PLOTS. (A) Distribution of normalized average difference
(
) values in each sample. Only
the 11ka array is plotted here, but all other chips had similar distributions.
The histogram describes a unimodal distribution, wherein the bulk of the mRNA
species are of relatively low abundance. Only a minority of the mRNA species
were highly expressed. These results are in agreement with previous estimates
of mRNA abundance and complexity in other tissues (1, 2).For clarity, only values below 7000 are shown.
The dotted line indicates the mean value (1104). Bin size= 200
1. Lewin (2000) Genes VII (Oxford University Press).
2. Zhang, L., Zhou, W., Velculescu, V., Kern, S., Hruban, R., Hamilton, S., Vogelstein, B. & Kinzler, K. (1997) Science 276, 1268-1272.
(B) Plots of average difference values for all possible 2-way comparisons. The first row has the amygdala (A) on the x-axis. The second row are plots with the cerebellum on the x-axis, the third and fourth rows have the hippocampus and olfactory bulb, respectively, on the x-axis. The y-axes are the cerebellum (C), hippocampus (H), olfactory bulb (O) and PAG (P), from the first to fourth columns, respectively. For clarity, average difference values were divided by 1000 and only values below 30,000 are shown. The dashed line indicates a slope = 1.
