Bi250c Topics in Systems Neuroscience
Spring 2015
Instructor: Thanos Siapas
TA: Kevin Shan
Class Time: Fri 2:00-4:55pm in 101 Kerckhoff
Apr 3
Week 1: Introduction
Optional Reading
- Cole and Curtis (1939), Electric impedance of the squid giant axon during activity
- Hodgkin et al. (1952), Measurement of current-voltage relations in the membrane of the giant axon of Loligo
- Hodgkin et al. (1952), Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
- Hodgkin et al. (1952), The components of membrane conductance in the giant axon of Loligo
- Hodgkin et al. (1952), The dual effect of membrane potential on sodium conductance in the giant axon of Loligo
- Hodgkin et al. (1952), A quantitative description of membrane current and its application to conduction and excitation in nerve
- Huxley (2002), From overshoot to voltage clamp
- Squid and giant nerve fiber videos
Apr 10
Week 2: Plasticity
- (A) Markram et al. (1997), Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
- (B) Cassenaer & Laurent (2007), Hebbian STDP in mushroom bodies facilitates the synchronous flow of olfactory information in locusts, supplementary
- (C) Yao & Dan (2001), Stimulus Timing-Dependent Plasticity in Cortical Processing of Orientation
Apr 17
Week 3: Hippocampus and space
- (C) O'Keefe & Recce (1993), Phase Relationship Between Hippocampal Place Units and the EEG Theta Rhythm
- (A) Harvey et al. (2009), Intracellular dynamics of hippocampal place cells during virtual navigation, supplementary
- (B) Ziv et al. (2013), Long-term dynamics of CA1 hippocampal place codes, supplementary, movie
Apr 24
Week 4: Traveling waves
- (B) Prechtl et al. (1997), Visual stimuli induce waves of electrical activity in turtle cortex
- (C) Watt et al. (2009), Traveling waves in developing cerebellar cortex mediated by asymmetrical Purkinje cell connectivity, supplementary, movie 1, 2, 3
- (A) Lubenov & Siapas (2009), Hippocampal theta oscillations are travelling waves, supplementary, movie 1, 2, 3
May 1
Week 5: Structure/function
- (A) Rancz et al. (2011), Transfection via whole-cell recording in vivo: bridging single-cell physiology, genetics and connectomics, supplementary
- (C) Brigmann, Helmstaedter & Denk (2011), Wiring specificity in the direction-selectivity circuit of the retina, supplementary, image data
- (B) Maisak et al. (2013), A directional tuning map of Drosophila elementary motion detectors, supplementary
May 15
May 22
Week 8: 3-layer cortex comparison
- (A) Haberly (2001), Parallel-distributed Processing in Olfactory Cortex: New Insights from Morphological and Physiological Analysis of Neuronal Circuitry
- (B) Treves et al. (2008), What is the mammalian dentate gyrus good for?
- (C) Fournier et al. (2015), Looking for the roots of cortical sensory computation in three-layered cortices
May 29
Week 9: Ripples
June 5
Week 10: Final Projects
Contact
Mailing list
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caltech.eduInstructor Thanos Siapas: thanos
caltech.edu