Cell Type Specific Log10 QPCR Expression Values

SynonymCell TypeQPCR ExpressionNormalized ToData From
CD3eCD4-0.25bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eCD4-0.57bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eCD4_24--0.28bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eCD4_69--0.37bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eCD8-0.34bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eCD8-0.35bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eCD8_24--0.57bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eCD8_69--0.47bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN1-3.98bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN1-4.25bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN1-3.44bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN1-3.27bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN1-3.74bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN1-3.62bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN2-2.2bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN2-2.17bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN2-0.29bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2-0.55bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2-1bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN2a-2.07bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2a-1.92bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2a-1.82bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2a-1.92bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN2b-0.49bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN2b-0.54bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN3a-0.62bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN3a-0.59bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN3a-0.03bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3a-0.2bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3a0.2bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3a0.15bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3a0.08bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3a0.3bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN3b-1.11bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN3b-1.15bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN3b-0.17bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3b-0.25bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3b-0.38bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDN3b-0.12bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDN4-1.41bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
CD3eDN4-1.4bActinImmature Thymocyte Gene Expression Data (David-Fung et al. 2006 Immunological Reviews)
.
CD3eDP-0.14bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDP-0.38bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eDP69--0.49bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eDP69--0.31bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
CD3eGDT-0.51bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
CD3eGDT-0.52bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)

Effect of Key Gene Perturbations

SynonymPerturbationQPCR ExpressionRelative ToData From
CD3eBM-1.96ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
CD3eFliver-4.1ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
CD3eMast-2.66ThymusGATA-3 Expression, Other Tissues (Taghon et al. 2007 Nat. Immunol)
.
CD3eLZ_DL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
CD3eLZ_noDL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
.
CD3eLZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
CD3eLZ_noDL-0.35LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
CD3eLZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3eG3_DL-0.14LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3eKRRm_DL0.03LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3eLZ_noDL-0.35LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3eG3_noDL -0.38LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
CD3eKRRm_noDL-0.24LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
CD3eDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3eDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3eDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3eDL_PU1-0.24DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3eDL_PU1-0.18DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3eDL_PU1-0.14DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_LZ-0.09DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_LZ0.02DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_LZ0.06DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_PU1-0.65DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_PU1-0.45DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
CD3enoDL_PU1-0.39DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
.
CD3ePrmtv_LZ-0.87Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePrmtv_LZ-0.47Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePrmtv_PU1-0.84Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePrmtv_PU1-1.09Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_LZ0Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_PU1-0.38Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_PU1-0.38Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3eProT_PU1-0.55Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_LZ-0.15Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_LZ-0.25Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_LZ-0.31Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_PU1-0.19Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_PU1-0.36Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)
CD3ePreT_PU1-0.57Pro-T,LZPU.1 Effects per stage data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream NodeInteraction TypeTarget NodeLiterature Evidence
CD3EpsilonPROMOTESCD3by definition; major complex component
CD3gPROMOTESCD3by definition
Specification initiatorPROMOTESCD3EpsilonRothenberg, Moore, Yui 2008 Nat Rev Immunol
PU.1 modulated by Notch.DLREPRESSESCD3EpsilonFranco et al PNAS 2006
Notch.CSLPROMOTESCD3EpsilonTaghon, Yui, Rothenberg 2007 Nat. Immunol.
CD3PROMOTESPre-TCRIntegral component of pre-TCR