatidylinositol phosphatase activity

Ets1

Ets1;

23871

BC010588

Mm.292415

E26 avian leukemia oncogene 1, 5' domain

notes

1422027_a_at

9

32503626

9 A4 9 15.0 cM

104

regulation of progression through cell cycle transcription regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter cellular process positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter nucleus transcription factor complex DNA binding transcription factor activity protein binding sequence-specific DNA binding

Dorso-ventral axis formation Renal cell carcinoma

Ets2

Ets2;

23872

BB416434

Mm.290207

E26 avian leukemia oncogene 2, 3' domain

notes

1447685_x_at

16

95924092

16 C3-qter 16 69.6 cM

79

regulation of progression through cell cycle regulation of transcription, DNA-dependent cellular process intracellular nucleus DNA binding transcription factor activity sequence-specific DNA binding

Dorso-ventral axis formation

Elf4

Elf4; MEF (=Elf4); MEF;

56501

BB198529

Mm.36808 Mm.393394

E74-like factor 4 (ets domain transcription factor)

notes

1445778_at

X

-45766415

14

natural killer cell proliferation NK T cell proliferation transcription regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter nucleus DNA binding transcription factor activity calcium ion binding transcription activator activity sequence-specific DNA binding

Gfi1

Gfi1;

14581

NM_010278

Mm.2078 Mm.453139

growth factor independent 1

notes

1417679_at

5

-108145673

5 F 5 56.0 cM

46

transcription regulation of transcription, DNA-dependent mechanosensory behavior negative regulation of cell fate specification inner ear morphogenesis auditory receptor cell differentiation positive regulation of cell fate specification cell fate commitment intracellular nucleic acid binding DNA binding zinc ion binding metal ion binding

Id1

Id1;

15901

U43884

Mm.444

inhibitor of DNA binding 1

notes

1425895_a_at

2

152562009

2 H1 2 84.0 cM

97

negative regulation of transcription from RNA polymerase II promoter multicellular organismal development heart development BMP signaling pathway regulation of transcription regulation of angiogenesis nucleus protein binding transcription regulator activity

TGF-beta signaling pathway

Id2

Id2;

15902

BF019883

Mm.34871

inhibitor of DNA binding 2

notes

1435176_a_at

12

-25778663

12 B 12 7.0 cM

107

negative regulation of transcription from RNA polymerase II promoter multicellular organismal development heart development enucleate erythrocyte differentiation regulation of transcription positive regulation of macrophage differentiation lymph node development nucleus cytoplasm protein binding transcription regulator activity

TGF-beta signaling pathway

Id3

Id3;

15903

NM_008321

Mm.110

inhibitor of DNA binding 3

notes

1416630_at

4

135699736

4 D3 4 66.0 cM

78

negative regulation of transcription from RNA polymerase II promoter heart development epithelial cell differentiation regulation of transcription nucleus protein binding transcription factor binding protein domain specific binding transcription regulator activity

TGF-beta signaling pathway

Pou6f1

Pou6f1;

19009

AW824360

Mm.28825 Mm.449425

POU domain, class 6, transcription factor 1

notes

1444751_at

15

-100405748

15 F1 15 56.6 cM

24

transcription regulation of transcription, DNA-dependent regulation of transcription nucleus DNA binding transcription factor activity sequence-specific DNA binding

Runx1

Runx1;

12394

AB046930

Mm.4081 Mm.448569

runt related transcription factor 1

notes

1427847_at

16

-92604348

16 C4 16 62.2 cM

156

skeletal development transcription regulation of transcription, DNA-dependent hemopoiesis neuron differentiation positive regulation of angiogenesis behavioral response to pain neuron development nucleus DNA binding transcription factor activity protein binding ATP binding

Chronic myeloid leukemia Acute myeloid leukemia

Runx2

Runx2;

