| Synonym | Perturbation | QPCR Expression | Relative To | Data From |
|---|
| Pax5 | BM | 3.37 | Thymus | GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | Mast | 1.24 | Thymus | GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | Fthymus | 1.48 | Thymus | GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol) |
| . | | | | |
| Pax5 | LZ_DL | 0 | LZ,DL | Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | LZ_noDL | 0.79 | LZ,DL | Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol) |
| . | | | | |
| Pax5 | LZ_DL | 0 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | G3_DL | -0.22 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | KRRm_DL | -0.06 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | LZ_noDL | 0.79 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | G3_noDL | 0.57 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Pax5 | KRRm_noDL | 0.51 | LZ,DL | Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol) |
| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|
| EBF antagonized by Notch signaling (Net EBF) | PROMOTES | Pax5 | Bubble = net EBF escaping Notch inhibition |
| E2A.E2A | PROMOTES | Pax5 | Hagman, J., & Lukin, K. Curr Opin Immunol. 2006 Apr;18(2):127-34 |
| Pax5 | PROMOTES | CD19 | Cobaleda, C. & Busslinger, M. Nat Immunol. 2007 May;8(5):463-70. |
| Pax5 | PROMOTES | EBF | Roessler, S.,et al.: Grosschedl, Mol Cell Biol. 2007 Jan;27(2):579-94 |
| Pax5 | REPRESSES | Notch1 | Souabni, A. et al.: Busslinger, Immunity. 2002 Dec;17(6):781-93. |
| Pax5 | PROMOTES | Other B-cell Different'n Genes | Cobaleda, C. & Busslinger, M. Nat Immunol. 2007 May;8(5):463-70. |