Definitions for Life Stages in WormBase

term: all stages
goid: LS:0000002
definition: All C. elegans development stages, including embryo, larva and adult stage.
definition_reference: wb:wjc
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term: embryo
goid: LS:0000003
definition: The whole period of embryogenesis, from the formation of an egg till its hatch.
definition_reference: wb:wjc
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term: proliferating embryo
goid: LS:0000004
definition: 0-350min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 560 cells. From start of first cleavage till cleavage is over.
definition_reference: wb:wjc
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term: blastula embryo
goid: LS:0000005
definition: 0-100min after first cleavage at 20 Centigrade. Proliferate from 1 cell to 28 cells. From first cleavage till the start of gastrulation.
definition_reference: wb:wjc
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term: 1-cell embryo
goid: LS:0000006
definition: Also called zygote. -50min till 0min of first cleavage at 20 Centigrade. Contains 1 cell.
definition_reference: wb:wjc
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term: 2-cell embryo
goid: LS:0000007
definition: 0-20min after first cleavage at 20 Centigrade. Contains 2 cells.
definition_reference: wb:wjc
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term: 4-cell embryo
goid: LS:0000008
definition: 20-40min after first cleavage at 20 Centigrade. Contains 4 cells.
definition_reference: wb:wjc
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term: 28-cell embryo
goid: LS:0000009
definition: 100-105min after first cleaveage at 20 Centigrade. Contains 28 cells.
definition_reference: wb:wjc
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term: gastrulating embryo
goid: LS:0000010
definition: 100-290min after first cleavage at 20 Centigrade. Proliferate from 28 cells to 421 cells. Referring to the whole period of gastrulation.
definition_reference: wb:wjc
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term: 51-cell embryo
goid: LS:0000011
definition: 120-135min after first cleavage at 20 Centigrade. Contains 51 cells.
definition_reference: wb:wjc
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term: 88-cell embryo
goid: LS:0000012
definition: 145-150min after first cleavage at 20 Centigrade. Contains 88 cells.
definition_reference: wb:wjc
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term: enclosing embryo
goid: LS:0000013
definition: 290-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage when embryo just finished gastulation and is enclosing.
definition_reference: wb:wjc
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term: late cleavage stage embryo
goid: LS:0000014
definition: 210-350min after first cleavage at 20 Centigrade. Proliferate from 421 cells to 560 cells. The stage before the fast cleavage of cells finishes.
definition_reference: wb:wjc
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term: elongating embryo
goid: LS:0000015
definition: 350-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The stage that embryo starts elongation till elongation is over.
definition_reference: wb:wjc
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term: bean embryo
goid: LS:0000016
definition: 350-390min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. Emrbyo elongation started but have not formed comma shape yet. The shape of embryo looks like a lima bean. A stage right before comma embryo. Also called lima embryo or lima bean stage.
definition_reference: wb:wjc
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term: comma embryo
goid: LS:0000017
definition: 390-420min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo looks like a comma. A stage between bean embryo and 1.5-fold embryo.
definition_reference: wb:wjc
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term: 1.5-fold embryo
goid: LS:0000018
definition: 420-460min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and fold back 50%. A stage between comma embryo and 2-fold embryo.
definition_reference: wb:wjc
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term: 2-fold embryo
goid: LS:0000019
definition: 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.
definition_reference: wb:wjc
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term: 3-fold embryo
goid: LS:0000020
definition:520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.
definition_reference: wb:wjc
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term: fully-elongated embryo
goid: LS:0000021
definition: 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.
definition_reference: wb:wjc
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term: postembryonic
goid: LS:0000022
definition: The stage after hatch till death.
definition_reference: wb:wjc
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term: larva
goid: LS:0000023
definition: From the time after hatch till becomes adult.
definition_reference: wb:wjc
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term: L1 larva
goid: LS:0000024
definition: The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.
definition_reference: wb:wjc
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term: L1-L2 molt
goid: LS:0000026
definition: The stage when an animal shifts from L1 larva to L2 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L1-L2 lethargus
goid: LS:0000025
definition: The stage during L1-L2 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L1-L2 ecdysis
goid: LS:0000042
definition: The stage during L1-L2 molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L1-L2d molt
goid: LS:0000043
definition: The stage when an animal shifts from L1 larva to L2d larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L1-L2d lethargus
goid: LS:0000044
definition: The stage during L1-L2d molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L1-L2d ecdysis
goid: LS:0000045
definition: The stage during L1-L2d molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L2 larva
goid: LS:0000027
definition: The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.
definition_reference: wb:wjc
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term: L2-L3 molt
goid: LS:0000029
definition:The stage when an animal shifts from L2 larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L2-L3 lethargus
goid: LS:0000028
definition: The stage during L2-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L2-L3 ecdysis
goid: LS:0000047
definition: The stage during L2-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L2d larva
goid: LS:0000046
definition: A special second stage larva with altered physiology and developmental potential that leads to formation of dauer larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.
definition_reference: ISBN 0-87969-433-5
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term: L2d-dauer molt
goid: LS:0000031
definition:The stage when an animal shifts from L2d larva to dauer larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L2d-dauer lethargus
goid: LS:0000030
definition: The stage during L2d-dauer molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L2d-dauer ecdysis
goid: LS:0000048
definition: The stage during L2d-dauer molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L2d-L3 molt
goid: LS:0000053
definition: The stage when an animal shifts from L2d larva to L3 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L2d-L3 lethargus
goid: LS:0000054
definition:The stage during L2d-L3 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L2d-L3 ecdysis
goid: LS:0000055
definition: The stage during L2d-L3 molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: dauer larva
goid: LS:0000032
definition: A third stage larva specialized for dispersal and long term survival.