12393

AF005936

Mm.391013 Mm.391017

runt related transcription factor 2

notes

1426034_a_at

17

-44744853

17 B3 17 28.07 cM

262

skeletal development osteoblast differentiation osteoblast differentiation chondrocyte differentiation transcription regulation of transcription, DNA-dependent positive regulation of cell proliferation positive regulation of cell proliferation regulation of fibroblast growth factor receptor signaling pathway odontogenesis (sensu Vertebrata) regulation of odontogenesis (sensu Vertebrata) negative regulation of smoothened signaling pathway positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter cell maturation cell maturation nucleus cytoplasm DNA binding chromatin binding transcription factor activity protein binding ATP binding

Runx3

Runx3;

12399

NM_019732

Mm.378894

runt related transcription factor 3

notes

1421467_at

4

134676559

4 D3 4 65.7 cM

61

transcription regulation of transcription, DNA-dependent induction of apoptosis axon guidance hair follicle morphogenesis neurite development negative regulation of progression through cell cycle cell maturation negative regulation of epithelial cell proliferation nucleus DNA binding transcription factor activity ATP binding

Sfpi1

Sfpi1; PU.1 (=Sfpi1); PU.1; PU.1.endog; PU.1.coding;

20375

NM_011355

Mm.1302

SFFV proviral integration 1

one primer set exists that specifically detects endogenous PU.1, while another exists that detects the PU.1 coding sequence (transfected or endogenous)

1418747_at

2

90936953

2 E3 2 47.5 cM

171

transcription regulation of transcription, DNA-dependent lymphocyte differentiation macrophage differentiation granulocyte differentiation positive regulation of transcription, DNA-dependent nucleus transcription factor complex DNA binding transcription factor activity RNA binding protein binding transcription activator activity sequence-specific DNA binding

Acute myeloid leukemia

Zap70

Zap70;

22637

BB204558

Mm.8038

zeta-chain (TCR) associated protein kinase

notes

1440178_x_at

1

36818705

1 A4-C1 1 20.5 cM

59

protein amino acid phosphorylation signal transduction intracellular signaling cascade peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation beta selection positive thymic T cell selection positive thymic T cell selection negative thymic T cell selection thymic T cell selection positive regulation of T cell differentiation positive regulation of T cell differentiation positive regulation of alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation positive regulation of alpha-beta T cell proliferation protein amino acid autophosphorylation protein amino acid autophosphorylation positive regulation of calcium-mediated signaling T cell receptor signaling pathway cytoplasm cytosol T cell receptor complex nucleotide binding phosphotyrosine binding protein kinase activity protein-tyrosine kinase activity protein-tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity transferase activity

Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Lck

Lck;

16818

BB200032

Mm.293753

lymphocyte protein tyrosine kinase

notes

1457917_at

4

-129225601

4 D2.2 4 59.0 cM

175

protein amino acid phosphorylation intracellular signaling cascade regulation of T cell receptor signaling pathway release of sequestered calcium ion into cytosol membrane nucleotide binding protein kinase activity protein-tyrosine kinase activity protein binding ATP binding kinase activity transferase activity

Natural killer cell mediated cytotoxicity T cell receptor signaling pathway

Egr1

Egr1;

13653

NM_007913

Mm.181959

early growth response 1

notes

1417065_at

18

35020860

18 C/D 18 16.0 cM

172

negative regulation of transcription from RNA polymerase II promoter transcription regulation of transcription, DNA-dependent T cell differentiation intracellular nucleus nucleus nucleic acid binding DNA binding transcription factor activity zinc ion binding metal ion binding

Egr2

Egr2;

13654

X06746

Mm.290421

early growth response 2

notes

1427683_at

10

67000625

10 B5 10 35.0 cM

223

transcription regulation of transcription, DNA-dependent rhythmic behavior rhythmic behavior Schwann cell differentiation myelination regulation of transcription intracellular nucleus nucleus nucleic acid binding DNA binding transcription factor activity zinc ion binding transcription regulator activity metal ion binding

Egr3

Egr3;

13655

NM_018781

Mm.103737 Mm.440893

early growth response 3

notes

1421486_at

14

70477251

14 D2

29

transcription regulation of transcription, DNA-dependent neuromuscular synaptic transmission peripheral nervous system development intracellular nucleic acid binding DNA binding zinc ion binding metal ion binding

