Cell Type Specific Log10 QPCR Expression Values

Synonym	Cell Type	QPCR Expression	Normalized To	Data From
PU.1	CD4	-3.57	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD4	-5.58	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD4	-3.72	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	CD4_24-	-4.23	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD4_24-	-4.47	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	CD4_69-	-4.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD4_69-	-5.72	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	CD8	-3.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD8	-5.37	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD8	-2.89	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	CD8_24-	-4.27	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD8_24-	-4.04	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	CD8_69-	-4.19	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	CD8_69-	-4.77	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN1	-0.8	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN1	-0.74	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN1	-0.68	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN1	-0.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN1	-1.31	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN1	-1.57	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN1	-1.54	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1 (=Sfpi1)	DN1	-0.59	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU.1 (=Sfpi1)	DN1	-0.3	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU1 e1-2	DN1	-0.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN1	-0.89	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN2	-1.54	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2	-1.22	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2	-1.85	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN2	-1.8	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN2	-2.26	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1 (=Sfpi1)	DN2	-1.08	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU.1 (=Sfpi1)	DN2	-0.75	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU1 e1-2	DN2	-1.68	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN2	-1.42	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN2	-1.23	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN2a	-1	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2a	-1.14	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2a	-0.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2a	-1.04	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN2a	-1.12	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN2a	-1.36	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN2b	-1.66	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN2b	-1.52	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN3a	-2.49	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3a	-2.25	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3a	-2.49	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3a	-3.52	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3a	-1.74	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3a	-3.24	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN3a	-3.01	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN3a	-3.17	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1 (=Sfpi1)	DN3a	-2.44	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU.1 (=Sfpi1)	DN3a	-2.03	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU1 e1-2	DN3a	-2.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3a	-3.62	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3a	-2.03	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3a	-2.21	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN3b	-3.42	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3b	-3.3	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3b	-2.41	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DN3b	-4	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN3b	-4.12	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN3b	-4.7	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1 (=Sfpi1)	DN3b	-3.01	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU.1 (=Sfpi1)	DN3b	-2.69	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU1 e1-2	DN3b	-3.04	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3b	-3.58	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3b	-2.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DN3b	-2.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DN4	-4.12	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN4	-5.52	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	DN4	-4.04	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1 (=Sfpi1)	DN4	-3.14	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
PU.1 (=Sfpi1)	DN4	-3.78	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
PU.1	DP	-4.62	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DP	-5.06	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DP	-4.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	DP69-	-4.82	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	DP69-	-2.77	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DP69-	-5.02	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	DP69-	-4.23	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	GDT	-2.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU.1	GDT	-3.49	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	GDT	-3.09	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
PU1 e1-2	GDT	-4.24	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
PU.1	LSK-	-1.92	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK-	-1.82	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK-	-1.66	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK-	-5.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK-	-5.52	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK-	-4.8	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
PU.1	LSK+	-1.38	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK+	-1.39	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK+	-1.33	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK+	-5.3	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK+	-4.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	LSK+	-5.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
PU.1	PreM	-0.59	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	PreM	-0.89	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	PreM	-0.89	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	PreM	-4.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	PreM	-4.55	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	PreM	-4.2	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
PU.1	ProB	-1.66	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProB	-2.02	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProB	-1.68	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProB	-6.05	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProB	-6.05	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProB	-5.4	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
PU.1	ProT	-5.4	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProT	-6.05	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
PU.1	ProT	-6.1	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)

Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
PU.1.coding	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
PU.1.coding	LZ_noDL	0.02	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
.
PU.1.coding	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	DL_PU1	1.98	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	DL_PU1	1.86	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	DL_PU1	1.73	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_LZ	0.08	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_LZ	0.1	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_LZ	-0.12	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_PU1	1.78	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_PU1	1.92	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.coding	noDL_PU1	1.82	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
.
PU.1.coding	Prmtv_LZ	0.73	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	Prmtv_LZ	0.35	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	Prmtv_PU1	2.3	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	Prmtv_PU1	2.04	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_PU1	2.21	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_PU1	2.2	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	ProT_PU1	2.24	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_LZ	-0.93	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_LZ	-1.21	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_LZ	-0.21	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_PU1	2.48	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_PU1	2.02	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
PU.1.coding	PreT_PU1	2.26	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
.
PU.1.endog	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
PU.1.endog	LZ_noDL	-0.26	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
.
PU.1.endog	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	DL_PU1	0.08	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	DL_PU1	0.02	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	DL_PU1	0.69	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_LZ	-0.15	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_LZ	-0.21	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_LZ	-0.41	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_PU1	-0.02	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_PU1	0.29	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
PU.1.endog	noDL_PU1	0.51	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
.
PU.1	BM	0.74	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
PU.1	Fliver	0.39	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
PU.1	Mast	0.97	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
PU.1	Fthymus	0.36	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
PU.1	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
PU.1	LZ_noDL	-0.06	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
PU.1	LZ_DL	0	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
PU.1	G3_DL	-0.86	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
PU.1	KRRm_DL	-0.67	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
PU.1	LZ_noDL	-0.06	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
PU.1	G3_noDL	-1.16	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
PU.1	KRRm_noDL	-0.7	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
PU.1	PROMOTES	PU.1	Franco et al 2006 PNAS (very weak, borderline in thymocytes); Okuno, Y.,et al.: Tenen, Mol Cell Biol. 2005 Apr;25(7):2832-45.; H. Chen,et al.: Tenen Oncogene. 1995 Oct 19;11(8):1549-60
Runx3	PROMOTES	PU.1	possible interpretation of expression pattern in view of Huang, G.et al.: Tenen Nat Genet. 2008 Jan;40(1):51-60.
GATA-3	REPRESSES	PU.1	Taghon et al 2007, Nat. Immunol.; Hernandez-Hoyos et al 2003, Immunity; MK Anderson et al. 2002, Developmental Biol.; Scripture-Adams, D. D. & EVR, unpublished; Zarnegar, M. A. & EVR, unpublished
Runx+coactivator	PROMOTES	PU.1	Okada, H.et al.: Satake Oncogene. 1998 Nov 5;17(18):2287-93; Huang, G.et al.: Tenen Nat Genet. 2008 Jan;40(1):51-60.
DN2, DN3 Stage Negative Regulator	REPRESSES	PU.1	Anderson et al. 1999 Development; Anderson et al 2002 Immunity; Spain, L. M et. al.: Scott, J Immunol. 1999 Sep 1;163(5):2681-7; Lefebvre, J.M.et al.: Wiest J Immunol. 2005 May 15;174(10):6184-94.; David-Fung et al 2006 Immunol. Rev.
Runx + corepressor	REPRESSES	PU.1	M. Zarnegar unpublished; Huang, G.et al.: Tenen Nat Genet. 2008 Jan;40(1):51-60.
PU.1	REPRESSES	Id1	Franco et al PNAS 2006
PU.1	REPRESSES	GATA-1 antagonized by PU.1 (net GATA-1)	bubble= net GATA-1 activity; Rekhtman, N. et al.: Skoultchi, Genes Dev. 1999 Jun 1;13(11):1398-411; Zhang, P.et al.: Tenen, Blood. 2000 Oct 15;96(8):2641-8.
PU.1	PROMOTES	PU.1 antagonized by GATA-1 (net PU.1)	by definition
PU.1	PROMOTES	Other Myeloid Genes	Friedman,A.D. Oncogene. 2007 Oct 15;26(47):6816-28