definition_reference: ISBN 0-87969-433-5
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term: post dauer stage
goid: LS:0000052
definition: The stage right after an animal recovered from dauer but has not started transformation to L4 larva yet.
definition_reference: wb:wjc
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term: postdauer-L4 molt
goid: LS:0000034
definition: The stage when an animal shifts from post dauer stage to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: postdauer-L4 lethargus
goid: LS:0000033
definition: The stage during postdauer-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: postdauer-L4 ecdysis
goid: LS:0000051
definition: The stage during postdauer-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L3 larva
goid: LS:0000035
definition: The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.
definition_reference: wb:wjc
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term: L3-L4 molt
goid: LS:0000037
definition: The stage when an animal shifts from L3 larva to L4 larva. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L3-L4 lethargus
goid: LS:0000036
definition:The stage during L3-L4 molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L3-L4 ecdysis
goid: LS:0000049
definition:The stage during L3-L4 molt, after the brief lethargus period, when an animal sheds off old cuticle.
definition_reference: wb:wjc
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term: L4 larva
goid: LS:0000038
definition:The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.
definition_reference: wb:wjc
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term: L4-adult molt
goid: LS:0000040
definition:The stage when an animal shifts from L4 larva to adult. It includes the synthesis of new cuticle, cease of phrayngeal pumping during a lethargus stage, and the shed off of old cuticle.
definition_reference: wb:wjc
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term: L4-adult lethargus
goid: LS:0000039
definition: The stage during L4-adult molt when an animal becomes lethargic, ceases pharyngeal pumping and synthesizes new cuticle under the old.
definition_reference: wb:wjc
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term: L4-adult ecdysis
goid: LS:0000050
definition: The stage during L4-adult molt, after the brief lethargus period, when an animal shed off old cuticle.
definition_reference: wb:wjc
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term: adult
goid: LS:0000041
definition: The stage after an animal is fully-developed and reaches maturity.
definition_reference: wb:wjc
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term: adult male
goid: WBls:0000056
definition: The stage after an male animal is fully-developed and reaches maturity.
definition_reference: wb:wjc
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term: adult hermaphrodite
goid: WBls:0000057
definition: The stage after an hermaphrodite animal is fully-developed and reaches maturity.
definition_reference: wb:wjc
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term: pre-reproductive stage adult hermaphrodite
goid: WBls:0000058
definition: Very young adult hermaphrodites that do not have eggs in the uterus yet. At 20 Centigrade: 0 - 13 hours after L4-adult molt. 3 days after first cleaveage.
definition_reference: wb:wjc
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term: reproductive stage adult hermaphrodite
goid: WBls:0000060
definition: Adult hermaphrodites continuously laying fertilized eggs. hermaphrodite in egg laying stages--ususally up to 4/5 days after L4-adult molt at Centigrade. From the first fertilized egg is laid, til all sperms are used. At 20 Centigrade: 13 hours after L4-adult molt until about 5.4 days after the L4-adult molt. 3-8.4 days after first cleavage.
definition_reference: wb:wjc
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term: oocyte-laying stage adult hermaphrodite
goid: WBls:0000061
definition: When egg-laying is still going on but intermittent and during which a significant number of oocytes are laid. Included in reproductive stage adult hermaphrodite.
definition_reference: wb:wjc
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term: post-reproductive stage adult hermaphrodite
goid: WBls:0000062
definition: Adult hermaphrodites that contain no more sperm, thus stop egg-laying, but still alive. At 20 Centigrade: 5.4 days after L4-adult molt until the death. 8.4 - 13.2 (average wild type life span) days after first cleavage.
definition_reference: wb:wjc
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term: newly molted young adult hermaphrodite
goid: WBls:0000063
definition: At 20 Centigrade: 0-24 hours after L4-adult molt.
definition_reference: wb:wjc
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term: 1-day post-L4 adult hermaphrodite
goid: WBls:0000064
definition: At 20 Centigrade: 24-48 hours after L4-adult molt. 4-5 days after first cleavage.
definition_reference: wb:wjc
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term: 2-days post-L4 adult hermaphrodite
goid: WBls:0000065
definition: At 20 Centigrade: 48-72 hours after L4-adult molt. 5-6 days after first cleavage.
definition_reference: wb:wjc
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term: 3-days post-L4 adult hermaphrodite
goid: WBls:0000066
definition: At 20 Centigrade: 72-96 hours after L4-adult molt. 6-7 days after first cleavage.
definition_reference: wb:wjc
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term: 4-days post-L4 adult hermaphrodite
goid: WBls:0000067
definition: At 20 Centigrade: 96-120 hours after L4-adult molt. 7-8 days after first cleavage.
definition_reference: wb:wjc
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term: 5-days post-L4 adult hermaphrodite
goid: WBls:0000068
definition: At 20 Centigrade: 5-6 days after L4-adult molt. 8-9 days after first cleavage.
definition_reference: wb:wjc
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term: 4-7 days post-L4 adult hermaphrodite
goid: WBls:0000069
definition: At 20 Centigrade: 4-7 days after L4-adult molt. 7-10 days after first cleavage.
definition_reference: wb:wjc
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term: 7-10 days post-L4 adult hermaphrodite
goid: WBls:0000070
definition: At 20 Centigrade: 7-10 days after L4-adult molt. 10-13 days after first cleavage. Usually this is the end of wild type C. elegans life span.
definition_reference: wb:wjc
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