Sox4

Sox4;

20677

BF660472

Mm.240627 Mm.426716 Mm.455819

SRY-box containing gene 4

notes

1455867_at

13

-29042598

13 A3-A5 13 20.0 cM

51

transcription regulation of transcription, DNA-dependent exocrine pancreas development chromatin nucleus transcription factor complex DNA binding transcription factor activity transaminase activity transferase activity

Lat

Lat; LAT;

16797

AF036907

Mm.10280

linker for activation of T cells

notes

1460651_at

7

-133507341

7 F3

59

immune response cellular defense response signal transduction transmembrane receptor protein tyrosine kinase signaling pathway mast cell degranulation immunological synapse integral to plasma membrane membrane integral to membrane receptor signaling protein activity

Natural killer cell mediated cytotoxicity T cell receptor signaling pathway Fc epsilon RI signaling pathway

Notch1

Notch1;

18128

NM_008714

Mm.290610 Mm.392411

Notch gene homolog 1 (Drosophila)

notes

1418633_at

2

-26313544

2 A3 2 15.0 cM

394

cell fate specification epithelial to mesenchymal transition sprouting angiogenesis transcription regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter Notch signaling pathway multicellular organismal development determination of left/right symmetry compartment specification axonogenesis axonogenesis foregut morphogenesis endoderm development heart development positive regulation of cell proliferation epidermis development glial cell differentiation cell differentiation keratinocyte differentiation lung development embryonic limb morphogenesis forebrain development forebrain development hair follicle morphogenesis embryonic hindlimb morphogenesis anagen positive regulation of apoptosis positive regulation of apoptosis negative regulation of apoptosis cell fate commitment negative regulation of cell differentiation negative regulation of neuron differentiation positive regulation of transcription from RNA polymerase II promoter negative regulation of photoreceptor cell differentiation somatic stem cell division somatic stem cell division neuron fate commitment branching morphogenesis of a tube regulation of epithelial cell proliferation regulation of developmental process extracellular space nucleus cytoplasm integral to plasma membrane membrane integral to membrane DNA binding chromatin binding transcription factor activity receptor activity calcium ion binding protein binding metal ion binding

Dorso-ventral axis formation Notch signaling pathway

Notch3

Notch3;

18131

BB204535

Mm.439741

Notch gene homolog 3 (Drosophila)

notes

1443300_at

17

-32257837

17 B1 17 20.0 cM

104

transcription regulation of transcription, DNA-dependent Notch signaling pathway multicellular organismal development cell differentiation forebrain development negative regulation of cell differentiation negative regulation of neuron differentiation neuron fate commitment regulation of developmental process extracellular space integral to plasma membrane membrane integral to membrane DNA binding transcription factor activity receptor activity calcium ion binding protein binding

Dorso-ventral axis formation Notch signaling pathway

Hes1

Hes1; HES.1;

15205

BC018375

Mm.390859

hairy and enhancer of split 1 (Drosophila)

notes

1418102_at

16

30065442

16 B2 16 27.0 cM

147

negative regulation of transcription from RNA polymerase II promoter liver development transcription regulation of transcription, DNA-dependent cell adhesion positive regulation of cell proliferation pituitary gland development lung development auditory receptor cell differentiation auditory receptor cell fate determination cell fate commitment regulation of transcription negative regulation of cell differentiation negative regulation of auditory receptor cell differentiation negative regulation of neuron differentiation negative regulation of neuron differentiation cell maturation regulation of timing of cell differentiation nucleus cytoplasm DNA binding transcription repressor activity transcription regulator activity

Notch signaling pathway Maturity onset diabetes of the young

Nrarp

Nrarp;

67122

BI696369

Mm.46539

Notch-regulated ankyrin repeat protein

notes

1417985_at

2

25036277

2 A3

15

regulation of transcription, DNA-dependent cellular_component DNA binding transcription factor activity

Mitf

Mitf;

