| Synonym | Perturbation | QPCR Expression | Relative To | Data From |
|---|
| Egr2 | LZ_DL | 0 | LZ,DL | Notch-Delta interaction data (Franco et al. 2006 PNAS) |
| Egr2 | LZ_noDL | -0.04 | LZ,DL | Notch-Delta interaction data (Franco et al. 2006 PNAS) |
| . | | | | |
| Egr2 | DL_LZ | 0 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | DL_LZ | 0 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | DL_LZ | 0 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | DL_PU1 | 0.2 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | DL_PU1 | 0.52 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | DL_PU1 | 0.56 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_LZ | -0.25 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_LZ | 0.14 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_LZ | -0.02 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_PU1 | 0.16 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_PU1 | 0.33 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Egr2 | noDL_PU1 | 0.5 | DL,LZ | PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS) |
| Upstream Node | Interaction Type | Target Node | Literature Evidence |
|---|
| Gfi1 | REPRESSES | Egr2 | Laslo, P.et al.: Singh Cell. 2006 Aug 25;126(4):755-66 |
| pre-TCR signal | PROMOTES | Egr2 | Carleton, M.et al.: Wiest J Immunol. 2002 Feb 15;168(4):1649-58.; Taghon et al 2006 Immunity (note that most expression is in gamma delta T cells) |
| PU1 activity | PROMOTES | Egr2 | Laslo, P.et al.: Singh Cell. 2006 Aug 25;126(4):755-66; and Franco et al 2006 PNAS, and Dionne et al. 2005 Devel. Biol. |
| Egr2 | REPRESSES | Gfi1 | Laslo, P.et al.: Singh Cell. 2006 Aug 25;126(4):755-66 |
| Egr2 | PROMOTES | M-CSF-R | Krysinska,H,et al.: Bonifer Mol Cell Biol. 2007 Feb;27(3):878-87 |
| Egr2 | PROMOTES | Egr2+3 | by definition |