Cell Type Specific Log10 QPCR Expression Values

SynonymCell TypeQPCR ExpressionNormalized ToData From
CD3gCD4-2.19bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gCD4-0.43bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gCD4_24--0.89bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gCD4_69--0.82bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gCD8-0.19bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gCD8-0.66bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gCD8_24--0.96bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gCD8_69--0.85bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDN1-3.1bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN1-4.31bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDN20.32bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN20.04bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN2-0.48bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDN2a-1.47bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN2a-1.02bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDN3a0.48bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3a0.26bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3a0.34bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3a0.65bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDN3b0.04bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3b0.04bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3b-0.11bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDN3b0.08bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDP-0.21bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDP-0.06bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gDP69--0.96bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gDP69--0.09bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3gGDT-0.42bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3gGDT-0.42bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)

Effect of Key Gene Perturbations

SynonymPerturbationQPCR ExpressionRelative ToData From
CD3gLZ_DL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
CD3gLZ_noDL-0.03LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
.
CD3gLZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
CD3gLZ_noDL-0.23LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
CD3gLZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3gG3_DL0.02LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3gKRRm_DL0.09LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3gLZ_noDL-0.23LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3gG3_noDL -0.24LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3gKRRm_noDL-0.12LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
CD3gDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gDL_PU1-0.2DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gDL_PU1-0.21DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gDL_PU1-0.29DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_LZ-0.01DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_LZ-0.04DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_LZ-0.05DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_PU1-0.32DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_PU1-0.47DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3gnoDL_PU1-0.37DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream NodeInteraction TypeTarget NodeLiterature Evidence
Specification initiatorPROMOTESCD3gRothenberg, Moore, Yui 2008 Nat Rev Immunol
PU.1 modulated by Notch.DLREPRESSESCD3gFranco et al PNAS 2006
Notch.CSLPROMOTESCD3gTaghon, Yui, Rothenberg 2007 Nat. Immunol.
CD3gPROMOTESCD3by definition