17342

BB763517

Mm.100641 Mm.333284 Mm.454504

microphthalmia-associated transcription factor

notes

1455214_at

6

97941785

6 D3 6 40.0 cM

254

transcription regulation of transcription, DNA-dependent multicellular organismal development sensory perception of sound Wnt receptor signaling pathway cell differentiation melanocyte differentiation regulation of cell proliferation regulation of apoptosis camera-type eye development pigmentation cell fate commitment regulation of transcription regulation of osteoclast differentiation regulation of osteoclast differentiation positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter nucleus nucleus DNA binding chromatin binding transcription factor activity RNA polymerase II transcription factor activity, enhancer binding transcription regulator activity

Melanogenesis Melanoma

Pax5

Pax5;

18507

AA185884

Mm.439659

paired box gene 5

notes

1459916_at

4

-44544377

4 B1 4 20.7 cM

102

transcription regulation of transcription, DNA-dependent multicellular organismal development spermatogenesis nervous system development organ morphogenesis cell differentiation nucleus transcription factor complex DNA binding transcription factor activity protein binding transcription activator activity transcription repressor activity

Nfe2

Nfe2;

18022

L09600

Mm.255151

nuclear factor, erythroid derived 2

notes

1452001_at

15

-103078648

15 F3 15 61.7 cM

54

regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter multicellular organismal development hemostasis circulation DNA binding transcription factor activity transcription coactivator activity

Fli1

Fli1;

14247

NM_008026

Mm.258908

Friend leukemia integration 1

notes

1422024_at

9

-32229792

9 A4 9 16.0 cM

47

transcription regulation of transcription, DNA-dependent circulation organ morphogenesis cellular process nucleus DNA binding transcription factor activity transcription activator activity sequence-specific DNA binding

Rag1

Rag1; Rag.1;

19373

NM_009019

Mm.828

recombination activating gene 1

notes

1450680_at

2

-101478410

2 E2 2 56.0 cM

304

DNA recombination B cell differentiation V(D)J recombination intracellular nucleic acid binding DNA binding nuclease activity endonuclease activity protein binding zinc ion binding hydrolase activity metal ion binding

Ptcra

Ptcra; pTalpha;

19208

NM_011195

Mm.215173

pre T-cell antigen receptor alpha

notes

1421760_at

17

-46892611

17 D-E1

39

extracellular space

Notch signaling pathway

Dbp

Dbp;

13170

BC018323

Mm.378235

D site albumin promoter binding protein

notes

1418174_at

7

52960601

7 B4 7 23.0 cM

28

transcription regulation of transcription, DNA-dependent circadian rhythm rhythmic process nucleus DNA binding transcription factor activity sequence-specific DNA binding protein dimerization activity

Klf13

Klf13;

50794

AK002926

Mm.240473

Kruppel-like factor 13

notes

1432543_a_at

7

-71036252

7 C

21

transcription regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter intracellular nucleic acid binding DNA binding DNA binding RNA polymerase II transcription factor activity RNA polymerase II transcription factor activity zinc ion binding metal ion binding

Ldb1

Ldb1;

16825

AF030333

Mm.327442

LIM domain binding 1

notes

1452024_a_at

19

-46107090

19 C3 19 46.0 cM

37

multicellular organismal development anterior/posterior axis specification gastrulation (sensu Mammalia) Wnt receptor signaling pathway neuron differentiation negative regulation of erythrocyte differentiation nucleus protein complex transcription cofactor activity LIM domain binding LIM domain binding protein homodimerization activity

Myst3

Myst3;

244349

BB387748

Mm.182776

MYST histone acetyltransferase (monocytic leukemia) 3

notes

1437487_at

8

23970010

8 A2

14

nucleosome assembly transcription regulation of transcription, DNA-dependent chromosome organization and biogenesis (sensu Eukaryota) chromatin modification somatic stem cell maintenance embryonic hemopoiesis nucleosome nucleus nucleus DNA binding histone acetyltransferase activity protein binding zinc ion binding acyltransferase activity transferase activity metal ion binding

Tyrosine metabolism Phenylalanine metabolism Glycerophospholipid metabolism 1- and 2-Methylnaphthalene degradation Benzoate degradation via CoA ligation Ethylbenzene degradation Limonene and pinene degradation Alkaloid biosynthesis II

