Projects in the BI Pilot Program

Rapid, Systematic Identification of Genomic Regulatory Elements Controlling Region- and Neuron-Subtype-Specific Gene Expression in Mammalian Brain, David Anderson, PI. 2004-2006.

Automated High-Throughput Behavior Capture and Screening, Alan Barr, PI. 2004-2009

Development of Cryoelectron Tomography as a General Method to Image Complex Biochemical Reactions, Grant Jensen, PI. 2004-2007 (became the Beckman Resource Center for Transmission Electron Microscopy).

Novel Protein Technologies, David Tirrell, PI. 2004-2007.

Hybridization Chain Reaction, Niles Pierce, PI. 2005-2013 (became the Programmable Molecular Technology Center).

Coupled Flow Cytometry and Isotope-ratio Mass Spectrometry, Alex Sessions, PI. 2005-2009.

Spin-Polarized Molecules for Structural and Systems Biology, Dan Weitekamp, PI. 2006-2009.

Sequence Census Assays for Genome-Wide Gene Network Studies, Barbara Wold, PI. 2008-2009 (became the Functional Genomics Resource Center).

Molecular Sensor Foundry, Christina Smolke, PI. 2008-2009 (PI left Caltech).

A New Method for High-Throughput Production of Monoclonal Antibodies Against All Cell Surface and Secreted Proteins Within a Species, Kai Zinn, PI. 2011-2015.

Beckman Institute Optogenetics Neuroscience Initiative and CLARITY Center (BIONICenter), Viviana Gradinaru, PI. 2012-2015 (became the CLOVER Resource Center).

Neuro/Nano Large Scale Integration, Michael Roukes and Thanos Siapas, PIs. 2013-2016.

Super-resolution Fluorescence In Situ Hybridization Microscopy, Long Cai, PI. 2013-2016.