Bi/CNS 150: Introduction to Neuroscience

Ralph Adolphs and Henry Lester
Fall 2015


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Catalog Description

Bi/CNS 150. Neurobiology. 10 units (4-0-6); first term. General principles of the function and organization of nervous systems, providing both an overview of the subject and a foundation for advanced courses. Topics include the physical and chemical bases for action potentials, synaptic transmission, and sensory transduction; anatomy; development; sensory and motor pathways; memory and learning at the molecular, cellular, and systems level; and the neuroscience of brain diseases. Instructors: Adolphs and Lester.

Lectures will be held at MWF 11-12 in the 1st Floor Broad Center Lecture Hall.

Contacts

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MondayTuesdayWednesday ThursdayFriday
9/28/2015 9/29/2015 9/30/2015 10/1/2015 10/2/2015

Introduction to the Course: The Evolution of Neurons, Brains, and Minds

(Lester & Adolphs)

Anatomy of the Central Nervous System

(Adolphs)

Discussion Section

Development 1

(Adolphs)

Ch. 1: p. 5-10

Problem Set 0 Out

Ch. 15: p. 337-344

Ch. 52: p. 1165-1185
Ch. 53: p. 1187-1194, 1218-1227

10/5/2015 10/6/2015 10/7/2015 10/8/2015 10/9/2015

Voltage-Dependent Channels and Action Potentials 1

(Lester)

Voltage-Dependent Channels and Action Potentials 2

(Lester)

Discussion Section

Synapses 1: Presynaptic Transmitter Release

(Lester)

Ch. 5, 6, & 7

Problem Set 1 Out

Ch. 5, 6, & 7

Ch. 5, 6, & 7

10/12/2015 10/13/2015 10/14/2015 10/15/2015 10/16/2015

Synapses 2: The Acetylcholine Receptor and Organization of the Nerve-Muscle Synapse

(Lester)

Problem Set 1 Due at 4:30pm

Glutamate Receptors in the CNS

(Lester)

Discussion Section

Development 2

(Lester)

Ch. 12

Problem Set 2 Out

Ch. 12

Ch. 9

10/19/2015 10/20/2015 10/21/2015 10/22/2015 10/23/2015

Inhibition, Electrical Integration of Signals, and Cable Properties of Dendrites and and Axons

(Lester)

Problem Set 2 Due at 4:30pm

Inward Rectifiers and Glia

(Lester)

Discussion Section

The G Protein Pathway in Neuroscience

(Lester)

Ch. 10: p. 211–227

Problem Set 3 Out

Ch. 2: p. 28–35
Ch. 10: 227–232

Ch. 11

10/26/2015 10/27/2015 10/28/2015 10/29/2015 10/30/2015

Recreational Drugs

(Lester)

Problem Set 3 Due at 4:30pm

Vision 1: The Visual System from Retina to Visual Cortex

(Adolphs)

Vision 2: The Retina and Detection of Light

(Lester)

Kandel Ch. 11
Alberts Ch. 15

Midterm Out

Ch. 25

Ch. 26: p. 577-586

11/2/2015 11/3/2015 11/4/2015 11/5/2015 11/6/2015

Vision 3: Higher-level Vision and Object Recognition

(Adolphs)

Midterm Due at 4:30pm

The Motor System

(Lester)

Discussion Section

The Olfactory System

(Lester)

Ch. 26: p. 577-602
Ch. 27 & 28

Ch. 14, p. 309
Ch. 34, 35, 37, & 38

Ch. 32: p. 712–726

11/9/2015 11/10/2015 11/11/2015 11/12/2015 11/13/2015

The Auditory System

(Adolphs)

The Somatosensory System

(Adolphs)

Discussion Section

Learning & Memory 1: Types of Memory, Declarative Memory, and the Hippocampus

(Adolphs)

Ch. 30 & 31

Problem Set 4 Out

Ch. 22: p. 475–480, 491–495
Ch. 23: p. 498–504, 510–521
Ch. 24: 530–535, 541–553

Ch. 65, 66, & 67

11/16/2015 11/17/2015 11/18/2015 11/19/2015 11/20/2015

Learning & Memory 2: Cellular Mechanisms and Synaptic Plasticity

(Lester)

Problem Set 4 Due at 4:30pm

Learning & Memory 3: Nondeclarative Memory and Modulation

(Adolphs)

Discussion Section

Neurodegenerative Disease: Alzheimer’s & Parkinson's disease

(Lester)

Ch. 65: p. 1441–1447
Ch. 66: p. 1461–1472, 1478–1485
Ch. 67: p. 1510–1519

Problem Set 5 Out

Ch. 65: p. 1441–1447
Ch. 66: p. 1461–1472, 1478–1485
Ch. 67: p. 1510–1519

Ch. 43
Ch. 44: p. 1002–1012
Ch. 59

11/23/2015 11/24/2015 11/25/2015 11/26/2015 11/27/2015

Emotion and Social Behavior

(Adolphs)

Problem Set 5 Due at 4:30pm

Autism

(Adolphs)

Thanksgiving Holiday

Thanksgiving Holiday

Ch. 47: p. 1056–1061
Ch. 48

Problem Set 6 Out

Ch. 64: p. 1425–1434

11/30/2015 12/1/2015 12/2/2015 12/3/2015 12/4/2015

Aminergic Systems, Mood and Depression

(Lester)

Problem Set 6 Due at 4:30pm

Schizophrenia

(Lester)

Discussion Section

The Future

(Lester & Adolphs)

Ch. 63: p. 1402–1418

Ch. 62

Final Out
12/7/2015 12/8/2015 12/9/2015 12/10/2015 12/11/2015

Final Due at 4:30pm