Rnf149

Rnf149;

67702

T12280

Mm.28614

ring finger protein 149

notes

1429321_at

1

-39608145

1 B

15

ubiquitin cycle membrane integral to membrane protein binding zinc ion binding ligase activity metal ion binding

Thrap3

Thrap3;

230753

BC012655

Mm.29813 Mm.236211

thyroid hormone receptor associated protein 3

notes

1427408_a_at

4

-125841326

4 D2.2

14

transcription regulation of transcription, DNA-dependent transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter mediator complex mediator complex nucleotide binding transcription coactivator activity receptor activity ATP binding

Zfp109

Zfp109;

56869

NM_020262

Mm.103751

zinc finger protein 109

notes

1421711_at

7

-25012999

7 A3

4

regulation of transcription, DNA-dependent intracellular nucleic acid binding zinc ion binding metal ion binding

Zfp287

Zfp287;

170740

BI714160

Mm.339982

zinc finger protein 287

notes

1436220_at

11

-62524987

11 B2

11

transcription regulation of transcription, DNA-dependent regulation of cytokine biosynthetic process positive regulation of transcription intracellular nucleus nucleic acid binding DNA binding transcription factor activity zinc ion binding transcription activator activity metal ion binding

Zfp30

Zfp30;

22693

BB026234

Mm.292690

zinc finger protein 30

notes

1446313_at

7

30569808

7 B1 7 7.0 cM

12

transcription regulation of transcription, DNA-dependent intracellular nucleic acid binding DNA binding zinc ion binding metal ion binding

Zfp316

Zfp316;

54201

AF082568

Mm.6666

zinc finger protein 316

notes

1450151_at

5

-144013399

5 G2

3

transport membrane transporter activity zinc ion binding metal ion binding

Zfp358

Zfp358;

140482

BF449729

Mm.299073

zinc finger protein 358

notes

1451011_at

8

3493137

8 A1.1 8 1.0 cM

14

zinc ion binding metal ion binding

Zfp422

Zfp422;

67255

BC018339

Mm.18810

zinc finger protein 422

notes

1451244_a_at

6

-116574033

6 E3

16

transcription regulation of transcription, DNA-dependent odontogenesis intracellular nucleus nucleic acid binding DNA binding zinc ion binding metal ion binding

Zkscan1

Zkscan1; Kox18; Zkscan1(Kox18);

74570

AI509716

Mm.213114

zinc finger with KRAB and SCAN domains 1

notes

1429152_at

5

138526311

5 G1

13

transcription regulation of transcription, DNA-dependent intracellular nucleus nucleic acid binding DNA binding transcription factor activity zinc ion binding metal ion binding

Gata1

GATA.1;

14460

NM_008089

Mm.335973

GATA binding protein 1

notes

1449232_at

X

-7536385

X A2 X 1.9 cM

178

transcription regulation of transcription, DNA-dependent nucleus DNA binding transcription factor activity protein binding zinc ion binding sequence-specific DNA binding metal ion binding

Gata2

GATA.2;

14461

NM_008090

Mm.272747

GATA binding protein 2

notes

1450333_a_at

6

88148661

6 D1 6 38.5 cM

111

cell fate determination transcription regulation of transcription, DNA-dependent phagocytosis pituitary gland development cell differentiation neuron differentiation cell maturation nucleus DNA binding transcription factor activity protein binding zinc ion binding sequence-specific DNA binding metal ion binding

Lef1

LEF.1; Lef.1; LEF-1;

16842

NM_010703

Mm.255219

lymphoid enhancer binding factor 1

notes

1421299_a_at

3

130813388

3 G3 3 61.6 cM

152

negative regulation of transcription from RNA polymerase II promoter somitogenesis somitogenesis placenta development transcription regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter Wnt receptor signaling pathway dentate gyrus development hippocampus development regulation of Wnt receptor signaling pathway embryonic limb morphogenesis mammary gland development odontogenesis (sensu Vertebrata) negative regulation of striated muscle development positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter paraxial mesoderm formation cell development nucleus transcription factor complex cytoplasm DNA binding chromatin binding transcription factor activity RNA polymerase II transcription factor activity, enhancer binding protein binding DNA bending activity transcription activator activity

