Categories of genes among differentially expressed genes in the brain
117 genes were annotated and classified based on molecular function among the 455 total genes identified
to be differentially enriched in our screen (117 / 455 = 26%)
Guidelines from the Gene Ontology (GO) Consortium were followed
Amy Cb Hpc OB PAG total
enriched genes 33 159 89 101 73 455
# annotated genes 8 47 17 24 21 117
%annotated genes / enriched 24 30 19 24 29 26
molecular function total # genes % genes % in Amy % in Cb % in Hpc % in OB % in PAG
motor protein 1 1 13 0 0 0 0
ribonuclear 2 2 0 4 0 0 0
nuclear 1 1 0 2 0 0 0
signaling 30 26 25 30 0 29 33
transporter 3 3 0 4 0 0 5
ligand binding or carrier 8 7 0 9 6 8 5
DNA binding 20 17 50 17 12 17 10
structural 10 9 0 6 18 17 0
enzyme 18 15 0 15 18 8 29
enzyme inhibitor 4 3 0 4 0 4 5
membrane protein 6 5 13 4 0 4 10
ubiquitin 2 2 0 0 6 4 0
immunity, defense protein 1 1 0 0 6 0 0
zinc finger protein 2 2 0 0 12 0 0
cell adhesion 1 1 0 0 6 0 0
chaperone 1 1 0 0 6 0 0
translation 5 4 0 2 6 8 5
cell cycle regulator 1 1 0 2 0 0 0
transcription factor binding 1 1 0 0 6 0 0