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CURRICULUM VITAE |
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Name: |
Haijiang Cai |
Address: |
Department of Physiology & Biophysics Zilkha Neurogenetic 1501 San Pablo St. ZNI 323 |
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E-mail: |
hcai@usc.edu |
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Tel: |
1-323-442-0099
(lab) |
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Fax: |
1-323-442-4466
(lab) |
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Web: |
http://www-scf.usc.edu/~hcai |
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Research Interests
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Molecular mechanisms of synaptic transmission and its
regulation |
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·
How neural circuits process information and control
behavior |
Education
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2001 - 2007 |
Ph.D., Department of Physiology and
Biophysics, Advisor: Dr. Robert H. Chow Dissertation: Role of Complexin in
Regulated Exocytosis |
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1996 - 2001 |
B.S., School of Life Science,
University of Science & Technology of China (USTC), Hefei, P. R. China. Advisor: Dr. Xu Zhang ( Dissertation: delta-Opioid Receptor
Mediated Neuropeptide Release |
Research Experiences
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2001-Present |
Research Assistant of Dr. Robert H. Chow's lab, Department of
Physiology and Biophysics, Zilkha Neurogenetic Institute, Keck School of
Medicine, |
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2000 - 2001 |
Undergraduate Research Assistant of Dr. Xu Zhang's Sensory
System Laboratory, |
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1999 - 2000 |
Undergraduate Research Assistant of Dr. Zhuan Zhou's Cellular
Biophysics Laboratory, USTC, |
Major Achievements in PhD Study
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Demonstrated that complexin is a positive regulator for Ca2+-triggered
exocytosis. |
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Demonstrated that complexin functions at vesicle priming
step. |
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Shown that phosphorylation of complexin S93 is required
for the priming function of complexin. |
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Developed the caged-calcium photolysis technique, which is
the first time in Dr. Robert Chow’s lab. |
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Combined the caged-calcium photolysis system with TIRF
system, which we are optimizing now (collaborate with Wenyong Xiong). |
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Developed the mouse adrenal chromaffin cell culture
method, which allows us to get sufficient healthy cells from a single mouse. |
Publications
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1. |
Bao L,
Wang HF, Cai HJ, Tong YG,
Jin SX, Lu YJ, Grant G, Hokfelt T, and Zhang X. Peripheral axotomy induces
only very limited sprouting of coarse myelinated afferents into inner lamina II
of rat spinal cord. Eur J Neurosci 16: 175-185, 2002. |
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2. |
Bao L,
Jin SX, Zhang C, Wang LH, Xu ZZ, Zhang FX, Wang LC, Ning FS, Cai HJ, Guan JS, Xiao HS, Xu
ZQ, He C, Hokfelt T, Zhou Z, and Zhang X. Activation of delta opioid
receptors induces receptor insertion and neuropeptide secretion. Neuron
37: 121-133, 2003. |
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3. |
Michael
DJ, Cai H, Xiong W, Ouyang
J, and Chow RH. Mechanisms of peptide hormone secretion. Trends Endocrinol Metab
17:408-415, 2006. |
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4. |
Kolski-Andreaco A, Cai
H, Currle DS, Chandy KG, and Chow RH. Mouse Adrenal Chromaffin Cell
Isolation. Journal of Visualized Experiments 1(2), 2007. |
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5. |
Cai H, Reim K,
Varoqueaux F, Tapechum S, Hill K, Brose N, Sorensen J, and Chow RH. Complexin
II Enhances Chromaffin Cell Vesicle Priming for Exocytosis. submitted, 2007. |
Abstracts and Presentations
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1. |
Role of
complexin in regulated exocytosis. USC PHBI Retreat, presentation. 2006 |
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2. |
Cai H, Reim K, Brose N, and Chow RH.
Role of complexin in synaptic transmission. Neuronal Circuits: From Structure to Function, |
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3. |
Cai H, Reim K, Varoqueaux F, Tapechum
S, Brose N, Sorensen J, and Chow RH. Complexin Regulates Vesicle Exocytosis
at Priming Steps in Chromaffin Cells. 51st
Annual Meeting of Biophysical Society, |
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4. |
Lin M-Y,
Xiong W, Cai H, Reim K,
Brose N, Ko C-P, and Chow RH. Complexin I is a positive regulator of
neuromuscular transmission. The 37th
annual meeting of the Society for Neuroscience, |
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5. |
Cai H, Reim K, Varoqueaux F, Tapechum
S, Brose N, Sorensen J, and Chow RH. Complexin II, a positive regulator of
exocytosis, facilitates vesicle priming. The
37th annual meeting of the Society for Neuroscience, |
Recent Honors and Awards
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2006 |
USC GPSS
Spring 2006 Travel Awards |
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2006 |
Financial
Assistance to the CSHL Neural Circuits Meeting |
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2001 - 2007 |
Research
Assistantship, |
Memberships
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2007 - |
Member of the Society for Neuroscience |
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2003 - |
Member of the American Association for
the Advancement of Science (AAAS) |
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2002 - 2003 |
Member of the National Geographic
Society |
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1997 - 2001 |
Member of Scientific Investigation and
Exploration Association of USTC |
Other Activities
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2006 |
Assistant to the Audio Visual Department during the
Neural Circuits Meeting, |
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1997 - 2000 |
Coeditor of Message of the League, a weekly magazine of USTC |
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1997 - 1998 |
Secretary of Propaganda in the Student Association
of |
References
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Available upon request |