Cell Type Specific Log10 QPCR Expression Values

Synonym	Cell Type	QPCR Expression	Normalized To	Data From
Id1	DN1	-3.18	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Id1	DN1	-3.77	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
Id1	DN2	-2.95	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Id1	DN2	-2.76	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
Id1	DN3a	-2.46	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Id1	DN3a	-2.51	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
Id1	DN3b	-3.14	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Id1	DN3b	-3.57	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
Id1	DN4	-2.93	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Id1	DN4	-2.15	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)

Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
Id1	BM	0.21	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Id1	Mast	0.78	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Id1	Fthymus	0.73	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
Id1	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
Id1	LZ_noDL	0.21	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
.
Id1	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
Id1	LZ_noDL	0.01	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
Id1	LZ_DL	0	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Id1	G3_DL	-0.29	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Id1	KRRm_DL	-0.18	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Id1	LZ_noDL	0.01	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Id1	G3_noDL	-0.29	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Id1	KRRm_noDL	-0.15	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
Id1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	DL_PU1	-0.13	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	DL_PU1	0.2	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	DL_PU1	-0.1	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_LZ	0.19	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_LZ	0.29	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_LZ	0.16	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_PU1	0.13	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_PU1	0.2	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Id1	noDL_PU1	0.22	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
GATA-3	REPRESSES	Id1	Taghon, Yui, Rothenberg 2007 Nat. Immunol.
PU.1	REPRESSES	Id1	Franco et al PNAS 2006
Notch.CSL	REPRESSES	Id1	Taghon, Yui, Rothenberg 2007 Nat. Immunol.