Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
CPA3	BM	-0.46	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
CPA3	Fliver	0.57	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
CPA3	Mast	2.2	Thymus	GATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
CPA3	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
CPA3	LZ_noDL	0.08	LZ,DL	Notch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
CPA3	LZ_DL	0	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CPA3	G3_DL	0.59	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CPA3	KRRm_DL	0.5	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CPA3	LZ_noDL	0.08	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CPA3	G3_noDL	1.12	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CPA3	KRRm_noDL	1.06	LZ,DL	Over Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
GATA-2	PROMOTES	CPA3	Taghon, Yui, Rothenberg 2007 Nat. Immunol.
High-level GATA-3	PROMOTES	CPA3	Taghon, Yui, Rothenberg 2007 Nat. Immunol.