| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|---|---|---|
| Gfi1 | REGULATES | Negative inputs | Conjectural link to PU.1 based on cis-regulatory DNA sequence and knockout phenotype |
| TCF-1 | REGULATES | Negative inputs | Rosenbauer, F.et al.: Tenen, Nat Genet. 2006 Jan;38(1):27-37 |
| Ets-repr | PROMOTES | Negative inputs | by definition |
| Ikaros | PROMOTES | Negative inputs | M. Zarnegar unpublished |
| Negative inputs | PROMOTES | Runx + corepressor | Contextual inputs needed to direct Runx effect |