| .............................................................. Sangdun Choi, Ph.D. |
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| AfCS (Alliance for
Cellular Signaling) Nature AfCS/Nature 2003 Meeting AfCS Newsletter
DNA Microarray Genome Project BAC (Bacterial Artificial
Chromosome) Signal Transduction Systems Biology About Me
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Division of Biology 147-75, California Institute of Technology, Pasadena, CA 91125, USA Tel: Int+(626)395-8732(office), (626)395-3789(lab), Fax: Int+(626)796-7066, E-mail: schoi@caltech.edu ............................................................... Sangdun Choi is working at Caltech and expanding his understanding of bacterial artificial chromosomes (BAC) in plants to include bacterial and mammalian systems. Sangdun was instrumental in the construction of a complete human BAC library for the Human Genome Project. Sangdun then became involved in his second consortium, the Alliance for Cellular Signaling (AfCS). He is excited about stepping into the DNA microarray and RNA interference fields. Spearheading the AfCS’ projects, Sangdun has provided hundreds of gene expression profiles from B cells exposed to various ligands. Sangdun says he is now “swamped with millions of bits of information from the arrays but has no simple way of extracting the networks of signaling links from the information.” This is one of the major and most immediate challenges of the AfCS. Sangdun is thoughtful and sees science as a way to answer many of life’s questions. He is determined to extract meaning from gene expression data. Can we change our biological makeup so we can become smarter, healthier, and live longer? Sangdun hopes his works might answer some of the questions. from AfCS Newsletter
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