Wnt signaling pathway Adherens junction Melanogenesis Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia

Cd3e

CD3e;

12501

NM_007648

Mm.210361

CD3 antigen, epsilon polypeptide

notes

1422105_at

9

-44806825

9 A5.2 9 26.0 cM

99

cell surface receptor linked signal transduction positive regulation of T cell proliferation negative thymic T cell selection negative regulation of smoothened signaling pathway lymphocyte activation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling T cell receptor signaling pathway immunological synapse plasma membrane external side of plasma membrane external side of plasma membrane membrane integral to membrane T cell receptor complex alpha-beta T cell receptor complex signal transducer activity receptor activity transmembrane receptor activity protein binding

Hematopoietic cell lineage T cell receptor signaling pathway

Hbb-b1

Hbb.b1;

15129

AF071431

Mm.288567

hemoglobin, beta adult major chain

notes

1427866_x_at

7

-110961041

7 E3 7 50.0 cM

89

transport oxygen transport hemopoiesis mitochondrion hemoglobin complex oxygen transporter activity iron ion binding metal ion binding

Cebpa

C.EBPa;

12606

BC011118

Mm.349667

CCAAT/enhancer binding protein (C/EBP), alpha

notes

1418982_at

7

35904311

7 B1 7 12.0 cM

159

liver development embryonic placenta development transcription regulation of transcription, DNA-dependent mitochondrion organization and biogenesis negative regulation of cell proliferation cytokine and chemokine mediated signaling pathway myeloid cell differentiation macrophage differentiation lung development regulation of cell proliferation fat cell differentiation cell maturation nucleus transcription factor complex DNA binding transcription factor activity protein binding protein homodimerization activity sequence-specific DNA binding protein dimerization activity

Acute myeloid leukemia

Cebpb

C.EBPb; C/EBPbeta;

12608

NM_009883

Mm.439656

CCAAT/enhancer binding protein (C/EBP), beta

notes

1418901_at

2

167514414

2 H3 2 95.5 cM

171

embryonic placenta development transcription regulation of transcription, DNA-dependent anti-apoptosis induction of apoptosis neuron differentiation regulation of interleukin-6 biosynthetic process fat cell differentiation positive regulation of transcription nucleus cytoplasm DNA binding transcription factor activity protein binding transcription activator activity protein homodimerization activity sequence-specific DNA binding protein heterodimerization activity protein dimerization activity

Tcf12

HEB; HEBcan; HEBAlt; HEBCan;

21406

NM_011544

Mm.171615

transcription factor 12

notes

1445093_at

9

-71693559

9 D 9 42.0 cM

43

transcription regulation of transcription, DNA-dependent regulation of transcription from RNA polymerase II promoter multicellular organismal development regulation of transcription nucleus transcription factor complex DNA binding protein binding transcription activator activity transcription regulator activity

Ikzf2

Helios;

22779

BB291816

Mm.106343

IKAROS family zinc finger 2

notes

1456956_at

1

-69583963

1 C3

14

transcription regulation of transcription, DNA-dependent intracellular transcription factor complex nucleic acid binding DNA binding transcription factor activity zinc ion binding metal ion binding

Ikzf1

Ikaros;

22778

AV317621

Mm.103545

IKAROS family zinc finger 1

notes

1436312_at

11

11586215

11 A1 11 6.0 cM

78

transcription regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent negative regulation of transcription hemopoiesis forebrain development positive regulation of body size positive regulation of body size positive regulation of transcription positive regulation of transcription from RNA polymerase II promoter gland development intracellular nucleus transcription factor complex transcription factor complex centric heterochromatin nucleic acid binding DNA binding transcription factor activity protein binding zinc ion binding transcription repressor activity metal ion binding

Ikzf3

Aiolos;

