R. Andrew Cameron

Director, Center for Computational Regulatory Genomics,
Beckman Institute

Senior Research Associate in Biology

Research Interests:

 
Genomic Approaches to the Study of Developmental Biology
 and Reproductive Biology of Marine Invertebrates
Larval Ecology and Settlement
Population Genetics.

Selected Publications

Cameron, R. A., G. Mahairas, J. P. Rast, P. Martinez, T. R. Biondi, S. Schwartzell, J. C. Wallace, A. Poustka, B. T. Livingston, G. A. Wray, C. A. Ettensohn, H. Lehrach, R. J. Britten, E. H. Davidson. (2000). A sea urchin genome project: Sequence scan, virtual map, and additional resources. PNAS 97, 9514-9518.

Davidson, E. H., Rast, J. P., Oliveri, P., Ransick, A., Calestani, C., Yuh, C.-H., Minokawa, T., Amore, G., Hinman, V., Arenas-Mena, C., Otim, O., Brown, C. T., Livi, C. B., Lee, P., Revilla, R., Rust, A. G., Pan, Z. J., Schilstra, M. J. Clarke, P. J. C., Arnone, M. I., Rowen, L., Cameron, R. A., McClay, D. R., Hood, L. and Bolouri, H. (2002). A genomic regulatory network for development. Science 295, 1669-1678.

Rast, J. P., Cameron, R. A., Poustka, A. J. and Davidson, E. H. (2002). brachyury target genes in the early sea urchin embryo isolated by differential macroarray screening. Dev. Biol. 246, 191-208.

Brown, C. T., Rust, A. G., Clarke, P. J. C., Pan, Z., Schilstra, M. J., De Buysscher, T., Griffin, G., Wold, B. J., Cameron, R. A., Davidson, E. H. and Bolouri, H. (2002). New computational approaches for analysis of cis-regulatory networks. Dev. Biol. 246, 86-102.

Britten, R. J., Rowen, L., Williams, J., and Cameron, R. A. Majority of divergence between closely related DNA samples is due to indels. Proc. Natl. Acad. Sci. USA 100, 4661-4665, 2003.

Hinman, V. F., Nguyen, A., Cameron, R. A. and Davidson, E. H. Developmental gene regulatory network architecture across 500 MYA of echinoderm evolution.. Proc. Natl. Acad. Sci. USA 100, 13356-13361.

Poustka, A. J., Groth, D., Hennig, S., Thamm, S., Cameron, A., Beck, A., Reinhardt, R., Herwig, R., Panopoulou, G. and Lehrach, H. (2003) Generation, annotation, evolutionary analysis and database integration of 20,000 unique sea urchin EST clusters. Genome Res 13: 2736-2746.

R. A. Cameron, P. Oliveri, J. Wyllie, and E. H. Davidson (2004) cis-Regulatory Activity of Randomly Chosen Genomic Fragments from the Sea Urchin. Gene Expression Patterns 4, 205-213.

Brown, C. T. Xie, Y., Davidson, E. H. and Cameron, R. A. paircomp, FamilyRelationsII and Cartwheel: tools for interspecific sequence comparison. BMC BioInformatics 6, Art. No. 70, March 24, 2005

Cameron, R. A., Chow, S. H., Berney, K., Chiu, T-Y., Yuan, Q-A., Krämer, A., Helguero, A., Ransick, A., Yun, M., and Davidson, E. H. (2005) An evolutionary constraint: strongly disfavored class of change in DNA sequence during divergence of cis-regulatory modules. Proc. Natl. Acad. Sci. USA 102: 11769-11774.

Cameron R. A., Rowen L., Nesbitt, R., Bloom S., Rast, J. P., Berney, K., Arenas-Mena, C, Martinez, P., Lucas, S., Richardson, P. M., Davidson E. H., Peterson K, J., and Hood, L. (2006) Unusual Gene Order and Organization of the Sea Urchin Hox Cluster. J. Exp. Zool. (Mol. Dev. Evol.) 304B:1–14.

Bottjer, D. J., Davidson, E. H., Peterson, K. J., Cameron, R. A. 2006. Paleogenomics of echinoderms. Science 314: 956- 960.

The Sea Urchin Sequencing Consortium. 2006. The Purple Sea Urchin Genome. Science, 314: 941-952.

Samanta, Manoj P., Tongprasit, Waraporn, Istrail, Sorin, Cameron, R. Andrew, Tu, Qiang, Davidson, Eric H., Stolc, Viktor. 2006. The transcriptome of the sea urchin embryo. Science 314: 960- 962.

Arenas-Mena, C., Cameron, R. A., Davidson, Eric H. 2006. Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo. Dev. Growth & Differ. 48: 463-472

Howard-Ashby, M., Brown, C. T., Materna, S. C, Chen, L, Davidson, E. H. Gene families encoding transcription factors expressed in early development of Strongylocentrotus purpuratus. Developmental Biology, 300: 90-107.

Materna; S. C., Berney, K., Cameron. R. A. 2006. The Strongylocentrotus purpuratus genome: A comparative perspective. Developmental Biology, 300: 485-495.

LINKS

Sea Urchin Genome Project web site.

The NCBI Sea Urchin Web Page

The Baylor HGSC Sea Urchin Page

The Sea Urchin Gene Catalog (RZPD)

The Macro-array filter manual

The simple sequence repeat sequences

How to find me:

1. Room 224 in the Beckman Institute on the Caltech Campus
2. VOICE (626)395-8421
3. FAX (626)793-3047
4. e-mail: acameron@caltech.edu

Last updated 4-24-2005