Cell Type Specific Log10 QPCR Expression Values

Synonym	Cell Type	QPCR Expression	Normalized To	Data From
Gata2	CD4	-4.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	CD4_24-	-4.23	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	CD4_69-	-5.62	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	CD8	-3.72	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	CD8_24-	-4.27	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	CD8_69-	-5.74	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DN1	-1.47	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN1	-1.08	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DN2	-3.17	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN2	-4.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DN2a	-2.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN2a	-3.07	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DN3a	-3.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN3a	-4.27	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN3a	-4	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DN3b	-4.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN3b	-4.64	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DN3b	-4.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DP	-4.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	DP69-	-4.82	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	DP69-	-5.21	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Gata2	GDT	-4.46	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Gata2	GDT	-4.57	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)

Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
GATA.2	BM	1.19	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA.2	Fliver	1.49	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA.2	Mast	3.72	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
GATA.2	Fthymus	0.82	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
GATA.2	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
GATA.2	LZ_noDL	0.15	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
GATA.2	LZ_DL	0	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.2	G3_DL	0.75	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.2	KRRm_DL	0.81	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.2	LZ_noDL	0.15	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.2	G3_noDL	1.09	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
GATA.2	KRRm_noDL	1.36	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
GATA.2	Prmtv_LZ	1.18	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	Prmtv_LZ	-2.57	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	Prmtv_PU1	-0.63	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	Prmtv_PU1	-3.12	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_PU1	-1.22	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_PU1	-2.67	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	ProT_PU1	-0.33	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_LZ	-0.63	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_LZ	-3.07	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_LZ	0.24	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_PU1	-0.82	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_PU1	-3	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
GATA.2	PreT_PU1	-0.16	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
GATA-2	PROMOTES	GATA-2	Grass, J.A., et al.: Bresnick, Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8811-6
DN2, DN3 Stage Negative Regulator	REPRESSES	GATA-2	Tydell et al. 2007 J. Immunol.
High-level GATA-3	PROMOTES	GATA-2	Taghon, Yui, Rothenberg 2007 Nat. Immunol.
GATA-2	PROMOTES	c-Kit	Taghon, Yui, Rothenberg 2007 Nat. Immunol.
GATA-2	PROMOTES	CPA3	Taghon, Yui, Rothenberg 2007 Nat. Immunol.