Cell Type Specific Log10 QPCR Expression Values

Synonym	Cell Type	QPCR Expression	Normalized To	Data From
Dtx1	CD4	-1.89	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	CD4	-1.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	CD4_24-	-1.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	CD4_69-	-1.8	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	CD8	-1.57	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	CD8	-1.33	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	CD8_24-	-2.14	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	CD8_69-	-1.46	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	DN1	-2.27	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN1	-2.36	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN1	-3.19	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN1	-4.17	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN1	-4	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Dtx1	DN1	-2.16	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN1	-2.72	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN1	-2.08	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN1	-3.12	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	DN2	-2.26	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN2	-2.24	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN2	-4.3	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN2	-4.3	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN2	-3.15	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Dtx1	DN2	-3.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2	-2.36	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2	-2.21	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	DN2a	-2.06	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2a	-2	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2a	-2	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2a	-1.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	DN2b	-2.6	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN2b	-2.46	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	DN3a	-0.77	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN3a	-0.77	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN3a	-2.34	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN3a	-2.43	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN3a	-2.17	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Dtx1	DN3a	-0.82	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3a	-1.12	bActin	Intrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3a	-0.7	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3a	-1.26	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3a	-0.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3a	-0.82	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	DN3b	-1.2	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN3b	-1.62	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN3b	-2.26	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN3b	-2.64	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN3b	-2.68	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Dtx1	DN3b	-1.66	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3b	-1.68	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3b	-1.92	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DN3b	-1.62	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	DN4	-1.66	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN4	-2.87	bActin	Immature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
Deltex1	DN4	-3.21	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN4	-2.43	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	DN4	-2.46	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Dtx1	DP	-3.01	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DP	-2.64	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	DP69-	-2.38	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	DP69-	-2.39	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Dtx1	GDT	-1.96	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Dtx1	GDT	-2	bActin	Intrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Deltex1	LSK-	-5.22	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK-	-4.52	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK-	-5.7	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK-	-5.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK-	-6	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK-	-4.96	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Deltex1	LSK+	-5.52	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK+	-5.7	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK+	-6	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK+	-4.92	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK+	-4.7	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	LSK+	-5.22	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Deltex1	PreM	-3.92	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	PreM	-4.62	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	PreM	-5.4	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	PreM	-4.54	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	PreM	-5.19	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	PreM	-5.68	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Deltex1	ProB	-4	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProB	-4.8	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProB	-5.15	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProB	-4.34	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProB	-5.52	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProB	-5.4	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Deltex1	ProT	-1.27	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProT	-1.02	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProT	-1.09	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProT	-1.27	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProT	-1.02	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Deltex1	ProT	-1.09	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)

Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
Deltex.1	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
Deltex.1	LZ_noDL	-2.38	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
.
Deltex.1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	DL_PU1	-0.11	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	DL_PU1	-0.38	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	DL_PU1	-0.16	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_LZ	-2.25	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_LZ	-2.66	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_LZ	-2.22	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_PU1	-2.93	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_PU1	-2.35	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Deltex.1	noDL_PU1	-2.3	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
.
Deltex1	BM	-1.93	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Deltex1	Mast	-3.51	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
Deltex1	Fthymus	0.05	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
Deltex1	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
Deltex1	LZ_noDL	-2.37	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
Deltex1	LZ_DL	0	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Deltex1	G3_DL	-0.39	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Deltex1	KRRm_DL	-0.29	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Deltex1	LZ_noDL	-2.37	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Deltex1	G3_noDL	-2.99	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Deltex1	KRRm_noDL	-2.85	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
Deltex1	Prmtv_LZ	-0.27	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	Prmtv_LZ	-0.51	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	Prmtv_PU1	-0.12	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	Prmtv_PU1	-0.74	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_LZ	0	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_PU1	0.22	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_PU1	-0.36	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	ProT_PU1	0.09	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_LZ	0.6	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_LZ	-0.03	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_LZ	0.17	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_PU1	0.21	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_PU1	0.04	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)
Deltex1	PreT_PU1	0.67	Pro-T,LZ	PU.1 Effects per stage data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
Notch.CSL	PROMOTES	Deltex1	Taghon et al 2005 Genes Dev; Franco et al. 2006 PNAS; Taghon et al 2007 Nat Immunol; many earlier references
pre-TCR signal	REPRESSES	Deltex1	Taghon et al 2006 Immunity
High-level GATA-3	REPRESSES	Deltex1	Taghon, Yui, Rothenberg 2007 Nat. Immunol.