22780

BB202216

Mm.133367

IKAROS family zinc finger 3

notes

1441088_at

11

-98326006

11 D

20

transcription regulation of transcription, DNA-dependent intracellular transcription factor complex nucleic acid binding DNA binding transcription factor activity protein binding zinc ion binding metal ion binding

Ikzf4

Zfpn1a4; Eos;

22781

NM_011772

Mm.358648

IKAROS family zinc finger 4

notes

1460664_at

10

-128069470

10 D3

13

negative regulation of transcription, DNA-dependent nucleus nucleic acid binding protein binding transcription repressor activity

Dtx1

Deltex.1; Deltex1;

14357

AI551217

Mm.1645

deltex 1 homolog (Drosophila)

notes

1458643_at

5

-121130272

5 F 5 65.0 cM

24

Notch signaling pathway Notch signaling pathway glial cell differentiation nucleus protein binding zinc ion binding metal ion binding

Notch signaling pathway

Mpl

TpoR;

17480

AF360122

Mm.4864

myeloproliferative leukemia virus oncogene

notes

1451919_a_at

4

-118115019

4 D 4 56.5 cM

63

regulation of progression through cell cycle regulation of transcription, DNA-dependent cellular process extracellular space intracellular membrane integral to membrane transcription factor activity receptor activity hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Cytokine-cytokine receptor interaction Jak-STAT signaling pathway

Csf2ra

Csf2ra1;

12982

BM941868

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

notes

1420703_at

19

-61300313

19 D3 19 51.0 cM

27

extracellular space membrane integral to membrane receptor activity hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage

Ccdc88c

Daple;

68339

NM_026681

Mm.156217

coiled-coil domain containing 88C

notes

1442862_at

12

-102150909

12 E

11

regulation of protein amino acid phosphorylation Wnt receptor signaling pathway protein destabilization negative regulation of frizzled signaling pathway protein homooligomerization insoluble fraction PDZ domain binding protein self-association

Unk

Zc3h5;

217331

NM_172569

Mm.297706 Mm.427777

unkempt homolog (Drosophila)

notes

1426681_at

11

115891635

11 E2

13

electron transport nucleic acid binding protein binding zinc ion binding electron carrier activity heme binding metal ion binding

Zscan21

Zipro-1;

22697

NM_011757

Mm.2760

zinc finger and SCAN domain containing 21

notes

1416370_at

5

138558132

5 G2 5 78.0 cM

19

transcription regulation of transcription, DNA-dependent multicellular organismal development spermatogenesis cell differentiation positive regulation of transcription, DNA-dependent oogenesis intracellular nucleus nucleic acid binding DNA binding transcription factor activity zinc ion binding transcription activator activity metal ion binding

Tsc22d1

TSC-22;

21807

AU016382

Mm.153272

TSC22 domain family, member 1

notes

1433899_x_at

14

76815627, 76904371

14 D3 14 42.0 cM

28

transcription regulation of transcription, DNA-dependent nucleus transcription factor activity

Tal1

SCL;

21349

NM_011527

Mm.439685

T-cell acute lymphocytic leukemia 1

notes

1449389_at

4

114732131

4 D1 4 49.5 cM

114

transcription regulation of transcription, DNA-dependent multicellular organismal development hemopoiesis cell differentiation erythrocyte differentiation erythrocyte differentiation cell fate commitment regulation of transcription nucleus protein complex DNA binding protein binding transcription regulator activity

Tcfe2a

E2A;

21423

NM_011548

Mm.3406

transcription factor E2a

notes

1426297_at

10

-79872337

10 C1 10 43.0 cM

112

transcription regulation of transcription, DNA-dependent regulation of transcription nucleus transcription factor complex DNA binding transcription factor activity protein binding transcription regulator activity protein homodimerization activity protein heterodimerization activity

Zfpm1

FOG.1;

22761

NM_009569

Mm.390068

zinc finger protein, multitype 1

notes

1423603_at

8

124806040

8 E1

23

negative regulation of transcription from RNA polymerase II promoter transcription regulation of transcription, DNA-dependent heart development intracellular nucleus nucleic acid binding DNA binding transcription corepressor activity protein binding zinc ion binding metal ion binding

