Cell Type Specific Log10 QPCR Expression Values

SynonymCell TypeQPCR ExpressionNormalized ToData From
Bcl11bCD4-1.47bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bCD4-1.68bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bCD4_24--1.8bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bCD4_69--1.42bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bCD8-1.89bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bCD8-2.03bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bCD8_24--2.18bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bCD8_69--1.72bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bDN1-3.85bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN1-4.41bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN1-4.15bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN1-4.31bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN1-4.52GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN1-3.96GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN1-1.85GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bDN2-1.37bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2-1.44bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2-1.51bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2-1.54GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN2-1.68GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN2-1.54GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bDN2a-1.82bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2a-1.8bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2a-1.8bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2a-1.74bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bDN2b-1.15bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN2b-1.24bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bDN3a-0.96bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-1.33bActinIntrathymic T Cell Precursors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-0.77bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-1.17bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-1.12bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-1bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3a-1.37GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN3a-1.48GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN3a-1.47GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bDN3b-1.34bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3b-1.64bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3b-1.52bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3b-1.42bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDN3b-1.8GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN3b-1.96GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN3b-1.8GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bDN4-1.82GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN4-1.85GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bDN4-1.85GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bDP-1.22bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDP-1.37bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bDP69--1.41bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bDP69--1.33bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bGDT-1.57bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
Bcl11bGDT-1.85bActinIntrathymic T Cell Precursors vs. Myeloid Progenitors (Rothenberg, Moore, and Yui 2008, Nat. Rev. Immunology)
.
Bcl11bLSK--5.22GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK--4.52GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK--5.7GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK--3.92GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK--4.29GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK--4.74GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bLSK+-3.82GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK+-4.21GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK+-4.37GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK+-5.3GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK+-4.7GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bLSK+-5.3GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bPreM-4.96GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bPreM-6.15GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bPreM-5.7GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bPreM-5.7GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bPreM-6.05GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bPreM-5.64GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bProB-5.7GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProB-6.1GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProB-5.15GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProB-6.15GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProB-6.05GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProB-5GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11bProT-1.37GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProT-0.89GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProT-0.82GAPDLSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProT-1.8GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProT-1.4GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11bProT-1.42GAPDLSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)

Effect of Key Gene Perturbations

SynonymPerturbationQPCR ExpressionRelative ToData From
Bcl11BLZ_DL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
Bcl11BLZ_noDL0LZ,DLNotch-Delta interaction data (Franco et al. 2006 PNAS)
.
Bcl11bLZ_DL0LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
Bcl11bLZ_noDL-0.26LZ,DLNotch-Delta interaction data (Taghon et al. 2007 Nat. Immunol)
.
Bcl11bLZ_DL0LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Bcl11bG3_DL-0.06LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Bcl11bKRRm_DL0.01LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Bcl11bLZ_noDL-0.26LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Bcl11bG3_noDL -0.38LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
Bcl11bKRRm_noDL-0.16LZ,DLOver Expressed GATA-3 (Taghon et al. 2007 Nat. Immunol)
.
Bcl11BDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BDL_LZ0DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BDL_PU1-0.12DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BDL_PU1-0.26DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BDL_PU1-0.56DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_LZ0.01DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_LZ-0.2DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_LZ0.18DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_PU1-0.97DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_PU1-0.71DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11BnoDL_PU1-0.69DL,LZPU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream NodeInteraction TypeTarget NodeLiterature Evidence
GATA-3PROMOTESBcl11BConjectural; based on sequence motifs in conserved noncoding regions
TCF-1PROMOTESBcl11BConjectural, based on cis-regulatory sequence and expression pattern
PU.1 modulated by Notch.DLREPRESSESBcl11BFranco et al PNAS 2006
Specification initiatorPROMOTESBcl11BC.C. Tydell et al 2007 J Immunol.
Bcl11BPROMOTESDN2, DN3 Stage Negative RegulatorConjectural: from expression pattern and known repressor function