Cell Type Specific Log10 QPCR Expression Values

SynonymCell TypeQPCR ExpressionNormalized ToData From
Notch1CD4-1.26bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1CD4-1.36bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1CD4_24--1.8bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1CD4_69--1.57bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1CD8-1.32bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1CD8-1.31bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1CD8_24--2.02bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1CD8_69--1.57bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DN1-0.6bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN1-0.7bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DN2-0.36bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN2-0.35bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN2-0.54bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DN2a-0.41bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN2a-0.48bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DN3a0.04bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3a-0.08bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3a-0.1bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3a-0.06bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DN3b-0.44bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3b-0.49bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3b-0.66bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DN3b-0.52bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DP-1.41bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DP-0.96bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1DP69--1.58bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1DP69--1bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Notch1GDT-1.39bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Notch1GDT-1.27bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)

Effect of Key Gene Perturbations

SynonymPerturbationQPCR ExpressionRelative ToData From
Notch1BM-1.15ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Notch1Fliver-0.39ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Notch1Mast-0.98ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Notch1Fthymus-0.07ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
Notch1LZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
Notch1LZ_noDL-0.77LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
Notch1LZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Notch1G3_DL-0.26LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Notch1KRRm_DL-0.11LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Notch1LZ_noDL-0.77LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Notch1G3_noDL -1.08LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Notch1KRRm_noDL-0.82LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
Notch1Prmtv_LZ-0.24Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1Prmtv_LZ-0.26Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1Prmtv_PU1-0.65Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1Prmtv_PU1-1.26Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_PU10.06Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_PU1-0.48Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1ProT_PU1-0.08Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_LZ-0.58Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_LZ-0.66Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_LZ-0.41Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_PU1-0.28Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_PU1-0.54Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
Notch1PreT_PU1-0.19Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream NodeInteraction TypeTarget NodeLiterature Evidence
Pax5REPRESSESNotch1Souabni, A. et al.: Busslinger, Immunity. 2002 Dec;17(6):781-93.
DN3 Specific RegulatorPROMOTESNotch1Taghon et al. 2006 Immunity
Notch.CSLPROMOTESNotch1Taghon et al 2007 Nat Immunol
pre-TCR signalREPRESSESNotch1Taghon et al 2006 Immunity
Net E protein activityPROMOTESNotch1Ikawa, T.et al.: Murre J Exp Med. 2006 May 15;203(5):1329-42.
Notch1PROMOTESNotchby definition