| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|---|---|---|
| PU1 activity | PROMOTES | PU.1 modulated by Notch | PU.1 over expression data |
| PU.1 modulated by Notch | REPRESSES | Bcl11B | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | c-Myb | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | Ets1 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | FOG-1 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | Gfi1 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | HEB | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | PROMOTES | Id2 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | Ikaros | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | LAT | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | Lck | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | RAG-1 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | TCF-1 | Franco et al PNAS 2006 |
| PU.1 modulated by Notch | REPRESSES | Zap70 | Franco et al PNAS 2006 |