Caltech Bi 211 Fall 1999
Revised 10/13/99
Course
announcement
Tentative
Schedule
Requirements
Session 5
Tuesday
10/26
7:00 PM
|
Voltage-gated
Channels
|
Magdalena Bak
Tim McGarvey
|
Readings in Hille
This topic is Hille's specialty; and the book presents lots of excellent
and important information.
Chapter 2
Chapters 4 and 5
Chapter 9: 250-258.
Chapter 14
Optional: Chapters 17, 18
Additional Required Readings
Siegel, M. S. and E. Y. Isacoff 1997. A genetically encoded optical probe
of membrane voltage. Neuron. 19:735-41.
ReprintLocal
version
Will GFP be the Molecule of the Year? Perhaps; even if not,
it can be incorporated into a channel and serves as a voltage sensor.
Doyle, D., J. M. Cabral, R. Pfuetzner, A. Kuo, J. Gulbis, S. Cohen,
B. Chait and R. MacKinnon 1998. The structure of the potassium channel:
molecular basis of K+ conduction and selectivity. Science. 280:69-77.
(7 Megabytes!!) Reprint
Local
version
The paper we awaited for 20 years.