Cell Type Specific Log10 QPCR Expression Values

SynonymCell TypeQPCR ExpressionNormalized ToData From
Gata3CD4-0.72bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3CD4-0.96bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3CD4_24--1.09bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3CD4_69--1.32bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3CD8-1.68bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3CD8-1.44bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3CD8_24--2bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3CD8_69--1.89bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
"GATA3* (different assay, 1 yr later)"DN1-1.28bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
"GATA3* (different assay, 1 yr later)"DN1-1.26bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Gata3DN1-1.11bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN1-1.27bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN1-1.24bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN1-1.31bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
GATA3DN1-1.41bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN1-1.33bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN1-1.82GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN1-2.08GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN1-1.77GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
"GATA3* (different assay, 1 yr later)"DN2-0.86bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
"GATA3* (different assay, 1 yr later)"DN2-0.78bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Gata3DN2-0.62bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN2-0.8bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
GATA3DN2-0.84bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN2-0.99bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN2-1.42GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN2-1.6GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN2-1.72GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Gata3DN2a-0.7bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN2a-0.72bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN2a-0.7bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN2a-0.85bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3DN2b-0.42bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN2b-0.31bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
"GATA3* (different assay, 1 yr later)"DN3a-0.69bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
"GATA3* (different assay, 1 yr later)"DN3a-0.82bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Gata3DN3a-0.62bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.66bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.55bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.47bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.7bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.7bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3a-0.37bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
GATA3DN3a-0.72bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN3a-0.84bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN3a-1.32GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN3a-1.57GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN3a-1.38GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
"GATA3* (different assay, 1 yr later)"DN3b-0.84bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
"GATA3* (different assay, 1 yr later)"DN3b-0.54bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Gata3DN3b-0.7bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3b-0.77bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3b-0.72bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DN3b-0.51bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
GATA3DN3b-0.88bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN3b-0.74bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN3b-1.68GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN3b-1.74GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN3b-1.77GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
"GATA3* (different assay, 1 yr later)"DN4-1.17bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
"GATA3* (different assay, 1 yr later)"DN4-1.01bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN4-0.98bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN4-1.31bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
GATA3DN4-1.72GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN4-2GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3DN4-1.7GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Gata3DP-0.89bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DP-1.04bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3DP69--1.25bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3DP69--1.06bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata3GDT-0.41bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata3GDT-0.35bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
GATA3LSK--2.96GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK--3.42GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK--2.68GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK--2.64GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK--2.33GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK--2.34GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
GATA3LSK+-2.64GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK+-2.33GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK+-2.34GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK+-2.96GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK+-3.42GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3LSK+-2.68GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
GATA3PreM-3.32GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3PreM-3.29GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3PreM-3.51GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3PreM-3.32GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3PreM-3.29GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3PreM-3.51GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
GATA3ProB-3.19GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3ProB-4.21GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3ProB-3.08GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
GATA3ProB-3.19GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3ProB-4.21GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3ProB-3.08GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
GATA3ProT-1.32GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3ProT-1.57GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
GATA3ProT-1.38GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)

Effect of Key Gene Perturbations

SynonymPerturbationQPCR ExpressionRelative ToData From
GATA.3.endogBM-1.85ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogFliver-0.99ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogMast-0.65ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
GATA.3.endogLZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogLZ_noDL-0.15LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
GATA.3.endogLZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogG3_DL-0.02LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogKRRm_DL-0.07LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogLZ_noDL-0.15LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogG3_noDL -0.08LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.3.endogKRRm_noDL-0.15LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
GATA.3LZ_DL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
GATA.3LZ_noDL-0.2LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
.
GATA.3DL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3DL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3DL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3DL_PU10.18DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3DL_PU10.13DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3DL_PU1-0.03DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_LZ-0.08DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_LZ-0.35DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_LZ-0.18DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_PU1-0.7DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_PU1-0.61DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
GATA.3noDL_PU10.06DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
.
GATA.3Prmtv_LZ-0.95Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3Prmtv_LZ-0.51Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3Prmtv_PU1-0.49Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3Prmtv_PU1-0.99Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_PU1-0.47Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_PU1-0.81Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3ProT_PU10.46Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_LZ-0.16Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_LZ-0.44Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_LZ0.78Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_PU1-0.53Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_PU1-0.35Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.3PreT_PU10.52Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
.
GATA3bBM-1.48ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA3bFliver-1.34ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA3bMast-0.66ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
GATA3bLZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
GATA3bLZ_noDL-0.16LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
GATA3bLZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA3bG3_DL1.54LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA3bKRRm_DL1.52LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA3bLZ_noDL-0.16LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA3bG3_noDL 1.52LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA3bKRRm_noDL1.66LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)

Evidence for Interactions

Upstream NodeInteraction TypeTarget NodeLiterature Evidence
c-MybPROMOTESGATA-3Maurice, D.et al.: Weston EMBO J. 2007 Aug 8;26(15):3629-40
Gfi1BREPRESSESGATA-3Xu, W. and Kee, B. L. Blood. 2007 May 15;109(10):4406-14
Net E protein activityPROMOTESGATA-3Gregoire, J.M. & Romeo, P.H. J Biol Chem. 1999 Mar 5;274(10):6567-78; but also see possible downregulation in Xu, W. and Kee, B. L. Blood. 2007 May 15;109(10):4406-14; Ikawa, T.et al.: Murre J Exp Med. 2006 May 15;203(5):1329-42.
Notch.CSLPROMOTESGATA-3Taghon et al. 2005 Genes Dev
GATA-3PROMOTESBcl11BConjectural; based on sequence motifs in conserved noncoding regions
GATA-3REPRESSESPU.1Taghon et al 2007, Nat. Immunol.; Hernandez-Hoyos et al 2003, Immunity; MK Anderson et al. 2002, Developmental Biol.; Scripture-Adams, D. D. & EVR, unpublished; Zarnegar, M. A. & EVR, unpublished
GATA-3PROMOTESTcr-BetaChen F. et al., 2001, J Immunol; Hernandez-Munain & Krangel, 2002, J. Immunol; X. O Yang et al (Willerford). 2003, Blood
GATA-3REPRESSESC.EBPaTaghon, Yui, Rothenberg 2007 Nat. Immunol.
GATA-3REPRESSESId1Taghon, Yui, Rothenberg 2007 Nat. Immunol.
GATA-3REPRESSESIL-7RAlphaTaghon, Yui, Rothenberg 2007 Nat. Immunol.
GATA-3PROMOTESNotch3Taghon, Yui, Rothenberg 2007 Nat. Immunol.; interpreted as physiological because Notch 3 expressed at DN3 stage when GATA-3 is at peak
GATA-3PROMOTESHigh-level GATA-3by definition