Cell Type Specific Log10 QPCR Expression Values

Synonym	Cell Type	QPCR Expression	Normalized To	Data From
Bcl11a	DN1	-1.46	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN1	-1.35	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN1	-1.96	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	DN2	-2.12	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN2	-2	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN2	-2.66	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	DN3a	-2.64	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN3a	-2.44	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN3a	-2.54	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	DN3b	-2.72	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN3b	-3.01	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN3b	-3.08	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	DN4	-3.62	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN4	-3.55	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	DN4	-3.52	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	LSK-	-1.43	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK-	-1.34	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK-	-1.35	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK-	-1.49	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK-	-1.43	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK-	-1.51	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	LSK+	-1.49	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK+	-1.43	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK+	-1.51	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK+	-1.43	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK+	-1.34	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	LSK+	-1.35	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	PreM	-1.96	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	PreM	-2.21	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	PreM	-2.54	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	PreM	-1.96	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	PreM	-2.21	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	PreM	-2.54	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	ProB	-1.21	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProB	-1.35	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProB	-1.38	GAPD	LSK vs DN Stages (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProB	-1.21	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProB	-1.35	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProB	-1.38	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
.
Bcl11a	ProT	-2.64	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProT	-2.44	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)
Bcl11a	ProT	-2.54	GAPD	LSK vs ProT, ProB and pre-myeloid expressions (Tydell et al. 2007, The Journal of Immunology)

Effect of Key Gene Perturbations

Synonym	Perturbation	QPCR Expression	Relative To	Data From
Bcl11A	LZ_DL	0	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
Bcl11A	LZ_noDL	-0.09	LZ,DL	Notch-Delta interaction data (Franco et al. 2006 PNAS)
.
Bcl11A	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	DL_LZ	0	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	DL_PU1	0.83	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	DL_PU1	0.07	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	DL_PU1	0.98	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_LZ	0.01	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_LZ	-0.36	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_LZ	0.06	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_PU1	0.77	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_PU1	0.13	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)
Bcl11A	noDL_PU1	0.8	DL,LZ	PU.1-Notch signaling interaction data (Franco et al. 2006 PNAS)

Evidence for Interactions

Upstream Node	Interaction Type	Target Node	Literature Evidence
PU1 activity	PROMOTES	Bcl11A	Franco et al 2006 PNAS