| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|---|---|---|
| Tcr-Beta | PROMOTES | Rearranged-TCR-Beta | by definition |
| RAG-1 | PROMOTES | Rearranged-TCR-Beta | major role in T-cell development |
| Rearranged-TCR-Beta | PROMOTES | Pre-TCR | Rate limiting component of pre-TCR |