| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|
| DN3 Specific Regulator | REPRESSES | High-level GATA-3 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| GATA-3 | PROMOTES | High-level GATA-3 | by definition |
| High-level GATA-3 | PROMOTES | c-Kit | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | PROMOTES | CPA3 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | REPRESSES | Deltex1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | PROMOTES | GATA-1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | PROMOTES | GATA-2 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | PROMOTES | Gfi1B | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | PROMOTES | HES-1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | PROMOTES | Notch-mod. GATA-3 | by definition |
| High-level GATA-3 | REPRESSES | IL-7RAlpha | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Hernandez-Hoyos et al. 2003 Immunity; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | PROMOTES | Mitf | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | REPRESSES | PTAlpha | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | REPRESSES | RAG-1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | PROMOTES | SCL.Tal-1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol.; Anderson, M. K. et al 2002 Devel. Biol. |
| High-level GATA-3 | REPRESSES | LEF-1 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | REPRESSES | Zap70 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | REPRESSES | Id3 | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |
| High-level GATA-3 | PROMOTES | Ikaros | Taghon, Yui, Rothenberg 2007 Nat. Immunol. |