Bi250b
Topics in Systems Neuroscience
Winter, 2007
Class Time: Wed 2:00-3:55 in 101 Kerckhoff
Mailing List Sign-Up : bi250bmailcaltech.edu

Instructors
Gilles Laurent : laurentgcaltech.edu
Thanos Siapas : thanoscaltech.edu

TA
Casimir Wierzynski : casimircaltech.edu
Other years: 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Group lists

Jan 3: lecture
First meeting & Introduction

Jan 10: lecture
Tuning curves, maps, and codes.


Jan 17:
Part 1 Guest lecture by Mala Murthy (post-doc, Laurent Lab) on genetic techniques in systems neuroscience
Part 2 Student presentation: Two-photon imaging
  1. (A) Ohki et al. (2005), Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex
  2. (B) Yaksi and Friedrich (2006), Reconstruction of firing rate changes across neuronal populations by temporally deconvolved Ca++ imaging
  3. (B) Zipfel et al. (2003), Nonlinear magic: multiphoton microscopy in the biosciences

Jan 24: student presentation
Brain maps
  1. (B) Cohen and Knudsen (1999), Maps versus clusters: different representations of auditory space in the midbrain and forebrain
  2. (A) Kohonen and Hari (1999), Where the abstract feature maps of the brain might come from
  3. (A) Durbin and Mitchison (1990), A dimension reduction framework for understanding cortical maps

Jan 31: student presentation
Spatial maps
  1. (B) Hargreaves et al. (2005), Major dissociation between medial and lateral entorhinal input to dorsal hippocampus
    [supplementary material]
  2. (B) Fyhn et al. (2004), Spatial representation in the entorhinal cortex
    [supplementary material]
  3. (A) Hafting et al. (2005), Microstructure of a spatial map in the entorhinal cortex
    [supplementary material 1] [2] [3] [4] [5] [6] [7] [8] [9] [10]

Feb 7: student presentation
Spike timing dependent plasticity
  1. (A) Markram et al. (1997), Regulation of Synaptic Efficacy by Coincidence of Postsynaptic APs and EPSPs
  2. (A) Froemke and Dan (2002), Spike-timing-dependent synaptic modification induced by natural spike trains
  3. (B) Roberts and Bell (2002), Spike timing dependent synaptic plasticity in biological systems

Feb 14: student presentation
Dopamine and learning
  1. (A) Schultz et al. (1997), A Neural Substrate of Prediction and Reward
  2. (B) Pan et al. (2005), Dopamine cells repond to predicted events during classical conditioning: evidence for eligibility traces in the reward-learning network
  3. (B) Horvitz (2000), Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events

Feb 21: student presentation
Neural oscillations
  1. (A) Shadlen and Movshon (1999), Synchrony Unbound: A Critical Evaluation of the Temporal Binding Hypothesis
  2. (B) Perez-Orive et al. (2002), Oscillations and Sparsening of Odor Representations in the Mushroom Body
  3. (A) Buzsaki and Draguhn (2004), Neuronal Oscillations in Cortical Networks

Feb 28: student debate
Synfire in the hole
  1. (A) Ikegaya et al. (2001), Synfire Chains and Cortical Songs: Temporal Modules of Cortical Activity
  2. (B) Mokeichev et al. (2007), Stochastic Emergence of Repeating Cortical Motifs in Spontaneous Membrane Potential Fluctuations In Vivo
  3. (B) McLelland and Paulsen (2007), Cortical Songs Revisited: A Lesson in Statistics

Mar 7: student presentation
Sleep
  1. (B) Louie and Wilson (2001), Temporally Structured Replay of Awake Hippocampal Ensemble Activity during Rapid Eye Movement Sleep
  2. (A) Siegel (2001), The REM Sleep-Memory Consolidation Hypothesis
  3. (A) Crick and Mitchison (1983), The function of dream sleep


Group A Flora, Janet, Sina, Todd, Liming
Group B Dan, Melanie, Klaus, Ilana, Alana, Edwin

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