Ebf1

EBF;

13591

NM_007897

Mm.439662 Mm.440346

early B-cell factor 1

notes

1448293_at

11

44431635

11 B1.1 11 20.0 cM

76

transcription regulation of transcription, DNA-dependent multicellular organismal development regulation of transcription positive regulation of transcription nucleus DNA binding transcription factor activity protein binding protein binding zinc ion binding transcription regulator activity metal ion binding

Atxn2l

Ataxin2-like;

233871

NM_021477

Mm.231450

ataxin 2-like

notes

1456476_at

7

-133635221

7 F3

12

biological_process membrane molecular_function

Tpsb2

Mcpt6;

17229

NM_010781

Mm.7409

tryptase beta 2

notes

1422180_a_at

17

25503277

17 A3.3 17 10.39 cM

28

proteolysis inflammatory response extracellular region extracellular space serine-type endopeptidase activity protein binding heparin binding peptidase activity hydrolase activity tryptase activity

Itgam

Mac.1;

16409

NM_008401

Mm.262106

integrin alpha M

notes

1422046_at

7

135206153

7 F4

120

cell adhesion integrin-mediated signaling pathway neutrophil chemotaxis cellular extravasation activated T cell proliferation nucleus integrin complex external side of plasma membrane membrane integral to membrane opsonin binding opsonin binding receptor activity calcium ion binding protein binding

Cell adhesion molecules (CAMs) Hematopoietic cell lineage Leukocyte transendothelial migration Regulation of actin cytoskeleton

Myb

c.Myb;

17863

BC011513

Mm.52109 Mm.432826

myeloblastosis oncogene

notes

1422734_a_at

10

-20844735

10 A3 10 16.0 cM

176

regulation of progression through cell cycle G1/S transition of mitotic cell cycle transcription regulation of transcription, DNA-dependent regulation of transcription, DNA-dependent calcium ion transport cellular process regulation of transcription nucleus DNA binding transcription factor activity transcription factor activity protein binding transcription regulator activity

Tcf7

TCF.1; Tcf7.e7-8; Tcf7.e4-6; Tcf7.8; TCF.7.8; Tcf7.3;

21414

NM_009331

Mm.31630

transcription factor 7, T-cell specific T-cell transcription factor 1 (TCF-1)

TCF.1 is the name of the protein encoded by the gene “Tcf7”. Tcf7.e7-8: exons “7-8” actually 5-6 Tcf7.e4-6:Bad primers Tcf7.8 f & r cover protein coding exon 6 of 9 (N-terminus of HMG box) (NB used in Tydell et al 2007 and in David-Fung et al. 2006 and in Franco et al 2006) Tcf7.3 crosses protein coding exons 3 & 4 out of 9; exon 3 includes part of b-catenin binding domain. (NB used in Taghon et al 2005)

1450461_at

11

-52066105

11 B1.3 11 28.0 cM

66

transcription regulation of transcription, DNA-dependent Wnt receptor signaling pathway neural tube development embryonic genitalia morphogenesis regulation of cell proliferation regulation of apoptosis embryonic digestive tract morphogenesis embryonic hindgut morphogenesis nucleus transcription factor complex DNA binding transcription factor activity

Wnt signaling pathway Adherens junction Melanogenesis Colorectal cancer Endometrial cancer Prostate cancer Thyroid cancer Basal cell carcinoma Acute myeloid leukemia

Il7r

IL7ra; IL7Ra;

16197

AI573431

Mm.389

interleukin 7 receptor

Notes

1448575_at

15

-9435913

15 A1 15 4.6 cM

122

cell surface receptor linked signal transduction lymph node development external side of plasma membrane membrane integral to membrane receptor activity hematopoietin/interferon-class (D200-domain) cytokine receptor activity interleukin receptor activity

Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage

Zfp407

Zfp407.5;

240476

AW547438

Mm.329575

zinc finger protein 407

notes

1459998_at

18

18 E4

10

biological_process cellular_component molecular_function

83 Genes