Upstream Node | Interaction Type | Target Node | Literature Evidence |
---|---|---|---|
Gfi1 | REGULATES | Negative inputs | Conjectural link to PU.1 based on cis-regulatory DNA sequence and knockout phenotype |
TCF-1 | REGULATES | Negative inputs | Rosenbauer, F.et al.: Tenen, Nat Genet. 2006 Jan;38(1):27-37 |
Ets-repr | PROMOTES | Negative inputs | by definition |
Ikaros | PROMOTES | Negative inputs | M. Zarnegar unpublished |
Negative inputs | PROMOTES | Runx + corepressor | Contextual inputs needed to direct Runx effect |