| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|---|---|---|
| Positive inputs | PROMOTES | Runx+coactivator | Contextual inputs needed to direct Runx effect |
| Runx1 | PROMOTES | Runx+coactivator | by definition |
| Runx+coactivator | PROMOTES | PU.1 | Okada, H.et al.: Satake Oncogene. 1998 Nov 5;17(18):2287-93; Huang, G.et al.: Tenen Nat Genet. 2008 Jan;40(1):51-60. |